Zobrazeno 1 - 10
of 305
pro vyhledávání: '"HK Muller"'
Autor:
HK Muller, QP Wu, Yuichiro Itoh, Lorena Rivera, KhE Chen, Arthur P. Arnold, Mrinal K. Ghosh, KC Radecki, Ameae M. Walker, Lisa Ma, Tomohiro Yonezawa, R Dill-Garlow
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
We have used the four core genotypes (FCG) mouse model, which allows a distinction between effects of gonadal secretions and chromosomal complement, to determine when sex differences in the immune system first appear and what influences their develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84f07c815886b7ff614709fde5fd072
https://doi.org/10.3389/fendo.2021.582614
https://doi.org/10.3389/fendo.2021.582614
Autor:
Daniel J Tan, Eugene Haydn Walters, Mathew Suji Eapen, S Weston, Chris Ward, Kielan Darcy McAlinden, HK Muller, Sukhwinder Singh Sohal
Publikováno v:
Respirology. 22:1125-1132
Background and objective The objective of this study was to enumerate total cells and the number of inflammatory cell differentials in large airways (LAs) versus small airways (SAs) of mild-moderate COPD, and against appropriate controls. Methods For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9586eb144e4b83bffa9ec0923c96dea4
https://doi.org/10.1111/resp.13021
https://doi.org/10.1111/resp.13021
Autor:
Chris Ward, David W. Reid, Malik Quasir Mahmood, Darryl A. Knight, Sukhwinder Singh Sohal, HK Muller, Eugene Haydn Walters
Publikováno v:
Respirology. 22:133-140
Background and objective COPD is characterized by poorly reversible airflow obstruction usually due to cigarette smoking. Transforming growth factor (TGF)-β1 has been implicated in the pathogenesis of COPD, and in particular a process called epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74397b71dca0222b0a533818581d1fd5
https://doi.org/10.1111/resp.12882
https://doi.org/10.1111/resp.12882
Publikováno v:
Respirology. 21:504-510
Background and objective PAFr is a cell adhesion site for specific bacteria, notably non-typeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae. We previously published that PAFr expression is significantly upregulated in the large airwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb1afc8c68606894f763f73aacfd5e0
https://doi.org/10.1111/resp.12709
https://doi.org/10.1111/resp.12709
Publikováno v:
Oncogene. 35:3342-3350
Ultraviolet radiation (UVR) exposure increases malignant melanoma (MM) risk, but in the context of acute, not cumulative exposure. CT and CCTT changes make up the overwhelming majority of single base substitutions (SBS) in MM DNA, as both precursor m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce93f89d253907293d565f4c6085576
https://doi.org/10.1038/onc.2015.386
https://doi.org/10.1038/onc.2015.386
Autor:
Chris Ward, Sukhwinder Singh Sohal, HK Muller, Eugene Haydn Walters, Steve Weston, Shakti D. Shukla, Malik Quasir Mahmood
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
COPD is characterised by poorly reversible airflow obstruction usually due to cigarette smoking. The transcription factor clusters of β-catenin/Snail1/Twist has been implicated in the process of epithelial mesenchymal transition (EMT), an intermedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7f49ebf1fb07d98290ace78677e2ac
https://hdl.handle.net/10453/161757
https://hdl.handle.net/10453/161757
Autor:
Gregory J. Walker, Herlina Y. Handoko, Ramesh Ram, Grant Morahan, HK Muller, Blake Ferguson, Pamela Mukhopadhyay, H.P. Soyer
Publikováno v:
Oncogene. 34:2879-2886
Susceptibility to most common cancers is likely to involve interaction between multiple low risk genetic variants. Although there has been great progress in identifying such variants, their effect on phenotype and the mechanisms by which they contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20321ff847c77705dd66a502ff66752b
https://doi.org/10.1038/onc.2014.227
https://doi.org/10.1038/onc.2014.227
Publikováno v:
Photochemical & Photobiological Sciences. 12:536-545
Ultraviolet B (UVB) irradiation of the skin has the benefit of causing the local production of previtamin D3 but also results in cutaneous DNA damage and suppression of the skin immune system (SIS). Strains of mice differ in their ability to be suppr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1460bc22ecc54f1677a894963555a5ac
https://doi.org/10.1039/c2pp25211b
https://doi.org/10.1039/c2pp25211b
Publikováno v:
Medical oncology (Northwood, London, England). 34(3)
NSCLC is a leading cause of morbidity and mortality worldwide. It includes adeno- and squamous cell carcinoma. In the background, COPD and smoking play a vital role in development of NSCLC. Local progression and metastasis of NSCLC has been associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f60cca76f22f42fde950062728afbb9
https://pubmed.ncbi.nlm.nih.gov/28197929
https://pubmed.ncbi.nlm.nih.gov/28197929
Autor:
HK Muller, R Latham, Sukhwinder Singh Sohal, S Weston, Shakti D. Shukla, Eugene Haydn Walters, Malik Quasir Mahmood
Publikováno v:
Respiratory Research
Background ICAM-1 is a major receptor for ~60% of human rhinoviruses, and non-typeable Haemophilus influenzae, two major pathogens in COPD. Increased cell-surface expression of ICAM-1 in response to tobacco smoke exposure has been suggested. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f220a434ca59e91b8b8a290a4b7cb7b
https://hdl.handle.net/10453/162303
https://hdl.handle.net/10453/162303