Zobrazeno 1 - 10
of 101
pro vyhledávání: '"HMGCS1"'
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 5, Pp 330-336 (2024)
Background and objective Targeted therapies are ineffective in lung squamous cancer (LUSC), and the low response rate of immunotherapy hampers its application in LUSC, so it is urgent to explore new strategies for LUSC treatment. Ferroptosis plays an
Externí odkaz:
https://doaj.org/article/eda137930f034f97825a1f1de78a16a1
Autor:
Danyang Gu, Mujie Ye, Guoqin Zhu, Jianan Bai, Jinhao Chen, Lijun Yan, Ping Yu, Feiyu Lu, Chunhua Hu, Yuan Zhong, Pengfei Liu, Qibin He, Qiyun Tang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Pancreatic neuroendocrine neoplasms (pNENs) are relatively rare. Hypoxia and lipid metabolism-related gene acetyl-CoA synthetase 2 (ACSS2) is involved in tumor progression, but its role in pNENs is not revealed. This study showed
Externí odkaz:
https://doaj.org/article/9926ca8b5f3f40aeb1dbf272a4dadf8b
Akademický článek
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Autor:
Yunxia Dong, Chuwei Yu, Ningning Ma, Xiaoding Xu, Qian Wu, Henglei Lu, Likun Gong, Jing Chen, Jin Ren
Publikováno v:
Molecular Biomedicine, Vol 3, Iss 1, Pp 1-15 (2022)
Abstract Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driving factors in the transition from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH
Externí odkaz:
https://doaj.org/article/1954892f1a9048fc8f6f9164100c5411
Akademický článek
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Akademický článek
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Publikováno v:
Cancer Reports, Vol 5, Iss 9, Pp n/a-n/a (2022)
Abstract Background Emerging studies reveals that 3‐hydroxy‐3‐methylglutaryl‐CoA synthase 1 (HMGCS1) plays vital oncogenic roles in a broad spectrum of human cancers, but there is no pan‐cancer evidence on the relationship between HMGCS1 an
Externí odkaz:
https://doaj.org/article/23dc24f5e39c48a787b7294f5ee156b0
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Venetoclax is used for the priority treatment of elderly patients with acute myeloid leukemia (AML). Resistance or intolerance to venetoclax offsets its clinical benefits in some patients. Combination strategies with other drugs are promising alterna
Externí odkaz:
https://doaj.org/article/25361d7cb52945afa1f89b92e23d938a
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 2313-2331 (2020)
Cervical cancer is induced by persistent infections with high‐risk human papillomaviruses (HPVs), which produce the early protein 6 of HPVs (E6)/E7 protein that is involved in cell transformation by interacting with several oncoproteins or tumor su
Externí odkaz:
https://doaj.org/article/8e0e9292f453489b8a8304c19204a6d3
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background Colorectal cancer (CRC) is the fourth most deadly malignancy throughout the world. Extensive studies have shown that Krüppel-like factors (KLFs) play essential roles in cancer development. However, the function of KLF13 in CRC is
Externí odkaz:
https://doaj.org/article/ea12417fdd3e4bcd9ef01ed18ddfd808