Výsledky vyhledávání - "HIV-human immunodeficiency virus"

Akademický článek

An Overview Review of Understanding the Need for Adolescents Sexual and Reproductive Health Interventions

Publikováno v: Human Research in Rehabilitation, Vol 14, Iss 1, Pp 193-207 (2024)

Adolescents are the most vulnerable group, who are denied to access information and guidance related to sexual and reproductive health needs because of the social taboos that lead them to encumbrances. This review study helps to understand the diff

Externí odkaz: https://doaj.org/article/b61d3604c11243a091d4ea09208a378f

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Akademický článek

SWIFT clustering analysis of intracellular cytokine staining flow cytometry data of the HVTN 105 vaccine trial reveals high frequencies of HIV-specific CD4+ T cell responses and associations with humoral responses

Autor: Tim R. Mosmann, Jonathan A. Rebhahn, Stephen C. De Rosa, Michael C. Keefer, M. Juliana McElrath, Nadine G. Rouphael, Giuseppe Pantaleo, Peter B. Gilbert, Lawrence Corey, James J. Kobie, Juilee Thakar

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionThe HVTN 105 vaccine clinical trial tested four combinations of two immunogens - the DNA vaccine DNA-HIV-PT123, and the protein vaccine AIDSVAX B/E. All combinations induced substantial antibody and CD4+ T cell responses in many participa

Externí odkaz: https://doaj.org/article/52dd5afd41534ef9921ac84b943b0929

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Akademický článek

HIV seroconversion and associated factors among seronegative pregnant women attending ANC in Ethiopia: an institution-based cross-sectional study

Autor: Dawit Sisay Dessale, Mulugeta Betre Gebremariam, Asrat Arja Wolde

Publikováno v: Frontiers in Reproductive Health, Vol 6 (2024)

BackgroundIn countries with limited resources, including Ethiopia, HIV is diagnosed using a rapid serological test, which does not detect the infection during the window period. Pregnant women who test negative for HIV on the first test may seroconve

Externí odkaz: https://doaj.org/article/7fd5dcdc9bd845f1abd6e84bf873740f

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Akademický článek

Prevalence of resistance-associated viral variants to the HIV-specific broadly neutralising antibody 10-1074 in a UK bNAb-naïve population

Autor: Panagiota Zacharopoulou, Ming Lee, Thiago Oliveira, John Thornhill, Nicola Robinson, Helen Brown, Sabine Kinloch, Philip Goulder, Julie Fox, Sarah Fidler, M. Azim Ansari, John Frater

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Broadly neutralising antibodies (bNAbs) targeting HIV show promise for both prevention of infection and treatment. Among these, 10-1074 has shown potential in neutralising a wide range of HIV strains. However, resistant viruses may limit the clinical

Externí odkaz: https://doaj.org/article/64915d7639e0415280ddaf032c59335a

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Akademický článek

Editorial: Viral escape of mucosal immunity in sexually transmitted diseases

Autor: Elena Criscuolo, Francesca Pala, Gabriel Siracusano, Assunta Venuti

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Externí odkaz: https://doaj.org/article/a86ec0d006c54d9bb8cad1a6f93b9b62

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Akademický článek

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Akademický článek

A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors

Autor: Meredith E. Davis-Gardner, Jesse A. Weber, Jun Xie, Katja Pekrun, Eric A. Alexander, Kim L. Weisgrau, Jessica R. Furlott, Eva G. Rakasz, Mark A. Kay, Guangping Gao, Michael Farzan, Matthew R. Gardner

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionUse of adeno-associated virus (AAV) vectors is complicated by host immune responses that can limit transgene expression. Recent clinical trials using AAV vectors to deliver HIV broadly neutralizing antibodies (bNAbs) by intramuscular admi

Externí odkaz: https://doaj.org/article/00463782da80486d88a3fbab8e5a811b

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Akademický článek

Immune activation and exhaustion marker expression on T-cell subsets in ART-treated adolescents and young adults with perinatal HIV-1 infection as correlates of viral persistence

Autor: Yuyang Huang, Adit Dhummakupt, Priya Khetan, Tricia Nilles, Weiqiang Zhou, Prakriti Mudvari, Joseph Szewczyk, Ya Hui Chen, Eli Boritz, Hongkai Ji, Allison Agwu, Deborah Persaud

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

HIV-1 infection in memory CD4+ T cells forms a latent reservoir that is a barrier to cure. Identification of immune biomarkers that correlate with HIV-1 reservoir size may aid with evaluating efficacy of HIV-1 eradication strategies, towards ART-free

Externí odkaz: https://doaj.org/article/0ad620a430c64a5aae256651e3266a4a

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Akademický článek

Measuring the impact of COVID-19 social distancing measures on sexual health behaviours and access to HIV and sexual and reproductive health services for people living with HIV in Botswana

Autor: Samuel Ensor, Imogen Mechie, Rebecca Ryan, Aamirah Mussa, Bame Bame, Lefhela Tamuthiba, Neo Moshashane, Chelsea Morroni

Publikováno v: Frontiers in Global Women's Health, Vol 4 (2023)

IntroductionUninterrupted access to HIV and sexual and reproductive health (SRH) services is essential, particularly in high HIV prevalence settings, to prevent unintended pregnancy and vertical HIV transmission. Understanding the challenges that COV

Externí odkaz: https://doaj.org/article/2cc24bfc2c644c58b89362bb3d51e60b

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