Zobrazeno 1 - 10
of 74
pro vyhledávání: '"HIV-entry inhibitor"'
Autor:
Shalini Yadav, Vishnudatt Pandey, Rakesh Kumar Tiwari, Rajendra Prasad Ojha, Kshatresh Dutta Dubey
Publikováno v:
Molecules, Vol 26, Iss 1, p 239 (2021)
CD4-mimetic HIV-1 entry inhibitors are small sized molecules which imitate similar conformational flexibility, in gp120, to the CD4 receptor. However, the mechanism of the conformational flexibility instigated by these small sized inhibitors is littl
Externí odkaz:
https://doaj.org/article/9b1108e3fdfd451ab4f991f18d98c0b6
Autor:
Xuanxuan Zhang, Jinquan Chen, Fei Yu, Chunyan Wang, Ruxia Ren, Qian Wang, Suiyi Tan, Shibo Jiang, Shuwen Liu, Lin Li
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Several studies have reported that amyloid fibrils in human semen formed from a naturally occurring peptide fragment of prostatic acidic phosphatase (PAP248-286), known as semen-derived enhancer of viral infection (SEVI), could dramatically enhance h
Externí odkaz:
https://doaj.org/article/d0f15b71ae3f4d82a3f7bf15554a1477
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This paper characterizes a d-peptide HIV entry inhibitor, CPT31, in rhesus macaques. This nonhuman primate animal model provides the most robust evaluation of an in vivo antiviral prior to human trials. As described here, CPT31 is a prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::312fda894949d6b46374adce207eb52a
https://pubmed.ncbi.nlm.nih.gov/32820072
https://pubmed.ncbi.nlm.nih.gov/32820072
Publikováno v:
Molecules, Vol 26, Iss 239, p 239 (2021)
Molecules
Volume 26
Issue 1
Molecules
Volume 26
Issue 1
CD4-mimetic HIV-1 entry inhibitors are small sized molecules which imitate similar conformational flexibility, in gp120, to the CD4 receptor. However, the mechanism of the conformational flexibility instigated by these small sized inhibitors is littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69df095d016555cf047057f0b6fa2b26
https://doi.org/10.3390/molecules26010239
https://doi.org/10.3390/molecules26010239
Akademický článek
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Akademický článek
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Autor:
Raymond C. Stevens, Vadim Cherezov, Gye Won Han, Tracy M. Handel, Yi Zheng, Beili Wu, Ruben Abagyan, Irina Kufareva
Publikováno v:
Immunity, vol 46, iss 6
Summary CCR5 is the primary chemokine receptor utilized by HIV to infect leukocytes, whereas CCR5 ligands inhibit infection by blocking CCR5 engagement with HIV gp120. To guide the design of improved therapeutics, we solved the structure of CCR5 in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b398ad4f3e2e393251e81dee991d9306
https://escholarship.org/uc/item/0q3240rb
https://escholarship.org/uc/item/0q3240rb
Publikováno v:
Biochemical Journal
Lipid-conjugated peptides have advanced the understanding of membrane protein functions and the roles of lipids in the membrane milieu. These lipopeptides modulate various biological systems such as viral fusion. A single function has been suggested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6201004eb74f7b94a76c1de16a516874
http://europepmc.org/articles/PMC4072049
http://europepmc.org/articles/PMC4072049
Autor:
Lu, Yunyu
Ce travail de thèse a pour objectif la simplification de la préparation d’un nouveau type d’inhibiteur d’entrée du VIH conçu, synthétisé et validé dans le cadre d’une collaboration entre le laboratoire, l’Institut de Biologie Structu
Externí odkaz:
http://www.theses.fr/2016SACLS553/document
Autor:
Lu, Yunyu
Publikováno v:
Chimie organique. Université Paris Saclay (COmUE), 2016. Français. ⟨NNT : 2016SACLS553⟩
This work aims at simplifying the preparation of a new type of HIV entry inhibitor, conceived, synthesized and validated within a collaboration between our group, the "Institut de Biologie Structurale" (Grenoble) and the Institut Pasteur (Paris). Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a0b87b8848f371bf2a4f0e629de49756
https://tel.archives-ouvertes.fr/tel-01415629
https://tel.archives-ouvertes.fr/tel-01415629