Sexual transmission of an extensively drug-resistant HIV-1 strain

Autor: Guillaume Martin-Blondel, Jonathan Bigot, Pierre Delobel, Jacques Izopet, Marie Piffaut, Brigitte Montes, Kevin Bertrand, Stéphanie Raymond, Michelle Cazabat

Publikováno v: The Lancet HIV
The Lancet HIV, 2020, The Lancet HIV, 7 (8), pp.e521-e592. ⟨10.1016/S2352-3018(20)30205-8⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beea265329205c34b6194b5e13d040b2
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03156145

Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial

Autor: Sculier, Delphine, Wandeler, Gilles, Yerly Ferrillo, Sabine, Marinosci, Annalisa, Stoeckle, Marcel, Bernasconi, Enos, Braun, Dominique L., Vernazza, Pietro, Cavassini, Matthias, Buzzi, Marta, Metzner, Karin J., Decosterd, Laurent A., Günthard, Huldrych F., Schmid, Patrick, Limacher, Andreas, Egger, Matthias, Calmy, Alexandra, Swiss HIV Cohort Study (SHCS)

Publikováno v: PLoS Medicine
PLOS Medicine, Vol. 17, No 11 (2020) P. e1003421
PLoS Medicine, Vol 17, Iss 11, p e1003421 (2020)
PLoS medicine, vol. 17, no. 11, pp. e1003421
Sculier, Delphine; Wandeler, Gilles; Yerly, Sabine; Marinosci, Annalisa; Stoeckle, Marcel; Bernasconi, Enos; Braun, Dominique L; Vernazza, Pietro; Cavassini, Matthias; Buzzi, Marta; Metzner, Karin J; Decosterd, Laurent A; Günthard, Huldrych F; Schmid, Patrick; Limacher, Andreas; Egger, Matthias; Calmy, Alexandra (2020). Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial. PLoS medicine, 17(11), e1003421. Public Library of Science 10.1371/journal.pmed.1003421

Background Dolutegravir (DTG)–based dual therapy is becoming a new paradigm for both the initiation and maintenance of HIV treatment. The SIMPL’HIV study investigated the outcomes of virologically suppressed patients on standard combination antir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdd4c65511c7d667a0d2980ff73e398
https://pubmed.ncbi.nlm.nih.gov/33170863

Resistance to integrase inhibitors: a national study in HIV-1-infected treatment-naive and -experienced patients

Autor: Constance Delaugerre, Virginie Ferré, Anne Maillard, Vincent Calvez, Audrey Mirand, Anne-Geneviève Marcelin, Corinne Amiel, Julia Dina, Coralie Pallier, Hélène Le Guillou-Guillemette, Stéphanie Raymond, D. B. Fofana, Thomas Mourez, Hélène Jeulin, Samira Fafi-Kremer, Brigitte Montes, Pantxika Bellecave, Sophie Vallet, Thuy Van Nguyen, Diane Descamps, Catherine Roussel, Maxime Grude, Mary-Anne Trabaud, Charlotte Charpentier, Laurence Bocket, Philippe Flandre, Laura Le Guen, Anne Signori-Schmuck

Publikováno v: Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (5), pp.1368-1375. ⟨10.1093/jac/dkz021⟩
Journal of Antimicrobial Chemotherapy, 2019, 74 (5), pp.1368-1375. ⟨10.1093/jac/dkz021⟩

International audience; Objectives: To describe integrase strand transfer inhibitor (INSTI) resistance profiles and factors associated with resistance in antiretroviral-naive and -experienced patients failing an INSTI-based regimen in clinical practi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b81aa0dcf188502b617cb295d23cbb
https://hal-normandie-univ.archives-ouvertes.fr/hal-02154049

Trimeric heptad repeat synthetic peptides HR1 and HR2 efficiently inhibit HIV-1 entry

Autor: Mzoughi, Olfa, Teixido, Meritxell, Planès, Rémi, Serrero, Manutea, Hamimed, Ibtissem, Zurita, Esther, Moreno, Miguel, Granados, Giovana, Lakhdar-Ghazal, Faouzi, BenMohamed, Lbachir, Giralt, Ernest, Bahraoui, Elmostafa

Publikováno v: Bioscience Reports
Bioscience Reports, 2019, 39 (9), pp.1-15. ⟨10.1042/BSR20192196⟩
Bioscience reports, vol 39, iss 9

International audience; The trimeric heptad repeat domains HR1 and HR2 of the human immunodeficiency virus 1 (HIV-1) gp41 play a key role in HIV-1-entry by membrane fusion. To develop efficient inhibitors against this step, the corresponding trimeric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d6dfc3e3783a50d8ce5ed458ed29d60e
https://doi.org/10.1042/BSR20192196

Stable prevalence of transmitted drug resistance mutations and increased circulation of non-B subtypes in antiretroviral-naive chronically HIV-infected patients in 2015/2016 in France

Autor: Gilles Peytavin, Mary-Anne Trabaud, Anne Signori-Schmuck, Charlotte Charpentier, Marc Wirden, Cécile Henquell, Laurence Bocket, Catherine Delamare, Samira Fafi-Kremer, Jacques Izopet, Chakib Allaoui, Georges Dos Santos, A. Beby-Defaux, Benoit Visseaux, Virginie Ferré, Coralie Pallier, Diane Descamps, Stéphanie Marque-Juillet, Lambert Assoumou, Magali Bouvier-Alias, Sophie Vallet, Alexis de Rougemont, Hélène Le Guillou-Guillemette, Vincent Calvez, Stéphanie Raymond, Corinne Amiel, Honorine Fenaux, Anne De Monte, Francis Barin, Anne Krivine, Véronique Avettand-Fenoel, Annick Allardet-Servent, Jean-Christophe Plantier, Rachid Ait-Namane, Laurence Morand-Joubert, Marie-Laure Chaix, Camille Tumiotto, Maxime Grude, Anne Maillard, Laurence Courdavault, Brigitte Montes

Publikováno v: Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (5), pp.1417-1424. ⟨10.1093/jac/dkz011⟩
Journal of Antimicrobial Chemotherapy, 2019, 74 (5), pp.1417-1424. ⟨10.1093/jac/dkz011⟩

International audience; Objectives: We estimated the prevalence of transmitted-drug-resistance-associated mutations (TDRAMs) in antiretroviral-naive chronically HIV-1-infected patients.Patients and methods: TDRAMs were sought in samples from 660 diag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d3c4f5ee0320db9d5644b1b661f53d
https://pubmed.ncbi.nlm.nih.gov/30753724