Zobrazeno 1 - 10
of 779
pro vyhledávání: '"HLA-alleles"'
Autor:
Raya Saleh, Erik Sundberg, Mia Olsson, Katarina Tengvall, Lars Alfredsson, Ingrid Kockum, Leonid Padyukov, Helena Erlandsson Harris
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Juvenile Idiopathic Arthritis (JIA) is a complex autoimmune disease and the most common chronic rheumatological disease affecting children under the age of 16. The etiology of JIA remains poorly understood, but evidence suggests a
Externí odkaz:
https://doaj.org/article/d8bc63d7b96a48848186f553c014605d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Cephalosporin antibiotics are widely used in clinical settings, but they can cause hypersensitivity reactions, which may be influenced by genetic factors such as the expression of Human leukocyte antigen (HLA) molecules. This study aimed to
Externí odkaz:
https://doaj.org/article/0dff0a96766f4e4f968fa068d8bb5bf1
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionThe immune response after transplantation depends on recipient/donor HLA allele mismatches. To enhance our understanding of the relations of HLA alleles in terms of amino-acid polymorphisms and shared epitopes, we assessed pairwise sequen
Externí odkaz:
https://doaj.org/article/4f7a464fc14c40f6bac9c4420c5fa791
Autor:
Irin Vichara-anont, Lalita Lumkul, Settawut Taratikhundej, Manop Pithukpakorn, Ekkapong Roothumnong, Chamard Wongsa, Thanachit Krikeerati, Aree Jameekornrak Taweechue, Orathai Theankeaw, Nathachit Limjunyawong, Nitat Sookrung, Torpong Thongngarm, Mongkhon Sompornrattanaphan
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32787- (2024)
Background: Banana allergy is on the rise in tropical regions. Advances in genomics and candidate gene identification have increased interest in genetic factors in food allergies. However, the genetic basis of IgE-mediated banana allergy is underexpl
Externí odkaz:
https://doaj.org/article/0b0ebe400a644db3a50a60dc5bc3c849
Autor:
Ioanna Diamanti, Asimina Fylaktou, Evgenia Verrou, Efthimia Vlachaki, Manolis Sinakos, Eirini Katodritou, Konstantinos Ouranos, Fani Minti, Georgia Gioula
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionHuman leukocyte antigen (HLA) polymorphisms have been associated with the development of various autoimmune diseases, as well as malignant neoplasms. Non-Hodgkin lymphomas (NHLs) are a heterogenous group of lymphoid malignancies in which
Externí odkaz:
https://doaj.org/article/2f2c1083e320444aaf55b36bf7838088
Autor:
Farhad Abolnezhadian, Sara Iranparast, Mojtaba Shohan, Zahra Shokati Eshkiki, Mahtab Hamed, Maryam Seyedtabib, Roohangiz Nashibi, Mohammad-Ali Assarehzadegan, Seyed Ali Mard, Ali Akbar Shayesteh, Niloofar Neisi, Manoochehr Makvandi, Seyed Mohammad Alavi, Gholamreza Shariati
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28528- (2024)
Background: Severe acute respiratory syndrome coronavirus 2 was first reported in December 2019 and it has spread globally ever since. The HLA system is crucial in directing anti-viral immunity and recent studies are investigating the possible involv
Externí odkaz:
https://doaj.org/article/afa25566f62e44e9a5a19d1cb16e2263
Autor:
Ormandjieva A., Ivanova M.
Publikováno v:
Acta Medica Bulgarica, Vol 50, Iss 3, Pp 11-17 (2023)
The Human Major Histocompatibility Complex (HLA) is the most polymorphic region of the human genome and encodes molecules with a central role in antigen-specific immune responses. Class I and class II HLA genes have an important role in bone marrow a
Externí odkaz:
https://doaj.org/article/f0274b54dfcb44458bc7bea09c5f957c
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background COVID-19 is a respiratory disease caused by a novel coronavirus called as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Detected for the first time in December 2019 in Wuhan and it has quickly spread all over the w
Externí odkaz:
https://doaj.org/article/f4de84a7ffc54c7e8df4c295d6be9133
Publikováno v:
Медицинская иммунология, Vol 24, Iss 5, Pp 1047-1056 (2022)
Efficacy of search for the unrelated compatible transplant donors depends on a number of factors. Of most importance are the standards of primary HLA typing, and the immunogenetic diversity of the donor pool. Timely donor selection guarantees the opt
Externí odkaz:
https://doaj.org/article/429fc1300484493b8a9c2b83d4afc204
Autor:
Johanna Classon, Margherita Zamboni, Camilla Engblom, Kanar Alkass, Giulia Mantovani, Christian Pou, Dieudonné Nkulikiyimfura, Petter Brodin, Henrik Druid, Jeff Mold, Jonas Frisén
Publikováno v:
Molecular Oncology, Vol 16, Iss 19, Pp 3452-3464 (2022)
Prostate cancer is a heterogeneous disease with a need for new prognostic biomarkers. Human leukocyte antigen (HLA) genes are highly polymorphic genes central to antigen presentation to T‐cells. Two alleles, HLA‐A*02:01 and HLA‐A*24:02, have be
Externí odkaz:
https://doaj.org/article/9acb7be2d0f6479d879f6f4a25f54423