Zobrazeno 1 - 10
of 391
pro vyhledávání: '"HNRNPA1"'
Autor:
Yaoqi Sun, Bing Xiong, Xueqian Shuai, Jiale Li, Chunyan Wang, Jing Guo, Zhongping Cheng, Shupeng Liu
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Immunotherapies effectively treat human malignancies, but the low response and resistance are major obstacles. Neoantigen is an emerging target for tumor immunotherapy that can enhance anti-tumor immunity and improve immunotherapy
Externí odkaz:
https://doaj.org/article/39c966b21a2d41db9c1b36e6a360c9d9
Autor:
Shanshan Yu, Cheng Chen, Ming Chen, Jinxiao Liang, Kecheng Jiang, Bin Lou, Jun Lu, Xiaohua Zhu, Donghui Zhou
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-24 (2024)
Abstract Background Gastric cancer (GC) is associated with high mortality and heterogeneity and poses a great threat to humans. Gene therapies for the receptor tyrosine kinase RON and its spliceosomes are attracting increasing amounts of attention du
Externí odkaz:
https://doaj.org/article/02847291ffa646c38fd713dd7f0406c3
Publikováno v:
International Journal of Nanomedicine, Vol Volume 18, Pp 5943-5960 (2023)
Zhiyu Li,1 Zhongying Cao,1 Nanxi Li,2 Luying Wang,2 Cong Fu,2 Ran Huo,1,2 Guangqi Xu,2 Chonglin Tian,2,* Jianhai Bi1– 3,* 1Department of Plastic and Aesthetic Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong Univ
Externí odkaz:
https://doaj.org/article/7d57940f291948508c70f32bd2306717
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6825 (2024)
Biomolecular condensates (BMCs) exhibit physiological and pathological relevance in biological systems. Both liquid and solid condensates play significant roles in the spatiotemporal regulation and organization of macromolecules and their biological
Externí odkaz:
https://doaj.org/article/0c9ceec11a0f4c89ae670dbd5fee6052
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 10, Pp 517-530 (2023)
Ziyi Cao,1,* Li Guan,1,* Runzhi Yu,1 Fan Yang,2 Jie Chen1 1Department of Gastroenterology, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, People’s Republic of China; 2Shanghai Key Laboratory of Clinical Geriatric Medicin
Externí odkaz:
https://doaj.org/article/da41a48d52eb4557afde7a533fc9619f
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTHeterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) plays an important role in regulating the replication of many viruses. However, it remains elusive whether and how hnRNPA1 regulates fish virus replication. In this study, the effects of tw
Externí odkaz:
https://doaj.org/article/72212d3bdb4b4a608ad34f93fa6da0e6
Autor:
Liangyun Li, Shaoxi Diao, Zixiang Chen, Jintong Zhang, Wei Chen, Tianqi Wang, Xin Chen, Yuxin Zhao, Tao Xu, Cheng Huang, Jun Li
Publikováno v:
Pharmacological Research, Vol 193, Iss , Pp 106808- (2023)
Hepatic fibrosis is caused by liver damage as a consequence of wound healing response. Recent studies have shown that hepatic fibrosis could be effectively reversed, partly through regression of activated hepatic stellate cells (HSCs). Transcription
Externí odkaz:
https://doaj.org/article/2a8aff4b95084883a6b691edfd4d10e9
Autor:
Joseph P. Clarke, Patricia A. Thibault, Sakina Fatima, Hannah E. Salapa, Subha Kalyaanamoorthy, Aravindhan Ganesan, Michael C. Levin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The RNA binding protein heterogeneous nuclear ribonucleoprotein A1 (A1) regulates RNA metabolism, which is crucial to maintaining cellular homeostasis. A1 dysfunction mechanistically contributes to reduced cell viability and loss, but molecular mecha
Externí odkaz:
https://doaj.org/article/e9a6b9cc5b554f6ca0e0e99458443344
Publikováno v:
Non-Coding RNA, Vol 9, Iss 6, p 74 (2023)
Aging in women is accompanied by a dramatic change in circulating sex steroid hormones. Specifically, the primary circulating estrogen, 17β-estradiol (E2), is nearly undetectable in post-menopausal women. This decline is associated with a variety of
Externí odkaz:
https://doaj.org/article/fa87cd9c16a04159becb2734363afd83
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16214 (2023)
A dominant mutation in hnRNPA1 causes amyotrophic lateral sclerosis (ALS), but it is not known whether this mutation leads to motor neuron death through increased or decreased function. To elucidate the relationship between pathogenic hnRNPA1 mutatio
Externí odkaz:
https://doaj.org/article/9959ad069dce42dea3c2724443db0576