Zobrazeno 1 - 10
of 511
pro vyhledávání: '"HIV-1 DNA"'
Autor:
Aude Christelle Ka'e, Maria Mercedes Santoro, Leonardo Duca, Collins Ambe Chenwi, Ezechiel Ngoufack Jagni Semengue, Alex Durand Nka, Naomi-Karell Etame, Willy Leroi Togna Pabo, Grace Beloumou, Marie Laure Mpouel, Sandrine Djupsa, Desire Takou, Samuel Martin Sosso, Hyppolite K. Tchidjou, Vittorio Colizzi, Gregory-Edie Halle-Ekane, Carlo-Federico Perno, Sharon Lewin, R Brad Jones, Caroline T. Tiemessen, Francesca Ceccherini-Silberstein, Joseph Fokam
Publikováno v:
Journal of Virus Eradication, Vol 10, Iss 1, Pp 100367- (2024)
Background: With the advent of antiretroviral therapy (ART), most children living with HIV in sub-Saharan Africa (SSA) are growing toward adolescence, with scarcity of evidence on the size of viral reservoirs to enhance paediatric cure research strat
Externí odkaz:
https://doaj.org/article/3618feb39a9c4458986c039306a9b8f7
Autor:
Gilbert Mchantaf, Antoine Cheret, Adeline Melard, Asma Essat, Elise Gardiennet, Rebecca Bauer, Caroline Charre, Vincent Meiffredy, Lionel Piroth, Cécile Goujard, Laurence Meyer, Véronique Avettand-Fenoel
Publikováno v:
Journal of Virus Eradication, Vol 9, Iss 4, Pp 100357- (2023)
Background: Understanding factors affecting the size and the evolution of the HIV reservoir is essential for the development of curative strategies. This study aimed to assess the impact of antiretroviral therapy (ART) initiated during primary infect
Externí odkaz:
https://doaj.org/article/b1252e915fef4f8583db7a4cedaa010f
Akademický článek
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Autor:
Desmorys Raoul Moh, Jean-Baptiste Ntakpé, Delphine Gabillard, Arlette Ahoubet Yayo-Emieme, Anani Badjé, Gérard M. Kouame, Toni Thomas d’Aquin, Christine Danel, Xavier Anglaret, Serge P. Eholié
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background HIV-1 DNA persists in infected cells, forming viral reservoirs. Pre-antiretroviral treatment (ART) HIV-1 DNA load was reported to predict ART success in European severely immunocompromised patients. The aim of this study was to de
Externí odkaz:
https://doaj.org/article/98ff2c6d477e444695591a2e966d9aee
Autor:
Zhenhua Zhang, Wim Trypsteen, Marc Blaauw, Xiaojing Chu, Sofie Rutsaert, Linos Vandekerckhove, Wouter van der Heijden, Jéssica Cristina dos Santos, Cheng-Jian Xu, Morris A. Swertz, Andre van der Ven, Yang Li
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Combination antiretroviral treatment (cART) cannot eradicate HIV-1 from the body due to the establishment of persisting viral reservoirs which are not affected by therapy and reinitiate new rounds of HIV-1 replication after treatm
Externí odkaz:
https://doaj.org/article/9d335b9fadb540eeb1f023c64679c30e
Akademický článek
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Autor:
Johannes C. Botha, Matthew Byott, Moira J. Spyer, Paul R. Grant, Kathleen Gärtner, Wilson X. Chen, James Burton, Alasdair Bamford, Laura J. Waters, Carlo Giaquinto, Anna Turkova, Cindy L. Vavro, Eleni Nastouli
Publikováno v:
Viruses, Vol 15, Iss 9, p 1811 (2023)
Modern HIV-1 treatment effectively suppresses viral amplification in people living with HIV. However, the persistence of HIV-1 DNA as proviruses integrated into the human genome remains the main barrier to achieving a cure. Next-generation sequencing
Externí odkaz:
https://doaj.org/article/695f86d5c9f94204947163dc47d6a886
Autor:
Yongsong Yue, Yijia Li, Yizhi Cui, Nidan Wang, Yunda Huang, Wei Cao, Yang Han, Ting Zhu, Wei Lyu, Jing Xie, Xiaojing Song, Yanling Li, Tong Wang, Tuofu Zhu, Taisheng Li
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Factors predicting peripheral blood total HIV-1 DNA size in chronically infected patients with successfully suppressed viremia remain unclear. Prognostic power of such factors are of clinical significance for making clinical decis
Externí odkaz:
https://doaj.org/article/a13a77f642ad4edabeb786c8f4340c07
Akademický článek
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Autor:
Ling Lin, Yong-Song Yue, Ni-Dan Wang, Lei-Yan Wei, Yang Han, Xiao-Jing Song, Zhi-Feng Qiu, Wei Cao, Tai-Sheng Li
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-6 (2020)
Abstract Background A more time saving, convenient, reproducible, and scalable method is needed to assess total HIV-1 DNA levels. Methods Frozen whole blood and peripheral blood mononuclear cell (PBMC) samples both 200 μl at the same point were used
Externí odkaz:
https://doaj.org/article/d428099e57f34431bde6f2ddbcd37b93