Zobrazeno 1 - 10
of 205
pro vyhledávání: '"HOWARD OCHMAN"'
Publikováno v:
PLoS Biology, Vol 22, Iss 5, p e3002418 (2024)
The phenomenon of de novo gene birth-the emergence of genes from non-genic sequences-has received considerable attention due to the widespread occurrence of genes that are unique to particular species or genomes. Most instances of de novo gene birth
Externí odkaz:
https://doaj.org/article/e05767fb22544b2b81098c99445323b5
Publikováno v:
mSystems, Vol 8, Iss 4 (2023)
ABSTRACT The genus Salmonella comprises two species, Salmonella bongori and Salmonella enterica, which are infectious to a wide variety of animal hosts. The diversity within S. enterica has been further partitioned into 6–10 subspecies based on suc
Externí odkaz:
https://doaj.org/article/dfac9e9114534342bf883487a497e31c
Autor:
Alex H. Nishida, Howard Ochman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Here the authors sequence 16S rRNA and the more variable gyrase B protein-coding gene to profile the gut microbiome of captive great apes, which together with analysis of wild apes and humans, reveal a displacement of bacterial strains normally restr
Externí odkaz:
https://doaj.org/article/e9d549bd4ee4484ab554976b0b0959c9
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Microviruses encompass an astonishing array of small, single-stranded DNA phages that, due to the surge in metagenomic surveys, are now known to be prevalent in most environments. Current taxonomy concedes the considerable diversity within t
Externí odkaz:
https://doaj.org/article/8de1aac521c849d6b97f1772b0630755
Autor:
Louis-Marie Bobay, Howard Ochman
Publikováno v:
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Knowledge of population-level processes is essential to understanding the efficacy of selection operating within a species. However, attempts at estimating effective population sizes (Ne) are particularly challenging in bacteria d
Externí odkaz:
https://doaj.org/article/d048c06c45794e1aa6639ad5dcb63e59
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009272 (2020)
The Betacoronaviruses comprise multiple subgenera whose members have been implicated in human disease. As with SARS, MERS and now SARS-CoV-2, the origin and emergence of new variants are often attributed to events of recombination that alter host tro
Externí odkaz:
https://doaj.org/article/f62055af790a46a28b7ff5ff10b0e0a6
Autor:
Paul C Kirchberger, Howard Ochman
Publikováno v:
eLife, Vol 9 (2020)
Gokushoviruses are single-stranded, circular DNA bacteriophages found in metagenomic datasets from diverse ecosystems worldwide, including human gut microbiomes. Despite their ubiquity and abundance, little is known about their biology or host range:
Externí odkaz:
https://doaj.org/article/b7f2e1041a13404daf2c7d0fd10ae88d
Autor:
Charles C. Traverse, Howard Ochman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 7, Pp 2257-2264 (2018)
Although mutations are the basis for adaptation and heritable genetic change, transient errors occur during transcription at rates that are orders of magnitude higher than the mutation rate. High rates of transcription errors can be detrimental by ca
Externí odkaz:
https://doaj.org/article/95e312a8ed644bd988e8870ba1952dab
Publikováno v:
PeerJ, Vol 6, p e4286 (2018)
The maintenance of a G + C content that is higher than the mutational input to a genome provides support for the view that selection serves to increase G + C contents in bacteria. Recent experimental evidence from Escherichia coli demonstrated that s
Externí odkaz:
https://doaj.org/article/b081f547f0e84dc9810ffc68b27deb39
Autor:
Charles C. Traverse, Howard Ochman
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Advances in sequencing technologies have enabled direct quantification of genome-wide errors that occur during RNA transcription. These errors occur at rates that are orders of magnitude higher than rates during DNA replication, but due to t
Externí odkaz:
https://doaj.org/article/0d9ffbb3c48b48899459215fc3e96771