Sexually transmitted infections among HIV serodiscordant partners: A secondary analysis of HIV Prevention Trial Network 052

Autor: Myron S. Cohen, Victor Akelo, Emily Shava, José Henrique Pilotto, Mulinda Nyirenda, Ravindre Panchia, Maganizo Chagomerana, Suwat Chariyalertsak, Mina C. Hosseinipour, Sheela Godbole, Sharlaa Badal-Faesen

Publikováno v: International Journal of STD & AIDS. 32:1204-1211

Sexually transmitted infections (STIs) remain a public health concern because of their interaction(s) with HIV. In the HPTN 052 study, STIs were evaluated in both HIV-positive index cases and their HIV-negative partners at enrollment and at yearly fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c4557632fe438f44db321b9773aed3
https://doi.org/10.1177/09564624211030368

How to Evolve the Response to the Global HIV Epidemic With New Metrics and Targets Based on Pre-Treatment CD4 Counts

Autor: McKaylee Robertson, Denis Nash

Publikováno v: Current HIV/AIDS Reports. 16:304-313

Early diagnosis and treatment of HIV following seroconversion improves individual and population health. Using published data on pre-treatment CD4 cell counts, we benchmarked the level of immunodeficiency at HIV diagnosis and ART initiation in the �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea6772492e07c40571b469cf8089ce3
https://doi.org/10.1007/s11904-019-00452-7

Brief Report: Impact of Early Antiretroviral Therapy on the Performance of HIV Rapid Tests and HIV Incidence Assays

Autor: Dean Soko, Tamara Walsky, Gerald Tegha, Mina C. Hosseinipour, Ying Q. Chen, Laeyendecker Oliver, Theresa Gamble, Ethan A. Wilson, Katherine Schlusser, Barbara Debevec, Estelle Piwowar-Manning, Johnstone Kumwenda, Marybeth McCauley, Susan H. Eshleman, Myron S. Cohen, Jessica M. Fogel

Publikováno v: JAIDS Journal of Acquired Immune Deficiency Syndromes. 75:426-430

BACKGROUND Antiretroviral therapy (ART) can downregulate antibody responses to HIV infection. We evaluated the impact of early vs. delayed ART on the performance of HIV diagnostic and incidence assays. METHODS Samples were obtained from 207 participa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20f54e103304913b6bddda431cc5c8a4
https://doi.org/10.1097/qai.0000000000001421

How have guidelines on when to start antiretroviral therapy affected survival of people living with HIV infection?

Autor: Alison Rodger, Caroline A. Sabin

Publikováno v: Current Opinion in HIV and AIDS. 11:487-491

Purpose of review Until recently, conflicting data led to discrepancies in guideline recommendation on 'when to start' antiretroviral therapy (ART) in asymptomatic HIV infection. This review focuses on evidence underpinning guidelines over the past d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37391efa3a1c5a501a6e99685c7eb1a
https://doi.org/10.1097/coh.0000000000000307

Brief Report: Per Sex-Act Risk of HIV Transmission Under Antiretroviral Treatment: A Data-Driven Approach

Autor: Virginie Supervie, Romulus Breban

Publikováno v: Journal of Acquired Immune Deficiency Syndromes-JAIDS
Journal of Acquired Immune Deficiency Syndromes-JAIDS, 2018, 79 (4), pp.440--444. ⟨10.1097/QAI.0000000000001845⟩

International audience; Background: Before the completion of HPTN 052, PARTNER, and Opposites Attract studies, data were lacking to directly estimate HIV transmission risk under effective combined antiretroviral treatment (cART). Rather, estimates we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c7a8565a3d91ff745fc693834118a4
https://pubmed.ncbi.nlm.nih.gov/30179982