Zobrazeno 1 - 5
of 5
pro vyhledávání: '"HRMS, high resolution mass spectra"'
Autor:
Yi-Chao Zheng, Yue-Jiao Liu, Li-Ying Ma, Yinghua You, Haojie Wang, Hong-Min Liu, Yang Feifei, Chao-Ya Ma
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 9, Pp 1658-1668 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Histone lysine specific demethylase 1 (LSD1) has become a potential therapeutic target for the treatment of cancer. Discovery and develop novel and potent LSD1 inhibitors is a challenge, although several of them have already entered into clinical tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8ed8f9fce726a289b0ae8847cad43d
https://doi.org/10.1016/j.apsb.2020.02.006
https://doi.org/10.1016/j.apsb.2020.02.006
Autor:
Axel Knebel, Lorna Plater, Christoph H. Emmerich, Sam Strickson, Natalia Shpiro, Philip Cohen, David G. Campbell, Maria Stella Ritorto
Publikováno v:
Biochemical Journal
The compound BAY 11-7082 inhibits IκBα [inhibitor of NF-κB (nuclear factor κB)α] phosphorylation in cells and has been used to implicate the canonical IKKs (IκB kinases) and NF-κB in >350 publications. In the present study we report that BAY 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af6008194e741619655a2e05fd75147
https://doi.org/10.1042/bj20121651
https://doi.org/10.1042/bj20121651
Autor:
Lawrence H. Pinto, Santiago Vázquez, Lieve Naesens, María D. Duque, Mathy Froeyen, Chunlong Ma, Eva Torres, Pelayo Camps, Evelien Vanderlinden
Publikováno v:
Antiviral Research
Highlights • We report on the synthesis of polycyclic amines designed as ring-rearranged analogs of amantadine. • Only one compound inhibited A/M2 proton channel function. • However, they showed low-micromolar activity against A/H1N1, but not A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a47734c2752df8a5d424ccb9b16e8c
https://pubmed.ncbi.nlm.nih.gov/23800838
https://pubmed.ncbi.nlm.nih.gov/23800838
Autor:
Wu D; School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Zheng X; School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China., Liu R; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Li Z; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Jiang Z; School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China., Zhou Q; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Huang Y; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Wu XN; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Zhang C; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Huang YY; School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Luo HB; School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2022 Mar; Vol. 12 (3), pp. 1351-1362. Date of Electronic Publication: 2021 Sep 30.
Autor:
Ma L; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Wang H; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., You Y; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Ma C; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Liu Y; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Yang F; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Zheng Y; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Liu H; Collaborative Innovation Center of New Drug Research and Safety Evaluation, Henan Province; Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China; Key Laboratory of Henan Province for Drug Quality and Evaluation; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Sep; Vol. 10 (9), pp. 1658-1668. Date of Electronic Publication: 2020 Feb 24.