Zobrazeno 1 - 10
of 126
pro vyhledávání: '"HNRNPL"'
Publikováno v:
Translational Oncology, Vol 43, Iss , Pp 101908- (2024)
Objective: This study probed into the effect of HNRNPL on ferroptosis in hepatocellular carcinoma (HCC) cells and related molecular mechanisms. Methods: Expression patterns of HNRNPL, Recombinant S100 Calcium Binding Protein A9 (S100A9) were analyzed
Externí odkaz:
https://doaj.org/article/bc0f298212fc483ab94b5aadbfb80aba
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e22281- (2023)
Background: CFTR nonsense alleles generate negligible CFTR protein due to the nonsense mutation: 1) triggering CFTR mRNA degradation by nonsense-mediated mRNA decay (NMD), and 2) terminating CFTR mRNA translation prematurely. Thus, people with cystic
Externí odkaz:
https://doaj.org/article/9e629d4a91ce4cbf9f1e3d5c01d0b1f2
Autor:
Zhongzhong Jiang, Yugang Jiang
Publikováno v:
Neurobiology of Disease, Vol 181, Iss , Pp 106080- (2023)
Background: Ischemic stroke (IS) is the primary cause of mortality and disability worldwide. Circular RNAs (circRNAs) have been proposed as crucial regulators in IS. This study focused on the role of circPDS5B in IS and its underlying mechanism. Meth
Externí odkaz:
https://doaj.org/article/9d62a4c9cc774ee386b3fa8227636445
Akademický článek
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Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 304-318 (2022)
Nonsense-mediated mRNA decay (NMD) degrades transcripts with premature stop codons. Given the prevalence of nonsense single nucleotide polymorphisms (SNPs) in the general population, it is urgent to catalog the effects of clinically approved drugs on
Externí odkaz:
https://doaj.org/article/c5a7b47112fb4af6b175d6f12b4bd1df
Autor:
Jiacheng Cao, Xing Zhang, Penghui Xu, Haixiao Wang, Sen Wang, Lu Zhang, Zheng Li, Li Xie, Guangli Sun, Yiwen Xia, Jialun Lv, Jing Yang, Zekuan Xu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Gastric cancer (GC) is one of the most common malignant tumors worldwide. Currently, the overall survival rate of GC is still unsatisfactory despite progress in diagnosis and treatment. Therefore, studying the molecular mechanisms
Externí odkaz:
https://doaj.org/article/f0f514c6f5bd4bcb951203422580b34b
Autor:
Bingqiu Xiu, Yayun Chi, Lei Liu, Weiru Chi, Qi Zhang, Jiajian Chen, Rong Guo, Jing Si, Lun Li, Jingyan Xue, Zhi-Ming Shao, Zhao-Hui Wu, Shenglin Huang, Jiong Wu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-20 (2019)
Abstract Background The majority of breast cancer patients die of metastasis rather than primary tumors, whereas the molecular mechanisms orchestrating cancer metastasis remains poorly understood. Long noncoding RNAs (lncRNA) have been shown to regul
Externí odkaz:
https://doaj.org/article/d8113f2c63234be3b86df43c48562a53
Akademický článek
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Autor:
Yan Li, Bing Chen, Jingjing Zhao, Qin Li, Siyuan Chen, Tianan Guo, Yuchen Li, Hongyan Lai, Zhiao Chen, Zhiqiang Meng, Weijie Guo, Xianghuo He, Shenglin Huang
Publikováno v:
Advanced Science, Vol 8, Iss 13, Pp n/a-n/a (2021)
Abstract Circular RNAs (circRNAs) are an intriguing class of widely prevalent endogenous RNAs, the vast majority of which have not been characterized functionally. Here, we identified a novel oncogenic circRNA originating from the back‐splicing of
Externí odkaz:
https://doaj.org/article/ddfc2ac6a1654e1fa18e63b8d173cb84
Akademický článek
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