Zobrazeno 1 - 10
of 1 041
pro vyhledávání: '"HNF, Hepatocyte Nuclear Factor"'
Autor:
Gregory Tiao, Talita Ferreira Margues Aguiar, Alexander Bondoc, Soona Shin, Maria Prates Rivas, Michael E. Johnston, Ruhi Gulati, Meenasri Kumbaji, Ana Cristina Victorino Krepischi, James I. Geller, Lubov Timchenko, Nikolai Timchenko
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1669-1682 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1669-1682 (2021)
Background & Aims Epigenetic regulation of gene expression plays a critical role in the development of liver cancer; however, the molecular mechanisms of epigenetic-driven liver cancers are not well understood. The aims of this study were to examine
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 4, Iss 3, Pp 315-338 (2020)
Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Mayo Clinic Proceedings: Innovations, Quality & Outcomes
An understanding of the molecular basis of liver regeneration will open new horizons for the development of novel therapies for chronic liver failure. Such therapies would solve the drawbacks associated with liver transplant, including the shortage o
Autor:
Mark R. Southern, M. Otrocka, Ulf Martens, Vicente Martínez-Redondo, Igor Cervenka, Bo Lundgren, Jorge C. Correia, Amanda T. Pettersson-Klein, Daniel Ferreira, Patrick R. Griffin, Theodore M. Kamenecka, A. Jenmalm-Jensen, Manizheh Izadi, Michael D. Cameron, Leandro Z. Agudelo, Jorge L. Ruas, Margareta Porsmyr-Palmertz
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 9, Iss, Pp 28-42 (2018)
Molecular Metabolism, Vol 9, Iss, Pp 28-42 (2018)
Objective The peroxisome proliferator-activated receptor-γ coactivator-1α1 (PGC-1α1) regulates genes involved in energy metabolism. Increasing adipose tissue energy expenditure through PGC-1α1 activation is potentially beneficial for systemic met
Autor:
Achim Weber, Svenja Debey-Pascher, Hamid Kashkar, Hildegard Büning, Ulrike Protzer, Gesa von Olshausen, JH Bockmann, Marc Ringelhan, Joachim L. Schultze, Martin F. Sprinzl, Marianna Hösel, Mathias Heikenwalder, Dennis Webb, Silke Arzberger, Maria Quasdorff
Publikováno v:
Cell. Mol. Gast. Hept. 4, 339-363 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 339-363 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 339-363 (2017)
Background & Aims The human hepatitis B virus (HBV) is a major cause of chronic hepatitis and hepatocellular carcinoma, but molecular mechanisms driving liver disease and carcinogenesis are largely unknown. We therefore studied cellular pathways alte
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 6, Iss 5, Pp 413-425 (2016)
Acta Pharmaceutica Sinica B, Vol 6, Iss 5, Pp 413-425 (2016)
Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believed. The discovery of multiple important substrates of CYP2B6 as well as polymorphic differences has sparked increasing interest in
Autor:
Rezaei, Naeimeh1 (AUTHOR), Dormiani, Kianoush1 (AUTHOR) k_dormiani@royaninstitute.org, Kiani-Esfahani, Abbas1 (AUTHOR), Mirdamadian, Somayeh1 (AUTHOR), Rahmani, Mohsen2 (AUTHOR), Jafarpour, Farnoosh2 (AUTHOR), Nasr-Esfahani, Mohammad Hossein1,2 (AUTHOR) mh.nasr-esfahani@royaninstitute.org
Publikováno v:
Scientific Reports. 11/5/2024, Vol. 14 Issue 1, p1-13. 13p.
Autor:
Serbis, Anastasios1,2,3 (AUTHOR) agalli@auth.gr, Kantza, Evanthia1 (AUTHOR) eksiomou@uoi.gr, Siomou, Ekaterini1 (AUTHOR), Galli-Tsinopoulou, Assimina3 (AUTHOR), Kanaka-Gantenbein, Christina4 (AUTHOR) chriskan@med.uoa.gr, Tigas, Stelios2 (AUTHOR)
Publikováno v:
International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10501. 18p.
Autor:
Padma-Sheela Jayaraman, Abdenour Soufi
Publikováno v:
Biochemical Journal
The PRH (proline-rich homeodomain) [also known as Hex (haematopoietically expressed homeobox)] protein is a critical regulator of vertebrate development. PRH is able to regulate cell proliferation and differentiation and is required for the formation
Publikováno v:
The International Journal of Biochemistry & Cell Biology
Freshly isolated hepatocytes rapidly lose their differentiated properties when placed in culture. Therefore, production of a simple culture system for maintaining the phenotype of hepatocytes in culture would greatly facilitate their study. Our aim w
Autor:
Yang, Xiaoyue1 (AUTHOR), Qiu, Kangli1 (AUTHOR), Jiang, Yaoyao1 (AUTHOR), Huang, Yumei1 (AUTHOR), Zhang, Yajuan1 (AUTHOR), Liao, Yunfei1 (AUTHOR) 2009xh0824@hust.edu.cn
Publikováno v:
International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 14, p7621. 30p.