Zobrazeno 1 - 10
of 1 216
pro vyhledávání: '"HIV-associated neurocognitive disorder"'
Autor:
Esther Maboso Ekolo, Aimée Masaya Mupuala, Joseph Mabiala Bodi, Adolphine Nkuadiolandu, Pierre Manyanga Tshibasu
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Objectives HIV-infected individuals are at increased risk of neurocognitive disorders compared with the general population. Studies suggest that, despite the combination of antiretroviral drugs, HIV infection causes immune activation leading
Externí odkaz:
https://doaj.org/article/99a699cd42304ce2839471b921169a16
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5530-5549 (2024)
A large portion of patients with Human Immunodeficiency Virus (HIV) have neurologic sequelae. Those with better-controlled HIV via antiretroviral therapies generally have less severe neurologic symptoms. However, for many patients, antiretrovirals do
Externí odkaz:
https://doaj.org/article/cf1fb494a1a64a4799c602eccdd6e2d0
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundHIV can invade the central nervous system (CNS) early during infection, invading perivascular macrophages and microglia, which, in turn, release viral particles and immune mediators that dysregulate all brain cell types. Consequently, child
Externí odkaz:
https://doaj.org/article/bcc606d7a97e4ec6bc3d1ac6c38a3e78
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundDespite the widespread adoption of combination antiretroviral therapy (cART) in managing HIV, the virus’s impact on the brain structure of patients remains significant. This study aims to longitudinally explore the persistent effects of H
Externí odkaz:
https://doaj.org/article/d41aca592a1e48f39e67edb9c47ea886
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Antiretroviral (ARV) drugs have improved prognoses for people living with HIV. However, HIV-associated neurocognitive disorders (HAND) persist despite undetectable viral loads. Some ARVs have been linked to neuropsychiatric effects that
Externí odkaz:
https://doaj.org/article/ef5043e73bc5412282fa621a3208e24d
Publikováno v:
Cells, Vol 13, Iss 17, p 1415 (2024)
Blood–brain barrier (BBB) injury and dysfunction following infection with the human immunodeficiency virus (HIV) enables viral entry into the brain, infection of resident brain cells, neuronal injury and subsequent neurodegeneration leading to HIV-
Externí odkaz:
https://doaj.org/article/548ceff0acc94cb5b00156848f5d3cee
Autor:
Yi Zhan, Dan-Chao Cai, Ying Liu, Fengxiang Song, Fei Shan, Pengrui Song, Guochao Chen, Yijun Zhang, He Wang, Yuxin Shi
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23342- (2024)
Background: Only few studies have focused on the metabolite differences between asymptomatic neurocognitive impairment (ANI) and cognitively normal people living with HIV (PLWH). The current study aims to examine whether brain metabolisms in basal ga
Externí odkaz:
https://doaj.org/article/54573ae91f664134bc6e09d6b3a70c72
Autor:
Catherine DeMarino, Maria Cowen, Anastasia Williams, Pooja Khatkar, Fardokht A. Abulwerdi, Lisa Henderson, Julia Denniss, Michelle L. Pleet, Delores R. Luttrell, Iosif Vaisman, Lance A. Liotta, Joseph Steiner, Stuart F. J. Le Grice, Avindra Nath, Fatah Kashanchi
Publikováno v:
Viruses, Vol 16, Iss 4, p 643 (2024)
Human immunodeficiency virus type 1 (HIV-1) infection can result in HIV-associated neurocognitive disorder (HAND), a spectrum of disorders characterized by neurological impairment and chronic inflammation. Combined antiretroviral therapy (cART) has e
Externí odkaz:
https://doaj.org/article/fa37b5ce3b4d4952af12868288bfeeab
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background HIV-associated neurocognitive disorder (HAND) negatively impacts quality of life (QoL) of people living with HIV who are on antiretroviral therapy (ART). Behavioural intervention adjunct to ART may improve QoL of people with HAND.
Externí odkaz:
https://doaj.org/article/fe02d9d11de54649873537cb1e7a87a2
Publikováno v:
Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-4 (2022)
Abstract Background Human immunodeficiency virus-1-associated neurocognitive disorder is a known complication in individuals treated with antiretroviral therapy. Cerebrospinal fluid escape, which is defined as discordant higher cerebrospinal fluid vi
Externí odkaz:
https://doaj.org/article/6aff2f5543dd4814818e231163ca1c9e