Zobrazeno 1 - 10
of 12
pro vyhledávání: '"HSC70, heat shock cognate 70"'
Autor:
Arun Upadhyay
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2995-3014 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Cells have different sets of molecules for performing an array of physiological functions. Nucleic acids have stored and carried the information throughout evolution, whereas proteins have been attributed to performing most of the cellular functions.
Autor:
Annika Höhn, Daniela Weber, Tobias Jung, Christiane Ott, Martin Hugo, Bastian Kochlik, Richard Kehm, Jeannette König, Tilman Grune, José Pedro Castro
Publikováno v:
Redox Biology, 11: 482-501
Redox Biology
Redox Biology, Vol 11, Iss, Pp 482-501 (2017)
Redox Biology
Redox Biology, Vol 11, Iss, Pp 482-501 (2017)
Aging is a complex phenomenon and its impact is becoming more relevant due to the rising life expectancy and because aging itself is the basis for the development of age-related diseases such as cancer, neurodegenerative diseases and type 2 diabetes.
Autor:
Jianhua Zhang, Matthew Redmann, Victor M. Darley-Usmar, Laura A. Volpicelli-Daley, Willayat Yousuf Wani
Publikováno v:
Redox Biology
Redox Biology, Vol 11, Iss, Pp 429-437 (2017)
Redox Biology, Vol 11, Iss, Pp 429-437 (2017)
Parkinson's disease is a debilitating neurodegenerative disorder that is pathologically characterized by intracellular inclusions comprised primarily of alpha-synuclein (αSyn) that can also be transmitted from neuron to neuron. Several lines of evid
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 4, Iss C, Pp 683-688 (2014)
FEBS Open Bio, Vol 4, Iss C, Pp 683-688 (2014)
Highlights • To elucidate vRNP export, we investigated the interactions among Hsc70, M1, and NS2. • Hsc70 interacts with M1 more strongly than with NS2. • Hsc70 competes with NS2 for M1 binding. • These results suggest the involvement of Hsc7
Publikováno v:
ASN NEURO
ASN Neuro, Vol 4 (2012)
ASN Neuro, Vol 4 (2012)
Modulating molecular chaperones is emerging as an attractive approach to treat neurodegenerative diseases associated with protein aggregation, DPN (diabetic peripheral neuropathy) and possibly, demyelinating neuropathies. KU-32 [ N-(7-((2 R,3 R,4 S,5
Autor:
Nigel A. Calcutt
Publikováno v:
ASN NEURO
ASN neuro, vol 2, iss 4
ASN Neuro, Vol 2 (2010)
ASN neuro, vol 2, iss 4
ASN Neuro, Vol 2 (2010)
Increasing the expression of Hsp70 (heat-shock protein 70) can inhibit sensory neuron degeneration after axotomy. Since the onset of DPN (diabetic peripheral neuropathy) is associated with the gradual decline of sensory neuron function, we evaluated
Akademický článek
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Akademický článek
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Autor:
Upadhyay A; Department of Biochemistry, Central University of Rajasthan, Bandar Sindari, Kishangarh, Ajmer, Rajasthan 305817, India.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Oct; Vol. 11 (10), pp. 2995-3014. Date of Electronic Publication: 2021 Jan 07.
Autor:
Watanabe K; Laboratory of Molecular Biology of Infectious Agents, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan., Shimizu T; Laboratory of Molecular Biology of Infectious Agents, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan., Noda S; Laboratory of Molecular Biology of Infectious Agents, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan., Tsukahara F; Department of Pharmacology, Tokyo Women's Medical University, School of Medicine, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan., Maru Y; Department of Pharmacology, Tokyo Women's Medical University, School of Medicine, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan., Kobayashi N; Laboratory of Molecular Biology of Infectious Agents, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan ; Central Research Center, AVSS Corporation, 1-22, Wakaba-machi, Nagasaki 852-8137, Japan.
Publikováno v:
FEBS open bio [FEBS Open Bio] 2014 Jul 09; Vol. 4, pp. 683-8. Date of Electronic Publication: 2014 Jul 09 (Print Publication: 2014).