Zobrazeno 1 - 8
of 8
pro vyhledávání: '"HNF4α, hepatocyte nuclear factor 4 alpha"'
Autor:
Liming Chen, Junjie Zhu, Lirong Zhang, Xiaochao Ma, Xueyan Shao, Pei Wang, Xiao-bo Zhong, Yifan Bao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 171-185 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obes
Autor:
Michelangelo Foti, Olivia Bejuy, Christine Maeder, Marta Correia de Sousa, Monika Gjorgjieva, Claudio De Vito, Laura Rubbia-Brandt, Dobrochna Dolicka, Margot Fournier, Cyril Sobolewski, Didier J. Colin, Flavien Berthou, Perry J. Blackshear
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology (2020)
Cellular and Molecular Gastroenterology and Hepatology (2020)
Background & Aims Tristetraprolin (TTP) is a key post-transcriptional regulator of inflammatory and oncogenic transcripts. Accordingly, TTP was reported to act as a tumor suppressor in specific cancers. Herein, we investigated how TTP contributes to
Autor:
Paul A. Dawson, Courtney B. Ferrebee
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 129-134 (2015)
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 129-134 (2015)
The classical functions of bile acids include acting as detergents to facilitate the digestion and absorption of nutrients in the gut. In addition, bile acids also act as signaling molecules to regulate glucose homeostasis, lipid metabolism and energ
Autor:
Yoshinori, Arisaka, Jun, Kobayashi, Kazuo, Ohashi, Kohei, Tatsumi, Kyungsook, Kim, Yoshikatsu, Akiyama, Masayuki, Yamato, Teruo, Okano
Publikováno v:
Regenerative Therapy
A heparin-modified thermoresponsive surface bound with heparin-binding epidermal growth factor-like growth factor (HB-EGF) was designed to allow creation of transferrable and functional hepatocyte sheets. A heparin-modified thermoresponsive surface w
Publikováno v:
Molecular Aspects of Medicine
Hepatobiliary bile salt (BS) transporters are critical determinants of BS homeostasis controlling intracellular concentrations of BSs and their enterohepatic circulation. Genetic or acquired dysfunction of specific transport systems causes intrahepat
Autor:
Wang P; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.; Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, CT 06269, USA., Shao X; Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, CT 06269, USA., Bao Y; Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, CT 06269, USA., Zhu J; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA., Chen L; Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, CT 06269, USA., Zhang L; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China., Ma X; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA., Zhong XB; Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, CT 06269, USA.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Jan; Vol. 10 (1), pp. 171-185. Date of Electronic Publication: 2019 Nov 28.
Autor:
Arisaka Y; Institute of Advanced Biomedical Engineering and Science and Global Center of Excellence (COE) Program, Tokyo Women's Medical University (TWIns), 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan., Kobayashi J; Institute of Advanced Biomedical Engineering and Science and Global Center of Excellence (COE) Program, Tokyo Women's Medical University (TWIns), 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan., Ohashi K; Institute of Advanced Biomedical Engineering and Science and Global Center of Excellence (COE) Program, Tokyo Women's Medical University (TWIns), 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan., Tatsumi K; Institute of Advanced Biomedical Engineering and Science and Global Center of Excellence (COE) Program, Tokyo Women's Medical University (TWIns), 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan., Kim K; Institute of Advanced Biomedical Engineering and Science and Global Center of Excellence (COE) Program, Tokyo Women's Medical University (TWIns), 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan., Akiyama Y; Institute of Advanced Biomedical Engineering and Science and Global Center of Excellence (COE) Program, Tokyo Women's Medical University (TWIns), 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan., Yamato M; Institute of Advanced Biomedical Engineering and Science and Global Center of Excellence (COE) Program, Tokyo Women's Medical University (TWIns), 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan., Okano T; Institute of Advanced Biomedical Engineering and Science and Global Center of Excellence (COE) Program, Tokyo Women's Medical University (TWIns), 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan.
Publikováno v:
Regenerative therapy [Regen Ther] 2016 Mar 26; Vol. 3, pp. 97-106. Date of Electronic Publication: 2016 Mar 26 (Print Publication: 2016).
Autor:
Ferrebee CB; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, GA 30322, USA ; Molecular Medicine Graduate Program, Wake Forest School of Medicine, Winston-Salem, NC 27153, USA., Dawson PA; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, GA 30322, USA.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2015 Mar; Vol. 5 (2), pp. 129-34. Date of Electronic Publication: 2015 Feb 20.