Zobrazeno 1 - 10
of 19
pro vyhledávání: '"HNF, Hepatocyte Nuclear Factor"'
Autor:
Gregory Tiao, Talita Ferreira Margues Aguiar, Alexander Bondoc, Soona Shin, Maria Prates Rivas, Michael E. Johnston, Ruhi Gulati, Meenasri Kumbaji, Ana Cristina Victorino Krepischi, James I. Geller, Lubov Timchenko, Nikolai Timchenko
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1669-1682 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1669-1682 (2021)
Background & Aims Epigenetic regulation of gene expression plays a critical role in the development of liver cancer; however, the molecular mechanisms of epigenetic-driven liver cancers are not well understood. The aims of this study were to examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1de4a5ee700fbcde5ea9b038cd2eb1
https://doi.org/10.1016/j.jcmgh.2021.06.026
https://doi.org/10.1016/j.jcmgh.2021.06.026
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 4, Iss 3, Pp 315-338 (2020)
Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Mayo Clinic Proceedings: Innovations, Quality & Outcomes
An understanding of the molecular basis of liver regeneration will open new horizons for the development of novel therapies for chronic liver failure. Such therapies would solve the drawbacks associated with liver transplant, including the shortage o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57f94c2b2aed8589dc105db85be58c0
http://www.sciencedirect.com/science/article/pii/S2542454820300394
http://www.sciencedirect.com/science/article/pii/S2542454820300394
Autor:
Mark R. Southern, M. Otrocka, Ulf Martens, Vicente Martínez-Redondo, Igor Cervenka, Bo Lundgren, Jorge C. Correia, Amanda T. Pettersson-Klein, Daniel Ferreira, Patrick R. Griffin, Theodore M. Kamenecka, A. Jenmalm-Jensen, Manizheh Izadi, Michael D. Cameron, Leandro Z. Agudelo, Jorge L. Ruas, Margareta Porsmyr-Palmertz
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 9, Iss, Pp 28-42 (2018)
Molecular Metabolism, Vol 9, Iss, Pp 28-42 (2018)
Objective The peroxisome proliferator-activated receptor-γ coactivator-1α1 (PGC-1α1) regulates genes involved in energy metabolism. Increasing adipose tissue energy expenditure through PGC-1α1 activation is potentially beneficial for systemic met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8adef5e0e4e4795105a62227894df6c
https://doi.org/10.1016/j.molmet.2018.01.017
https://doi.org/10.1016/j.molmet.2018.01.017
Autor:
Achim Weber, Svenja Debey-Pascher, Hamid Kashkar, Hildegard Büning, Ulrike Protzer, Gesa von Olshausen, JH Bockmann, Marc Ringelhan, Joachim L. Schultze, Martin F. Sprinzl, Marianna Hösel, Mathias Heikenwalder, Dennis Webb, Silke Arzberger, Maria Quasdorff
Publikováno v:
Cell. Mol. Gast. Hept. 4, 339-363 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 339-363 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 339-363 (2017)
Background & Aims The human hepatitis B virus (HBV) is a major cause of chronic hepatitis and hepatocellular carcinoma, but molecular mechanisms driving liver disease and carcinogenesis are largely unknown. We therefore studied cellular pathways alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2d142f4720604e77ddf16a5b0cdc55
https://doi.org/10.1016/j.jcmgh.2017.07.003
https://doi.org/10.1016/j.jcmgh.2017.07.003
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 6, Iss 5, Pp 413-425 (2016)
Acta Pharmaceutica Sinica B, Vol 6, Iss 5, Pp 413-425 (2016)
Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believed. The discovery of multiple important substrates of CYP2B6 as well as polymorphic differences has sparked increasing interest in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036909ac63a5f48e27936e5612f420e7
https://doi.org/10.1016/j.apsb.2016.07.016
https://doi.org/10.1016/j.apsb.2016.07.016
Autor:
Padma-Sheela Jayaraman, Abdenour Soufi
Publikováno v:
Biochemical Journal
The PRH (proline-rich homeodomain) [also known as Hex (haematopoietically expressed homeobox)] protein is a critical regulator of vertebrate development. PRH is able to regulate cell proliferation and differentiation and is required for the formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05a27873ad8853b0dbf1402f3628fec
http://europepmc.org/articles/PMC2570084
http://europepmc.org/articles/PMC2570084
Publikováno v:
The International Journal of Biochemistry & Cell Biology
Freshly isolated hepatocytes rapidly lose their differentiated properties when placed in culture. Therefore, production of a simple culture system for maintaining the phenotype of hepatocytes in culture would greatly facilitate their study. Our aim w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a15e9dbd990eea3d18bcfea5ca08ec5
https://doi.org/10.1016/j.biocel.2006.10.017
https://doi.org/10.1016/j.biocel.2006.10.017
Publikováno v:
Biochemical Pharmacology
Components of the renin-angiotensin system are well established targets for pharmacological intervention in a variety of disorders. Many such therapies abrogate the effects of the hypertensive and mitogenic peptide, angiotensin II, by antagonising it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc28a890fd84ce345fe3071d99bcbe4
https://pubmed.ncbi.nlm.nih.gov/17897633
https://pubmed.ncbi.nlm.nih.gov/17897633
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Akademický článek
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