Zobrazeno 1 - 10
of 236
pro vyhledávání: '"HLA-DQ8"'
Autor:
Shareen Forbes, Anne Halpin, Anna Lam, Don Grynoch, Richard Parker, Luis Hidalgo, David Bigam, Blaire Anderson, Khaled Dajani, Tatsuya Kin, Doug O'Gorman, Peter A. Senior, Patricia Campbell, A.M. James Shapiro
Publikováno v:
EClinicalMedicine, Vol 67, Iss , Pp 102333- (2024)
Summary: Background: In solid organ transplantation, HLA matching between donor and recipient is associated with superior outcomes. In islet transplantation, an intervention for Type 1 diabetes, HLA matching between donor and recipient is not perform
Externí odkaz:
https://doaj.org/article/0b2972dd9f5648268b9c64e922467b66
Publikováno v:
Genetics & Applications, Vol 7, Iss 2 (2023)
Celiac disease (CD) is an autoimmune disease characterized by gluten intolerance. The main cause of this immune - mediated enteropathy is gluten, a protein mainly present in wheat, rye, barley and spelt. The predisposition to celiac disease is determ
Externí odkaz:
https://doaj.org/article/bb2f050b21424f05ae5a4a42ca632187
Publikováno v:
Allergies, Vol 3, Iss 1, Pp 39-57 (2023)
Celiac peptide-generating α- and γ-gliadins consist of a disordered N-terminal domain extended by an α-helical-folded C-terminal domain. Celiac peptides, primarily located along the disordered part of α- and γ-gliadin molecules, are nicely expos
Externí odkaz:
https://doaj.org/article/4942d0587fac495281b8ecd20cb5b0b1
Autor:
Sandrine Luce, Sophie Guinoiseau, Alexis Gadault, Franck Letourneur, Patrick Nitschke, Marc Bras, Michel Vidaud, Pierre Charneau, Etienne Larger, Maikel L. Colli, Decio L. Eizirik, François Lemonnier, Christian Boitard
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
To circumvent the limitations of available preclinical models for the study of type 1 diabetes (T1D), we developed a new humanized model, the YES-RIP-hB7.1 mouse. This mouse is deficient of murine major histocompatibility complex class I and class II
Externí odkaz:
https://doaj.org/article/6206b24d7ab14e419c5c8a08cad4d3d1
Akademický článek
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Akademický článek
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Publikováno v:
Allergies
Volume 3
Issue 1
Pages: 39-57
Volume 3
Issue 1
Pages: 39-57
Celiac peptide-generating α- and γ-gliadins consist of a disordered N-terminal domain extended by an α-helical-folded C-terminal domain. Celiac peptides, primarily located along the disordered part of α- and γ-gliadin molecules, are nicely expos
Publikováno v:
The Saudi Journal of Gastroenterology, Vol 24, Iss 5, Pp 268-273 (2018)
Background/Aim: To determine the frequency of celiac disease (CD)-predisposing human leukocyte antigen (HLA)-DQ genotypes in the Saudi population, where the prevalence of CD is 1.5% as recently reported in a mass screening study. Patients and Methods
Externí odkaz:
https://doaj.org/article/a1c9e4439a2e45a8af85ff7720adabae
Autor:
Hema Sharma, Claire E. Turner, Matthew K. Siggins, Mona El-Bahrawy, Bruno Pichon, Angela Kearns, Shiranee Sriskandan
Publikováno v:
mSphere, Vol 4, Iss 5 (2019)
ABSTRACT Nonmenstrual toxic shock syndrome (nmTSS), linked to TSST-1-producing CC30 Staphylococcus aureus, is the leading manifestation of toxic shock syndrome (TSS). Due to case rarity and a lack of tractable animal models, TSS pathogenesis is poorl
Externí odkaz:
https://doaj.org/article/82173a6aae1d488ab7997188d3224846
Autor:
Karim Mowla, Najmeh Ahmadzadeh Goli, Reza Kazemi Nezhad, Zeinab Deris Zayeri, Mehrdad Dargahi Mal-Amir, Elham Rajaei
Publikováno v:
Russian Open Medical Journal, Vol 8, p e0108 (2019)
Background ― Rheumatoid arthritis (RA) is an inflammatory, autoimmune disease induced by certain auto-antigens. HLA-DRB1*0401 allele has a significant relationship with RA incident. Additionally, DQβ1*0301, *302(DQ8), *303, and *304 can increase R
Externí odkaz:
https://doaj.org/article/260274334e7b4de6bea3e7423f88fb5c