Higher Cerebrospinal Fluid Soluble Urokinase-type Plasminogen Activator Receptor, But Not Interferon γ-inducible Protein 10, Correlate With Higher Working Memory Deficits

Autor: De Almeida, Sergio M, Rotta, Indianara, Tang, Bin, Umlauf, Anya, Vaida, Florin, Cherner, Mariana, Franklin, Donald, Letendre, Scott, Ellis, Ronald J, HNRC Group

Publikováno v: Journal of acquired immune deficiency syndromes (1999), vol 90, iss 1

BackgroundWe hypothesized that the induction of monocyte activation biomarkers, especially soluble urokinase-type plasminogen activator receptor (suPAR) and interferon γ-inducible protein 10 (IP-10), is lower in HIV-1C than HIV-1B, owing to a defect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::9b664a714b7159b7cf054146e02baec9
https://escholarship.org/uc/item/2c98z3jt

HIV-1C and HIV-1B Tat protein polymorphism in Southern Brazil

Autor: de Almeida, Sérgio Monteiro, Rotta, Indianara, Vidal, Luine Rosele Renaud, Dos Santos, Jucelia Stadinicki, Nath, Avindra, Johnson, Kory, Letendre, Scott, Ellis, Ronald J, H. I. V. Neurobehavioral Research Center (HNRC) Group

Publikováno v: Journal of neurovirology, vol 27, iss 1

The transactivator of transcription (Tat) is a key HIV regulatory protein. We aimed to identify the frequency of key polymorphisms in HIV-1C compared with HIV-1B Tat protein, chiefly in the cysteine-, arginine-, and glutamine-rich domains and identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::b517a43191a9e4e768193c0a235fc653
https://escholarship.org/uc/item/1p6361z4

Blood amyloid-β protein isoforms are affected by HIV-1 in a subtype-dependent pattern

Autor: de Almeida, Sérgio M, Ribeiro, Clea E, Rotta, Indianara, Letendre, Scott, Potter, Michael, Tang, Bin, Batistela, Meiri, Vaida, Florin, Ellis, Ronald J, HIV Neurobehavioral Research Center (HNRC) Group

Publikováno v: Journal of neurovirology, vol 26, iss 1

This study aimed to compare serum amyloid processing biomarkers among HIV subtype B (n = 25), HIV subtype C (n = 26), healthy HIV-negative controls (n = 18), and patients with Alzheimer's disease (AD; n = 24). Immunoassays were used to measure main s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::79706621803363d7cd825ffb01cb13e4
https://escholarship.org/uc/item/7m82c49p

Neprilysin in the Cerebrospinal Fluid and Serum of Patients Infected With HIV1-Subtypes C and B

Autor: de Almeida, Sérgio M, Tang, Bin, Ribeiro, Clea E, Rotta, Indianara, Vaida, Florin, Piovesan, Mauro, Batistela Fernandes, Meire S, Letendre, Scott, Potter, Michael, Ellis, Ronald J, HIV Neurobehavioral Research Center (HNRC) Group

Publikováno v: Journal of acquired immune deficiency syndromes (1999), vol 78, iss 2

OBJECTIVE:Neprilysin (NEP) is the dominant Aβ peptide-degrading enzyme in the brain. HIV-1 subtype B transactivator of transcription protein is known to interfere with NEP function, but whether this is true of HIV-1C transactivator of transcription,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::18cfe1642690dc929601b160e8d8e11a
https://escholarship.org/uc/item/5c1583nm

Blood-CSF barrier and compartmentalization of CNS cellular immune response in HIV infection

Autor: de Almeida, Sérgio M, Rotta, Indianara, Ribeiro, Clea E, Smith, Davey, Wang, Ruiyi, Judicello, Jennifer, Potter, Michael, Vaida, Florin, Letendre, Scott, Ellis, Ronald J, HNRC Group

Publikováno v: de Almeida, SM; Rotta, I; Ribeiro, CE; Smith, D; Wang, R; Judicello, J; et al.(2016). Blood-CSF barrier and compartmentalization of CNS cellular immune response in HIV infection. JOURNAL OF NEUROIMMUNOLOGY, 301, 41-48. doi: 10.1016/j.jneuroim.2016.10.009. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5mf0q45h

HIV infection is persistent in the CNS, to evaluate the compartmentalization of the CNS immune response to HIV, we compared soluble markers of cellular immunity in the blood and CSF among HIV- (n=19) and HIV+ (n=68), as well as among HIV participants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::18027ae1a9f2aeac5d8663384a377ce6
https://escholarship.org/uc/item/5mf0q45h