Zobrazeno 1 - 10
of 2 151
pro vyhledávání: '"HSCs, Hematopoietic stem cells"'
Autor:
Samiksha Wasnik, Jeffrey Xiao, Chien-Shing Chen, Do Hyun Kim, Mark E. Reeves, David J. Baylink, Ashley Howard, Olivia L. Francis, Hector Moz, Saied Mirshahidi, Huynh Cao, Yi Xu, Guido Marcucci
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1252-1260 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1252-1260 (2021)
T cell based immunotherapies can be applicable to acute myeloid leukemia (AML). Therefore, the selection of optimal T cells, cell manufacturing, and therapeutic T cell engineering are essential for the development of effective adoptive T cell therapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8631938224952c24db64ba170babb9e6
http://europepmc.org/articles/PMC8603025
http://europepmc.org/articles/PMC8603025
Autor:
Ortega-Gomez, Almudena, Lopez, Sergio, Varela, Lourdes M, Jaramillo, Sara, Muriana, Francisco J G, Abia, Rocio
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
13 Páginas.-- 6 Figuras
Chronic administration of a high-fat diet in mice has been established to influence the generation and trafficking of immune cells such as neutrophils in the bone marrow, the dysregulation of which may contribute to a wi
Chronic administration of a high-fat diet in mice has been established to influence the generation and trafficking of immune cells such as neutrophils in the bone marrow, the dysregulation of which may contribute to a wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f2d1d1a6b88167aeb9d5bc960f647f
https://api.elsevier.com/content/abstract/scopus_id/85137303972
https://api.elsevier.com/content/abstract/scopus_id/85137303972
Autor:
Kenneth Mautner, Peter A. Everts, Natalie Stephens, Joshua B. Rothenberg, Gerard A. Malanga, Rowan V. Paul
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 11, Iss, Pp 56-64 (2019)
Regenerative Therapy, Vol 11, Iss, Pp 56-64 (2019)
Autologous biologics, defined as platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMC), are cell-based therapy treatment options in regenerative medicine practices, and have been increasingly used in orthopedics, sports medicine, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518f452f1e9602ff98132126dfba606c
http://europepmc.org/articles/PMC6517793
http://europepmc.org/articles/PMC6517793
Publikováno v:
Translational Oncology, Vol 14, Iss 4, Pp 101022-(2021)
Translational Oncology
Translational Oncology
Highlights • Chemotherapy, radiotherapy and autoimmune disorder can cause thrombocytopenia in cancer patients. • The implications of platelet transfusion on cancer progression; a “vicious circle”. • Mechanisms and signaling pathways of tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ebd83f60a7a114b2e18b3ee306a081
http://www.sciencedirect.com/science/article/pii/S1936523321000140
http://www.sciencedirect.com/science/article/pii/S1936523321000140
Autor:
Douglas R. Almeida-Silveira, Guilherme A. dos Santos, Carolina Hassibe Thomé, Gustavo A. de Souza, Germano Aguiar Ferreira, Vitor M. Faça, Jan Jacob Schuringa, Eduardo Magalhães Rego, Diego A Pereira-Martins, Isabel Weinhäuser, Roos Houtsma
Publikováno v:
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics, 20:100091. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Molecular & Cellular Proteomics, 20:100091. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Non–T cell activation linker (NTAL) membrane protein depletion from lipid rafts by alkylphospholipids or downregulation by shRNA knockdown decreases cell viability through regulation of the Akt/PI3K pathway in mantle cell lymphoma and acute promyel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91d0d2b79fafc839615c82675824133
https://pubmed.ncbi.nlm.nih.gov/33971369
https://pubmed.ncbi.nlm.nih.gov/33971369
Autor:
Ferri Soheilian, Velayoudame Parthibane, Lino Tessarollo, Kunio Nagashima, Stephen D. Fox, Jonathan R. Keller, Usha Acharya, Diwash Acharya, Jairaj K. Acharya, Thiruvaimozhi Abimannan, Thorkell Andresson, Jing Lin, Sargur Madabushi Srideshikan, Acong Yang, Kimberly D. Klarmann
Publikováno v:
The Journal of Biological Chemistry
Serine palmitoyltransferase complex (SPT) mediates the first and rate-limiting step in the de novo sphingolipid biosynthetic pathway. The larger subunits SPTLC1 and SPTLC2/SPTLC3 together form the catalytic core while a smaller third subunit either S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606cdc99de1fa4a63be60d50f2854748
https://pubmed.ncbi.nlm.nih.gov/33662400
https://pubmed.ncbi.nlm.nih.gov/33662400
Autor:
Shervin Shokouhi, Atieh Pourbagheri-Sigaroodi, Mahda Delshad, Behzad Poopak, Davood Bashash, Ava Safaroghli-Azar
Publikováno v:
International Immunopharmacology
Graphical abstract
Despite endorsed and exponential research to improve diagnostic and therapeutic strategies, efforts have not yet converted into a better prospect for patients infected with the novel coronavirus (2019nCoV), and still, the name
Despite endorsed and exponential research to improve diagnostic and therapeutic strategies, efforts have not yet converted into a better prospect for patients infected with the novel coronavirus (2019nCoV), and still, the name
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2be46e6fa902f44f432915663dea1db
https://doi.org/10.1016/j.intimp.2021.107995
https://doi.org/10.1016/j.intimp.2021.107995
Publikováno v:
Journal of Bone Oncology, Vol 30, Iss, Pp 100387-(2021)
Journal of Bone Oncology
Journal of Bone Oncology
Highlights • Bone is densely innervated by sensory nerves. • Excitation of the sensory nerve nociceptor TRPV1 induces cancer-associated bone pain and promotes cancer progression in bone. • Sensory nerve TRPV1 is a therapeutic target for cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a66aab1d51bf11872fd626857d563d0
https://doi.org/10.1016/j.jbo.2021.100387
https://doi.org/10.1016/j.jbo.2021.100387
Publikováno v:
EBioMedicine, Vol 69, Iss, Pp 103427-(2021)
EBioMedicine
EBioMedicine
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial inflammation and progressive joint destruction and is a primary cause of disability worldwide. Despite the existence of numerous anti-rheumatic drugs, a sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e59ac03e508af98279e7efcb573e18b9
https://doi.org/10.1016/j.ebiom.2021.103427
https://doi.org/10.1016/j.ebiom.2021.103427
Autor:
Yunbing Shen, Anatoly Dubnovitsky, Zsolt Kasza, Maria Bettini, Sanjay V. Boddul, William W. Kwok, Vivianne Malmström, Bruno Raposo, Aaron Winkler, Lars Klareskog, Ravi Sharma, Vaishnavi Srinivasan Iyer, Fredrik Wermeling, Christina Gerstner
Publikováno v:
Journal of Translational Autoimmunity
Journal of Translational Autoimmunity, Vol 4, Iss, Pp 100087-(2021)
Journal of Translational Autoimmunity, Vol 4, Iss, Pp 100087-(2021)
Recent advances in single-cell sequencing technologies enable the generation of large-scale data sets of paired TCR sequences from patients with autoimmune disease. Methods to validate and characterize patient-derived TCR data are needed, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4ec6f35bd5ce462fdebe9813a58868
https://doi.org/10.1016/j.jtauto.2021.100087
https://doi.org/10.1016/j.jtauto.2021.100087