Zobrazeno 1 - 10
of 41
pro vyhledávání: '"HMG PRINCEN"'
Autor:
Ulf Lindahl, Hmg Princen, El Lindstedt, M Voskuilen, Jwa van der Hoorn, Jan Oscarsson, Daniel Lindén, Mea Bekkers, Ralf Nilsson
Publikováno v:
British Journal of Pharmacology. 162:1553-1563
BACKGROUND AND PURPOSE Liver X receptor (LXR) agonists are atheroprotective but often induce hypertriglyceridaemia and liver steatosis. We investigated the effect of a novel high-affinity LXR activator, AZ876, on plasma lipids, inflammation and ather
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25b6da9ba026459cba8eea7824ee8477
https://doi.org/10.1111/j.1476-5381.2010.01168.x
https://doi.org/10.1111/j.1476-5381.2010.01168.x
Autor:
H. Jansen, Geesje M. Dallinga-Thie, Dali Study Grp, M.V. Huisman, Nicoline Hoogerbrugge, Hmg Princen, M.A. van de Ree, FV van Venrooij, Ronald P. Stolk, Ingrid I.L. Berk-Planken, Jan-Dirk Banga
Publikováno v:
Diabetes Care. 24:1335-1341
OBJECTIVE—In patients with type 2 diabetes, intensive glucose regulation, although effective for microangiopathy, has not been shown to have unambiguous preventive effects on the occurrence of cardiovascular disease. Patients with diabetes show a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad290ccf9a750f08e2e1058be9dccdc3
https://doi.org/10.2337/diacare.24.8.1335
https://doi.org/10.2337/diacare.24.8.1335
Publikováno v:
BMC News and views. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d9907d160070421ba133a74a7f86452
https://doi.org/10.1186/2048-4623-1-s2-014
https://doi.org/10.1186/2048-4623-1-s2-014
Publikováno v:
Web of Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91708a609d3305797855b989eaf7303d
https://doi.org/10.1016/s1567-5688(01)80183-5
https://doi.org/10.1016/s1567-5688(01)80183-5
Publikováno v:
University of Groningen
Biochemical Journal, 275, 501-505. PORTLAND PRESS LTD
Biochemical Journal, 275, 501-505. PORTLAND PRESS LTD
Bile acid synthesis, determined by conversion of [4-C-14]cholesterol into bile acids in rat and human hepatocytes and by measurement of mass production of bile acids in rat hepatocytes, was dose-dependently decreased by cyclosporin A, with 52% (rat)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7efc1f1b67506c954d381bd4b5264a67
https://research.rug.nl/en/publications/1e236b33-d992-4791-a19f-88fbe6648926
https://research.rug.nl/en/publications/1e236b33-d992-4791-a19f-88fbe6648926
Publikováno v:
University of Groningen
The Journal of Clinical Investigation, 78(4), 1064-1071. AMER SOC CLINICAL INVESTIGATION INC
The Journal of Clinical Investigation, 78(4), 1064-1071. AMER SOC CLINICAL INVESTIGATION INC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d468d8aaf1778846baed10aaf5d4ef9
https://research.rug.nl/en/publications/597e6635-40c0-45bb-b2c9-39d09e8822e2
https://research.rug.nl/en/publications/597e6635-40c0-45bb-b2c9-39d09e8822e2
Autor:
Inia JA; Department of Metabolic Health Research, The Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.; Department of Cardiology, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, The Netherlands., Attema J; Department of Metabolic Health Research, The Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., de Ruiter C; Department of Metabolic Health Research, The Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Menke AL; Department of Metabolic Health Research, The Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Caspers MPM; Department of Microbiology and Systems Biology, TNO, Leiden, The Netherlands., Verschuren L; Department of Microbiology and Systems Biology, TNO, Leiden, The Netherlands., Wilson M; Genentech Inc., South San Francisco, California, USA., Arlantico A; Translational Immunology, Genentech Inc., South San Francisco, California, USA., Brightbill HD; Translational Immunology, Genentech Inc., South San Francisco, California, USA., Jukema JW; Department of Cardiology, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, The Netherlands.; Netherlands Heart Institute, Utrecht, The Netherlands., van den Hoek AM; Department of Metabolic Health Research, The Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Princen HMG; Department of Metabolic Health Research, The Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Chen MZ; Translational Immunology, Genentech Inc., South San Francisco, California, USA., Morrison MC; Department of Metabolic Health Research, The Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Oct 31; Vol. 38 (20), pp. e70087.
Autor:
Inia JA; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.; Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, The Netherlands., de Jong JCBC; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.; Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands., Keijzer N; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Menke AL; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Princen HMG; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, The Netherlands.; Netherlands Heart Institute, Utrecht, The Netherlands., van den Hoek AM; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Apr 15; Vol. 38 (7), pp. e23579.
Autor:
Westerhout J; TNO Risk Analysis for Products in Development, 3584 CB Utrecht, The Netherlands., den Heijer-Jordaan A; TNO Risk Analysis for Products in Development, 3584 CB Utrecht, The Netherlands., Princen HMG; TNO Metabolic Health Research, 2333 BE Leiden, The Netherlands., Stierum R; TNO Risk Analysis for Products in Development, 3584 CB Utrecht, The Netherlands.
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2024 Mar 26; Vol. 198 (2), pp. 191-209.
Autor:
van Gemert Y; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., Blom AB; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., Di Ceglie I; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., Walgreen B; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., Helsen M; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., Sloetjes A; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., Vogl T; Institute of Immunology, University of Münster, Germany., Roth J; Institute of Immunology, University of Münster, Germany., Kruisbergen NNL; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., Pieterman EJ; Metabolic Health Research, TNO, Leiden, the Netherlands., Princen HMG; Metabolic Health Research, TNO, Leiden, the Netherlands., van der Kraan PM; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., van Lent PLEM; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands., van den Bosch MHJ; Experimental Rheumatology, Radboud university medical center, Nijmegen, the Netherlands. Electronic address: martijn.vandenbosch@radboudumc.nl.
Publikováno v:
Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2023 Jul; Vol. 31 (7), pp. 934-943. Date of Electronic Publication: 2023 Mar 08.