Zobrazeno 1 - 10
of 61
pro vyhledávání: '"HPTN 071"'
Autor:
Abenathi Mcinziba, Peter Bock, Graeme Hoddinott, Janet Seeley, Virginia Bond, Sarah Fidler, Lario Viljoen
Publikováno v:
AIDS Research and Therapy, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract Background South Africa is reported to have the highest burden of HIV with an estimated 8.2 million people living with HIV (PLHIV) in 2021- despite adopting the World Health Organisation (WHO) universal HIV test and treat (UTT) recommendatio
Externí odkaz:
https://doaj.org/article/5a069c0aaa15418dbc9fd24124529675
Autor:
Wendy Grant‐McAuley, Estelle Piwowar‐Manning, William Clarke, Autumn Breaud, Kidist Belay Zewdie, Ayana Moore, Helen Mary Ayles, Barry Kosloff, Kwame Shanaube, Peter Bock, Sue‐Ann Meehan, Gerald Maarman, Sarah Fidler, Richard Hayes, Deborah Donnell, Susan H. Eshleman, for the HPTN 071 (PopART) Study Team
Publikováno v:
Journal of the International AIDS Society, Vol 26, Iss 10, Pp n/a-n/a (2023)
Abstract Introduction HIV controllers have low viral loads (VL) without antiretroviral treatment (ART). We evaluated viraemic control in a community‐randomized trial conducted in Zambia and South Africa that evaluated the impact of a combination pr
Externí odkaz:
https://doaj.org/article/b2c0c8c3efe346ffbdaed8b6335fa7d5
Autor:
William J M Probert, Rafael Sauter, Michael Pickles, Anne Cori, Nomtha F Bell-Mandla, Justin Bwalya, Lucie Abeler-Dörner, Peter Bock, Deborah J Donnell, Sian Floyd, David Macleod, Estelle Piwowar-Manning, Timothy Skalland, Kwame Shanaube, Ethan Wilson, Blia Yang, Helen Ayles, Sarah Fidler, Richard J Hayes, Christophe Fraser, Richard Hayes, Nulda Beyers, Wafaa El-Sadr, Myron Cohen, Susan Eshleman, Yaw Agyei, Virginia Bond, Graeme Hoddinott, Deborah Donnell, Lynda Emel, Heather Noble, David Burns, Nirupama Sista, Sam Griffith, Ayana Moore, Tanette Headen, Rhonda White, Eric Miller, James Hargreaves, Katharina Hauck, Ranjeeta Thomas, Mohammed Limbada, Kalpana Sabapathy, Ab Schaap, Rory Dunbar, Musonda Simwinga, Peter Smith, Sten Vermund, Nomtha Mandla, Nozizwe Makola, Anneen van Deventer, Anelet James, Karen Jennings, James Kruger, Mwelwa Phiri, Barry Kosloff, Lawrence Mwenge, Sarah Kanema, William Probert, Ramya Kumar, Ephraim Sakala, Andrew Silumesi, Tim Skalland, Krista Yuhas
Publikováno v:
e780
e771
e771
Background The long-term impact of universal home-based testing and treatment as part of universal testing and treatment (UTT) on HIV incidence is unknown. We made projections using a detailed individual-based model of the effect of the intervention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c5fe31b9ffd9ed588c38c3ec97821b
https://doi.org/10.1016/s2352-3018(22)00259-4
https://doi.org/10.1016/s2352-3018(22)00259-4
Akademický článek
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Akademický článek
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Autor:
Abigail Harper, Lawrence Mwenge, Katharina Hauck, Blia Yang, Ranjeeta Thomas, Michael Pickles, Rafael Sauter, Helen Ayles, Sian Floyd, Surya Singh, Ronelle Burger, William J. M. Probert, Sarah Kanema, Sarah Fidler, Nosivuyile Vanqa, Anne Cori, Kwame Shanaube, Mwelwa Phiri, Christophe Fraser, Richard J. Hayes, Deborah Donnell, Justin Bwalya, Peter Bock, Nomtha Bell-Mandla
Publikováno v:
The Lancet. Global Health
e680
e668
e680
e668
Summary Background The HPTN 071 (PopART) trial showed that a combination HIV prevention package including universal HIV testing and treatment (UTT) reduced population-level incidence of HIV compared with standard care. However, evidence is scarce on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67225b313aedda7bb4618ea119eff301
https://doi.org/10.1016/s2214-109x(21)00034-6
https://doi.org/10.1016/s2214-109x(21)00034-6
Autor:
Mohammed Limbada, Ab Schaap, Helen Ayles, Chiti Bwalya, David Macleod, Sarah Fidler, Richard J. Hayes, Sian Floyd, Vasty Situmbeko
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-12 (2021)
Trials
Trials
Background Following the World Health Organization’s (WHO) 2015 guidelines recommending initiation of antiretroviral therapy (ART) irrespective of CD4 count for all people living with HIV (PLHIV), many countries in sub-Saharan Africa have adopted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c279ef6a8326c77d3f7023916a9ab6dd
https://doaj.org/article/1d6a088ead534dcbaa7acdfdc41cd819
https://doaj.org/article/1d6a088ead534dcbaa7acdfdc41cd819
Autor:
Mohammed Limbada, David Macleod, Vasty Situmbeko, Ellen Muhau, Osborn Shibwela, Bwalya Chiti, Sian Floyd, Albertus J Schaap, Richard Hayes, Sarah Fidler, Helen Ayles, Nulda Beyers, Peter Bock, Wafaa El-Sadr, Myron Cohen, Virginia Bond, Susan Eshleman, Deborah Donnell, Graeme Hoddinott, Dave Macleod, David Burns, Christopher Fraser, Lynda Emel, Heather Noble, Anne Cori, Niru Sista, Sam Griffith, Ayana Moore, Tanette Headen, Rhonda White, Eric Miller, James Hargreaves, Katharina Hauck, Ranjeeta Thomas, Justin Bwalya, Alwyn Mwinga, Michael Pickles, Kalpana Sabapathy, Mwelwa Phiri, Lawrence Mwenge, Rory Dunbar, Kwame Shanaube, Blia Yang, Musonda Simwinga, Peter C Smith, Nomtha Mandla, Nozizwe Makola, Anneen Van Deventer, Ephraim Sakala, Karen Jennings, Barry Kosloff, Sarah Kanema, Will Probert, Ramya Kumar, Andrew Silumesi, Tim Skalland, Krista Yuhas
Publikováno v:
E23
E13
The Lancet. HIV
E13
The Lancet. HIV
Summary Background Non-facility-based antiretroviral therapy (ART) delivery for people with stable HIV might increase sustainable ART coverage in low-income and middle-income countries. Within the HPTN 071 (PopART) trial, two interventions, home-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7f5d1290f4f9fbf7bfe964842021fa
http://hdl.handle.net/10044/1/98139
http://hdl.handle.net/10044/1/98139
Autor:
Tanya Golubchik, Ab Schaap, Helen Ayles, Susan H. Eshleman, Eleanor Barnes, Barry Kosloff, David Bonsall, Lucie Abeler-Dörner, Ethan Wilson, Anthony Brown, Chris Wymant, Estelle Piwowar-Manning, Mariateresa de Cesare, Sarah Fidler, Christophe Fraser, Rory Bowden, G MacIntyre-Cockett, Matthew Hall, Lynda Emel, M. Azim Ansari, Richard J. Hayes, Hptn (PopART) Study Team, Mohammed Limbada
Viral genetic sequencing can be used to monitor the spread of HIV drug resistance, identify appropriate antiretroviral regimes, and characterize transmission dynamics. Despite decreasing costs, next-generation sequencing (NGS) is still prohibitively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892b86b366b6ba36aa8200491e0b959e
https://ora.ox.ac.uk/objects/uuid:b62da195-cc19-4b57-ad0e-76e539018005
https://ora.ox.ac.uk/objects/uuid:b62da195-cc19-4b57-ad0e-76e539018005
Autor:
Peter Bock, Estelle Piwowar-Manning, Richard J. Hayes, Sarah Fidler, Robert Hinch, Anne Cori, Rafael Sauter, Hptn (PopART) Study Team, Sian Floyd, Michael Pickles, Deborah Donnell, Christophe Fraser, Ethan Wilson, Helen Ayles, William J. M. Probert
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009301 (2021)
PLoS Computational Biology
PLoS Computational Biology
Mathematical models are powerful tools in HIV epidemiology, producing quantitative projections of key indicators such as HIV incidence and prevalence. In order to improve the accuracy of predictions, such models need to incorporate a number of behavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546bc695bb33a6a505d56dd6677fd345
https://doaj.org/article/affef60ff94443cda079aebd0c49e70c
https://doaj.org/article/affef60ff94443cda079aebd0c49e70c