Identification of a novel first-generation HIV-1 circulating recombinant form (CRF152_DG) among people living with HIV in Karachi, Pakistan

Autor: Abdur Rashid, Li Kang, Feng Yi, Yimam Getaneh, Qingfei Chu, Sharaf Ali Shah, Syed Hani Abidi, Yiming Shao

Publikováno v: Microbiology Spectrum, Vol 12, Iss 7 (2024)

ABSTRACT The objective of this study was to characterize a novel circulating recombinant form of human immunodeficiency virus type 1 (HIV-1) among people living with HIV in Karachi, Pakistan. We conducted near-full-length genome (NFLG) sequencing on

Externí odkaz: https://doaj.org/article/2deb773971d94c1aa71263d9a8d09f3d

Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial

Autor: Sculier, Delphine, Wandeler, Gilles, Yerly Ferrillo, Sabine, Marinosci, Annalisa, Stoeckle, Marcel, Bernasconi, Enos, Braun, Dominique L., Vernazza, Pietro, Cavassini, Matthias, Buzzi, Marta, Metzner, Karin J., Decosterd, Laurent A., Günthard, Huldrych F., Schmid, Patrick, Limacher, Andreas, Egger, Matthias, Calmy, Alexandra, Swiss HIV Cohort Study (SHCS)

Publikováno v: PLoS Medicine
PLOS Medicine, Vol. 17, No 11 (2020) P. e1003421
PLoS Medicine, Vol 17, Iss 11, p e1003421 (2020)
PLoS medicine, vol. 17, no. 11, pp. e1003421
Sculier, Delphine; Wandeler, Gilles; Yerly, Sabine; Marinosci, Annalisa; Stoeckle, Marcel; Bernasconi, Enos; Braun, Dominique L; Vernazza, Pietro; Cavassini, Matthias; Buzzi, Marta; Metzner, Karin J; Decosterd, Laurent A; Günthard, Huldrych F; Schmid, Patrick; Limacher, Andreas; Egger, Matthias; Calmy, Alexandra (2020). Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial. PLoS medicine, 17(11), e1003421. Public Library of Science 10.1371/journal.pmed.1003421

Background Dolutegravir (DTG)–based dual therapy is becoming a new paradigm for both the initiation and maintenance of HIV treatment. The SIMPL’HIV study investigated the outcomes of virologically suppressed patients on standard combination antir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdd4c65511c7d667a0d2980ff73e398
https://pubmed.ncbi.nlm.nih.gov/33170863

New HIV-1 circulating recombinant form 94: from phylogenetic detection of a large transmission cluster to prevention in the age of geosocial-networking apps in France, 2013 to 2017

Autor: Ali Si-Mohammed, Jean-Dominique Poveda, Theresa Rabenja, B Visseaux, Karl Stefic, Fabienne De Oliveira, Anne Signori-Schmuck, Audrey Mirand, Magali Bouvier-Alias, Stéphanie Raymond, Vincent Calvez, Pantxika Bellecave, Coralie Pallier, Anne-Geneviève Marcelin, Véronique Schneider, Sidonie Lambert-Niclot, Chakib Alloui, Marie-Laure Chaix, Jean-Christophe Plantier, Diane Descamps, Elisabeth André-Garnier, Brice Malve, Marc Wirden

Publikováno v: Eurosurveillance
Eurosurveillance, 2019, 24 (39), ⟨10.2807/1560-7917.ES.2019.24.39.1800658⟩
Eurosurveillance, European Centre for Disease Prevention and Control, 2019, 24 (39), ⟨10.2807/1560-7917.ES.2019.24.39.1800658⟩

Background Ending the HIV pandemic must involve new tools to rapidly identify and control local outbreaks and prevent the emergence of recombinant strains with epidemiological advantages. Aim This observational study aimed to investigate in France a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0233a14ab344faf42353ccd877de8829
https://hal-normandie-univ.archives-ouvertes.fr/hal-02383043

Resistance to integrase inhibitors: a national study in HIV-1-infected treatment-naive and -experienced patients

Autor: Constance Delaugerre, Virginie Ferré, Anne Maillard, Vincent Calvez, Audrey Mirand, Anne-Geneviève Marcelin, Corinne Amiel, Julia Dina, Coralie Pallier, Hélène Le Guillou-Guillemette, Stéphanie Raymond, D. B. Fofana, Thomas Mourez, Hélène Jeulin, Samira Fafi-Kremer, Brigitte Montes, Pantxika Bellecave, Sophie Vallet, Thuy Van Nguyen, Diane Descamps, Catherine Roussel, Maxime Grude, Mary-Anne Trabaud, Charlotte Charpentier, Laurence Bocket, Philippe Flandre, Laura Le Guen, Anne Signori-Schmuck

Publikováno v: Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (5), pp.1368-1375. ⟨10.1093/jac/dkz021⟩
Journal of Antimicrobial Chemotherapy, 2019, 74 (5), pp.1368-1375. ⟨10.1093/jac/dkz021⟩

International audience; Objectives: To describe integrase strand transfer inhibitor (INSTI) resistance profiles and factors associated with resistance in antiretroviral-naive and -experienced patients failing an INSTI-based regimen in clinical practi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b81aa0dcf188502b617cb295d23cbb
https://hal-normandie-univ.archives-ouvertes.fr/hal-02154049

Once‐daily darunavir/ritonavir 400/100 mg in triple therapy: efficacy and penetration in seminal compartment in ANRS ‐165 DARULIGHT study

Autor: François Raffi, Jean-Michel Molina, Christine Katlama, Marie-Laure Chaix, Juliette Saillard, Minh Patrick Lê, Gilles Peytavin, Sylvie Chevret, Sebastien Gallien, Yazdan Yazdanpanah, Pierre Delobel

Publikováno v: British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, 2019, 85 (1), pp.277-280. ⟨10.1111/bcp.13796⟩

International audience; A key concern for reduced-dose antiretroviral regimens in maintenance strategies in HIV-infected patients is virological efficacy, as assessed by the suppression of HIV-RNA in blood and reservoirs, such as the genital tract. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d0799604e0f88f57976c2ef0ea70a0
https://ut3-toulouseinp.hal.science/hal-03639183