Zobrazeno 1 - 10
of 83
pro vyhledávání: '"HOOK1"'
Autor:
Elisa Suárez-Martínez, Sander R. Piersma, Thang V. Pham, Irene V. Bijnsdorp, Connie R. Jimenez, Amancio Carnero
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Ovarian cancer has a high mortality rate mainly due to its resistance to currently used therapies. This resistance has been associated with the presence of cancer stem cells (CSCs), interactions with the microenvironment, and intr
Externí odkaz:
https://doaj.org/article/af08a23f399f4704a81219517ab21154
Akademický článek
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Autor:
Lei Yin, Wenjia Li, Xuxiao Chen, Ronghao Wang, Tao Zhang, Jialin Meng, Zhao Li, Li Xu, Rui Yin, Bo Cheng, Huan Yang
Publikováno v:
Advanced Science, Vol 10, Iss 17, Pp n/a-n/a (2023)
Abstract Accumulating evidence shows HOOK1 disordered in human malignancies. However, the clinicopathological and biological significance of HOOK1 in renal cell carcinoma (RCC) remains rarely studied. In this study, the authors demonstrate that HOOK1
Externí odkaz:
https://doaj.org/article/dc1a1e76464d4fbf837435e975ae41e0
Akademický článek
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Akademický článek
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Autor:
Monika Dzieciatkowska, V. Adani, J. B. Troung, A. Aguilar-Maldonado, S. L. Reck-Peterson, A. A. Kendrick, Jenna R. Christensen
In eukaryotic cells, intracellular components are organized by the microtubule motors cytoplasmic dynein-1 (dynein) and kinesins, which are linked to cargos via adaptor proteins. While ∼40 kinesins transport cargo toward the plus end of microtubule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b3249b6738138f03f158786e4f41284
https://doi.org/10.1101/2021.10.07.463551
https://doi.org/10.1101/2021.10.07.463551
Publikováno v:
Molecular Biology of the Cell
The heterotetrameric adaptor protein complex 4 (AP-4) is a component of a protein coat associated with the trans-Golgi network (TGN). Mutations in AP-4 subunits cause a complicated form of autosomal-recessive hereditary spastic paraplegia termed AP-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a82710d5ec844ce6ea5dd05d74c29c
http://europepmc.org/articles/PMC7185972
http://europepmc.org/articles/PMC7185972
Publikováno v:
OncoTargets and Therapy, Vol Volume 12, Pp 5897-5906 (2019)
Lingjuan He,1 Yinyan Li,1 Xin Huang,1 Hongqiang Cheng,2 Yuehai Ke,2 Linrun Wang11Department of Pharmacy, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang, People’s Republic of China; 2Department of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::c2865ce62706c1cd1d1fe405a820d334
https://www.dovepress.com/the-prognostic-significance-of-shp2-and-its-binding-protein-hook1-in-n-peer-reviewed-article-OTT
https://www.dovepress.com/the-prognostic-significance-of-shp2-and-its-binding-protein-hook1-in-n-peer-reviewed-article-OTT
Publikováno v:
OncoTargets and Therapy. 12:5897-5906
Background We previously reported that Hook1 inhibits the phosphatase activity of SHP2 in the regulation of the epithelial-mesenchymal transition (EMT) in lung cancer. In this study, we performed a comprehensive analysis of SHP2 and Hook1 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::480656a8d586d982f8ecb6fdfa78377c
https://doi.org/10.2147/ott.s210223
https://doi.org/10.2147/ott.s210223
Autor:
In-Gyun Lee, Clara Franzini-Armstrong, Malgorzata Boczkowska, Mara A. Olenick, Erika L.F. Holzbaur, Roberto Dominguez
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Cytoplasmic dynein is the major minus-end-directed microtubule-based motor in cells. Dynein processivity and cargo selectivity depend on cargo-specific effectors that, while generally unrelated, share the ability to interact with dynein and dynactin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ad36f9b94e27a90ec592434a65fbac
https://doaj.org/article/1906ae3d8b11421f880a7d0604e616ad
https://doaj.org/article/1906ae3d8b11421f880a7d0604e616ad