Zobrazeno 1 - 10
of 273
pro vyhledávání: '"HPV integration"'
Autor:
Anurag Kumar Singh, Kaivalya Walavalkar, Daniele Tavernari, Giovanni Ciriello, Dimple Notani, Radhakrishnan Sabarinathan
Publikováno v:
Molecular Oncology, Vol 18, Iss 5, Pp 1189-1208 (2024)
Human papillomavirus (HPV) infections are the primary drivers of cervical cancers, and often HPV DNA gets integrated into the host genome. Although the oncogenic impact of HPV encoded genes is relatively well known, the cis‐regulatory effect of int
Externí odkaz:
https://doaj.org/article/01261b876af14c5ab98346a530512cef
Autor:
Sara Bønløkke, Torben Steiniche, Boe Sandahl Sorensen, Gitte‐Bettina Nyvang, Jacob Christian Lindegaard, Jan Blaakær, Jesper Bertelsen, Katrine Fuglsang, Mikael Lenz Strube, Suzan Lenz, Magnus Stougaard
Publikováno v:
Molecular Oncology, Vol 18, Iss 5, Pp 1231-1244 (2024)
For cervical cancer (CC), circulating cell‐free HPV DNA (ccfHPV) may establish disease severity. Furthermore, HPV integration has been correlated to viral load and survival. In this study, pre‐treatment plasma from 139 CC cases (50 primary surger
Externí odkaz:
https://doaj.org/article/ff0349f899b14681a67f3aa4b23c11ad
Autor:
Zhijie Wang, Chen Liu, Wanxin Liu, Xinyi Lv, Ting Hu, Fan Yang, Wenhui Yang, Liang He, Xiaoyuan Huang
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Cervical cancer (CC) causes more than 311,000 deaths annually worldwide. The integration of human papillomavirus (HPV) is a crucial genetic event that contributes to cervical carcinogenesis. Despite HPV DNA integration is known to
Externí odkaz:
https://doaj.org/article/912c30bda58e4decbfe7699305d6f954
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundThe integration of human papillomavirus (HPV) is closely related to the occurrence of cervical cancer. However, little is known about the complete state of HPV integration into the host genome.MethodsIn this study, three HPV-positive cell l
Externí odkaz:
https://doaj.org/article/e60019efe78f463187ca99c5a74dab2f
Autor:
Marc-Andre Gauthier, Adway Kadam, Gary Leveque, Nahid Golabi, Anthony Zeitouni, Keith Richardson, Marco Mascarella, Nader Sadeghi, Sampath Kumar Loganathan
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionIn North America and in most European countries, Human Papillomavirus (HPV) is responsible for over 70% of oropharyngeal squamous cell carcinomas. The burden of OPSCC, in high-income countries, has been steadily increasing over the past 2
Externí odkaz:
https://doaj.org/article/98bf1d1e716244e18c8631cd9691833b
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Autor:
Juliette Mainguené, Sophie Vacher, Maud Kamal, Abderaouf Hamza, Julien Masliah‐Planchon, Sylvain Baulande, Sabrina Ibadioune, Edith Borcoman, Wulfran Cacheux, Valentin Calugaru, Laura Courtois, Carole Crozes, Marc Deloger, Elodie Girard, Jean‐Pierre Delord, Antoine Dubray‐Vautrin, Linda Larbi Chérif, Celia Dupain, Emmanuelle Jeannot, Jerzy Klijanienko, Sonia Lameiras, Charlotte Lecerf, Anouchka Modesto, Alain Nicolas, Roman Rouzier, Esma Saada‐Bouzid, Pierre Saintigny, Anne Sudaka, Nicolas Servant, Christophe Le Tourneau, Ivan Bièche
Publikováno v:
Molecular Oncology, Vol 16, Iss 16, Pp 3001-3016 (2022)
A prevalence of around 26% of human papillomavirus (HPV) in head and neck squamous cell carcinoma (HNSCC) has been previously reported. HPV induced oncogenesis mainly involving E6 and E7 viral oncoproteins. In some cases, HPV viral DNA has been detec
Externí odkaz:
https://doaj.org/article/d06dd36b1af84cd3acb67648ff2cbc2c
Autor:
Junpeng Fan, Yu Fu, Wenju Peng, Xiong Li, Yuanming Shen, Ensong Guo, Funian Lu, Shengtao Zhou, Si Liu, Bin Yang, Xu Qin, Dianxing Hu, Rourou Xiao, Xi Li, Siqi Yang, Cunzhong Yuan, Yao Shu, He Huang, Ting Wan, Yanan Pi, Shuxiang Wang, Wenjuan Chen, Haixia Wang, Lin Zhong, Li Yuan, Baogang Wen, Beihua Kong, Gordon B. Mills, Dongling Zou, Bairong Xia, Kun Song, Gang Chen, Ding Ma, Chaoyang Sun
Publikováno v:
Cell Genomics, Vol 3, Iss 1, Pp 100211- (2023)
Summary: Cervical cancer (CC) that is caused by high-risk human papillomavirus (HPV) remains a significant public health problem worldwide. HPV integration sites can be silent or actively transcribed, leading to the production of viral-host fusion tr
Externí odkaz:
https://doaj.org/article/bff3c82c7b0c42a981e3527afcfa2e4e
Akademický článek
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