Zobrazeno 1 - 10
of 288
pro vyhledávání: '"HPV16 E6"'
Publikováno v:
陆军军医大学学报, Vol 46, Iss 7, Pp 715-724 (2024)
Objective To explore the effects of HPV16 E6 on genes and signaling pathways in cervical epithelial cells and to screen genes associated with oncogenic transformation. Methods HUCEC models infected with HPV16 E6 were constructed, and transcriptome se
Externí odkaz:
https://doaj.org/article/91778ef6433344788e683ce5a283860c
Publikováno v:
Cancer Medicine, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Background Cervical cancer (CC) has become the fourth most common cancer worldwide and it is mainly caused by the infection of human papillomavirus (HPV), especially high‐risk HPV16. Aberrant miRNA expression in CC is closely related to HP
Externí odkaz:
https://doaj.org/article/68a538460018461092460188c4fd6d2c
Autor:
Huizhen Xin, Zhenzhen Pan, Xiangyi Zhe, Chunhe Zhang, Hongtao Li, Weinan Zheng, Haichen Long, Renfu Shao, Dongmei Li, Zemin Pan
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background To investigate the genotype distribution of human papillomavirus (HPV) in infected Uygur and Han women in Xinjiang, China; analyze the HPV16 E6 gene polymorphism site and relationship with the development of cervical cancer. Metho
Externí odkaz:
https://doaj.org/article/192fc68b7602474b8646f5a5f52a5b88
Autor:
Shujuan Shu, Zhi Li, Liu Liu, Xia Ying, Yina Zhang, Ting Wang, Xiaoye Zhou, Peiyue Jiang, Weiguo Lv
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Human papillomaviruses (HPV), mainly HPV16 and HPV18, of high-risk classification are involved in cervical cancer carcinogenesis and progression. Octamer-binding transcription factor 4 (OCT4) is a key transcription factor that is increased in various
Externí odkaz:
https://doaj.org/article/11df421498574c5b829f13b9740cb2bc
Autor:
Francesca Paolini, Carla Amici, Mariantonia Carosi, Claudia Bonomo, Paola Di Bonito, Aldo Venuti, Luisa Accardi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-11 (2021)
Abstract Background The oncogenic activity of the high risk human papillomavirus type 16 (HPV16) is fully dependent on the E6 and E7 viral oncoproteins produced during viral infection. The oncoproteins interfere with cellular homeostasis by promoting
Externí odkaz:
https://doaj.org/article/0df7aadddb4048348870b9c52b122571
Autor:
Li Song, Rui Mao, Ling Ding, Zhiqiang Tian, Mingxuan Zhang, Jiahao Wang, Ming Wang, Yuanjing Lyu, Chunliang Liu, Meijuan Feng, Haixia Jia, Jintao Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
hnRNP E1 (heterogeneous nuclear ribonucleoprotein E1) is an important RNA-binding protein (RBPs) that plays a vital role in tumor development. Human papillomavirus 16 (HPV16) contains numerous sites that can bind to RNA/DNA and may be modified by mul
Externí odkaz:
https://doaj.org/article/4be39729c589417f91fefd2f8529d1e8
Autor:
Yunuen Ortiz-Pedraza, J. Omar Muñoz-Bello, Lucio Antonio Ramos-Chávez, Imelda Martínez-Ramírez, Leslie Olmedo-Nieva, Joaquín Manzo-Merino, Alejandro López-Saavedra, Verónica Pérez-de la Cruz, Marcela Lizano
Publikováno v:
Viruses, Vol 15, Iss 2, p 324 (2023)
Persistent high-risk human papillomavirus infection is the main risk factor for cervical cancer establishment, where the viral oncogenes E6 and E7 promote a cancerous phenotype. Metabolic reprogramming in cancer involves alterations in glutamine meta
Externí odkaz:
https://doaj.org/article/5e0ef9cfe4f1408a8aba44285c94372d
Autor:
Ye-Fei Chang, Guo-Ji Yan, Guang-Cai Liu, Ying Hong, Hong-Lan Chen, Shui Jiang, Yong Zhong, Yan-Bin Xiyang, Tao Hu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Cervical cancer, which is significantly associated with high-risk human papillomavirus (HPV) infection, currently ranks the fourth most common cancer among women worldwide. Previous literature reported that the elevated expression of G6PD was signifi
Externí odkaz:
https://doaj.org/article/b2155945d77f40739f23749fa7a7d4f9
Autor:
A. M. Heeren, J. Rotman, A. G. M. Stam, N. Pocorni, A. A. Gassama, S. Samuels, M. C. G. Bleeker, C. H. Mom, H. J. M. A. A. Zijlmans, G. G. Kenter, E. S. Jordanova, T. D. de Gruijl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Cervical cancer (CxCa) is mainly a locally invading disease that metastasizes to loco-regional lymph node basins before involving distant organs in more advanced stages. Local immune potentiation of tumor-draining lymph nodes (TDL
Externí odkaz:
https://doaj.org/article/fd94363d85aa4764bcae05c3da897418
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