Zobrazeno 1 - 10
of 26
pro vyhledávání: '"HONG-QIANG YU"'
Autor:
Xun Li, Cheng-Cheng Zhang, Xiao-Tong Lin, Jie Zhang, Yu-Jun Zhang, Hong-Qiang Yu, Ze-Yu Liu, Yi Gong, Lei-Da Zhang, Chuan-Ming Xie
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 1, Pp 177-191 (2024)
Abstract Dysregulation of wild-type p53 turnover is a key cause of hepatocellular carcinoma (HCC), yet its mechanism remains poorly understood. Here, we report that WD repeat and SOCS box containing protein 2 (WSB2), an E3 ubiquitin ligase, is an ind
Externí odkaz:
https://doaj.org/article/2c7fc086db7d42de8764d2dbdedb0c80
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-21 (2023)
Abstract Background Kirsten rat sarcoma (KRAS) and mutant KRASG12D have been implicated in human cancers, but it remains unclear whether their activation requires ubiquitination. This study aimed to investigate whether and how F-box and leucine-rich
Externí odkaz:
https://doaj.org/article/d151a4fc625b4a2e88890dd81e3f9729
Autor:
Jie Zhang, Xiao-Tong Lin, Hong-Qiang Yu, Lei Fang, Di Wu, Yuan-Deng Luo, Yu-Jun Zhang, Chuan-Ming Xie
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 10, Pp 2281-2286 (2023)
Externí odkaz:
https://doaj.org/article/d2459e6d198d4d6e825f12c6a08b3f39
Autor:
Jie Zhang, Xiao-Tong Lin, Hong-Qiang Yu, Lei Fang, Di Wu, Yuan-Deng Luo, Yu-Jun Zhang, Chuan-Ming Xie
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 10, Pp 2162-2176 (2023)
Abstract Metastatic hepatocellular carcinoma (HCC) is the most lethal malignancy and lacks effective treatment. FBXL6 is overexpressed in human hepatocellular carcinoma (HCC), but whether this change drives liver tumorigenesis and lung metastasis in
Externí odkaz:
https://doaj.org/article/41ed2f7d1856484f91e86601fcf0dbbc
Autor:
Xiao-Tong Lin, Jie Zhang, Ze-Yu Liu, Di Wu, Lei Fang, Chun-Ming Li, Hong-Qiang Yu, Chuan-Ming Xie
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112812- (2023)
Summary: Hepatocellular carcinoma (HCC), the most common liver cancer, occurs mainly in men, but the underlying mechanism remains to be further explored. Here, we report that ubiquitinated glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is responsib
Externí odkaz:
https://doaj.org/article/0992248c1e2047dd80432990e087a50f
Autor:
Yuan‐Deng Luo, Hong‐Qiang Yu, Xiao‐Yu Liu, Deng Huang, Hai‐Su Dai, Lei Fang, Yu‐Jun Zhang, Jie‐Juan Lai, Yan Jiang, Ling Shuai, Lei‐Da Zhang, Geng Chen, Ping Bie, Chuan‐Ming Xie
Publikováno v:
Cancer Medicine, Vol 9, Iss 12, Pp 4083-4094 (2020)
Abstract Purpose Hepatocellular carcinoma (HCC) is a common malignant cancer and the third leading cause of death worldwide. The molecular mechanism of HCC remains unclear. Recent studies have demonstrated that the ubiquitin‐proteasome system (UPS)
Externí odkaz:
https://doaj.org/article/3acd50238a3f44eaba329814ac32cc5f
Autor:
Di Wu, Hong-Qiang Yu, Hao-Jun Xiong, Yu-Jun Zhang, Xiao-Tong Lin, Jie Zhang, Wu Wu, Teng Wang, Xiao-Yu Liu, Chuan-Ming Xie
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The sodium pump α3 subunit is associated with colorectal liver metastasis. However, the underlying mechanism involved in this effect is not yet known. In this study, we found that the expression levels of the sodium pump α3 subunit were positively
Externí odkaz:
https://doaj.org/article/7776092030c84bd58743d561dfa6b0f1
Autor:
Xiao-Tong Lin, Hong-Qiang Yu, Lei Fang, Ye Tan, Ze-Yu Liu, Di Wu, Jie Zhang, Hao-Jun Xiong, Chuan-Ming Xie
Publikováno v:
eLife, Vol 10 (2021)
Dysregulation of tumor-relevant proteins may contribute to human hepatocellular carcinoma (HCC) tumorigenesis. FBXO45 is an E3 ubiquitin ligase that is frequently elevated expression in human HCC. However, it remains unknown whether FBXO45 is associa
Externí odkaz:
https://doaj.org/article/5535088d5ea945d986f77c586a332b66
Autor:
Ye Tan, Di Wu, Ze-Yu Liu, Hong-Qiang Yu, Xiang-Ru Zheng, Xiao-Tong Lin, Ping Bie, Lei- Da Zhang, Chuan-Ming Xie
Publikováno v:
Journal of Molecular Cell Biology.
Helicase-like transcription factor (HLTF) has been found to be involved in the maintenance of genome stability and tumour suppression, but whether its downregulation in cancers is associated with posttranslational regulation remains unclear. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8cff0ce6972985668afc41ce585f090
https://doi.org/10.1093/jmcb/mjad012
https://doi.org/10.1093/jmcb/mjad012
