Melatonin attenuates pulmonary hypertension in chronically hypoxic rats

Autor: George L. Tipoe, Man-Lung Fung, Chi Fai Lau, MW Hung, Angela Ming See Poon, HM Yeung

Publikováno v: International Journal of Molecular Sciences; Volume 18; Issue 6; Pages: 1125
International Journal of Molecular Sciences

Chronic hypoxia induces pulmonary hypertension and vascular remodeling, which are clinically relevant to patients with chronic obstructive pulmonary disease (COPD) associated with a decreased level of nitric oxide (NO). Oxidative stress and inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d6ed1a913860a873ec79071f773f3d
http://hdl.handle.net/10722/244666

Chronic intermittent hypoxia alters Ca2+handling in rat cardiomyocytes by augmented Na+/Ca2+exchange and ryanodine receptor activities in ischemia-reperfusion

Autor: Gennadi M. Kravtsov, Tak Ming Wong, Kwong Man Ng, Man-Lung Fung, HM Yeung

Publikováno v: American Journal of Physiology-Cell Physiology. 292:C2046-C2056

This study examined Ca2+handling mechanisms involved in cardioprotection induced by chronic intermittent hypoxia (CIH) against ischemia-reperfusion (I/R) injury. Adult male Sprague-Dawley rats were exposed to 10% inspired O2continuously for 6 h daily

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e919b3e7fdcd28b305fc52487e2aa686
https://doi.org/10.1152/ajpcell.00458.2006

Cardioprotective effects of melatonin against myocardial injuries induced by chronic intermittent hypoxia in rats

Autor: Man-Lung Fung, MW Hung, HM Yeung, Chi-Fai Lau

Publikováno v: Journal of pineal research. 58(1)

Obstructive sleep apnea (OSA) associated with chronic intermittent hypoxia (CIH) increases the morbidity and mortality of ischemic heart disease in patients. Yet, there is a paucity of preventive measures targeting the pathogenesis of CIH-induced myo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2ac99fa407d4ff17bb968fab569824
https://pubmed.ncbi.nlm.nih.gov/25369321

Creutzfeldt-Jakob disease in Hong Kong

Autor: K KP, Ng, P CK, Li, C K, Wong, J HM, Chan, J HM, Yeung, K T, Loo

Publikováno v: Hong Kong medical journal = Xianggang yi xue za zhi. 3(4)

Two elderly patients presented with rapidly progressive dementia and their electroencephalograms showed periodic discharges. Creutzfeldt-Jakob disease was pathologically confirmed in one of the patients. Striking clinical features and characteristic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ddf057c70401107346b3a5783cd3c892
https://pubmed.ncbi.nlm.nih.gov/11847399

High dose opioid agonist therapy for patients with opioid use disorder: a case series exploring this patient-centered approach.

Autor: Nigam P; Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Marx J; Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Olasimbo O; Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Induru V; Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Yeung HM; Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.

Publikováno v: Journal of addictive diseases [J Addict Dis] 2024 Sep 02, pp. 1-8. Date of Electronic Publication: 2024 Sep 02.