Zobrazeno 1 - 10 of 31 pro vyhledávání: '"HIV antiretrovirals"'
1
Akademický článek
Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone
Autor: Shreya H. Dhume, Kayode Balogun, Ambalika Sarkar, Sebastian Acosta, Howard T. J. Mount, Lindsay S. Cahill, John G. Sled, Lena Serghides
Publikováno v: Frontiers in Molecular Neuroscience, Vol 17 (2024)
BackgroundCombination antiretroviral therapy (ART) use in pregnancy has been pivotal in improving maternal health and reducing perinatal HIV transmission. However, children born HIV-exposed uninfected fall behind their unexposed peers in several area
Externí odkaz: https://doaj.org/article/bce873f96d344bb199afb41b22cba351
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2
Akademický článek
A Pharmacokinetic Dose-Optimization Study of Cabotegravir and Bictegravir in a Mouse Pregnancy Model
Autor: Haneesha Mohan, Kieran Atkinson, Birgit Watson, Chanson J. Brumme, Lena Serghides
Publikováno v: Pharmaceutics, Vol 14, Iss 9, p 1761 (2022)
Animal pregnancy models can be useful tools to study HIV antiretroviral safety and toxicity and to perform mechanistic studies that are not easily performed in humans. Utilization of clinically relevant dosing in these models improves the relevance o
Externí odkaz: https://doaj.org/article/68d6932149ef422b859f477061bae2b5
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3
Akademický článek
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4
Akademický článek
Assessing the potential effects of nevirapine in South African surface water on fish growth: A chronic exposure of Oreochromis mossambicus
Autor: U. Marie Clémentine Nibamureke, Irene E.J. Barnhoorn, Gesina M. Wagenaar
Publikováno v: South African Journal of Science, Vol 115, Iss 3/4 (2019)
Aquatic environments around the world have become mixtures of different types of pollutants, including pharmaceuticals. The presence of pharmaceuticals in aquatic environments has raised concerns regarding the possibility of unintended effects on aqu
Externí odkaz: https://doaj.org/article/bd12c63e416f4f1d8f0aaa05e346f5b8
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5
Akademický článek
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6
Histopathological changes in Oreochromis mossambicus (Peters, 1852) ovaries after a chronic exposure to a mixture of the HIV drug nevirapine and the antibiotics sulfamethoxazole and trimethoprim
Autor: U. M. C. Nibamureke, G.M. Wagenaar
Publikováno v: Chemosphere
The burden of the human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) infection has transformed the African continent into a major consumer of antiretrovirals (ARVs) drugs. In addition to HIV burden, the African continent h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96841a84b2eb4d4c67d7e24eb266000f
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7
Nevirapine in African surface waters induces liver histopathology in Oreochromis mossambicus: A laboratory exposure study
Autor: G.M. Wagenaar, U. M. C. Nibamureke, I.E.J. Barnhoorn
Publikováno v: African Journal of Aquatic Science; Vol 44, No 1 (2019); 77–88
Nevirapine (NVP) is one of the HIV antiretrovirals detected recurrently in African surface waters. Liver side effects in humans were reported. Because the effects on fish are unknown, this study investigated the potential effects of NVP on selected b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a291f0d6d08bee77ad8a6d160bdf615d
https://doi.org/10.2989/16085914.2019.1571477
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8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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9
Assessing the potential effects of nevirapine in South African surface water on fish growth: A chronic exposure of Oreochromis mossambicus
Autor: G.M. Wagenaar, Marie Clémentine U. Nibamureke, I.E.J. Barnhoorn
Publikováno v: South African Journal of Science, Volume: 115, Issue: 3-4, Pages: 1-6, Published: APR 2019
South African Journal of Science, Vol 115, Iss 3/4 (2019)
Aquatic environments around the world have become mixtures of different types of pollutants, including pharmaceuticals. The presence of pharmaceuticals in aquatic environments has raised concerns regarding the possibility of unintended effects on aqu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c190954170d9c0e1d6a17ab74af49fa1
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0038-23532019000200006&lng=en&tlng=en
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10
Akademický článek
Stavudine dosage reduction: Effect on symptomatic hyperlactataemia and lactic acidosis in patients at Dr George Mukhari Hospital, Pretoria
Autor: M Nlooto, E Osuch, W du Plooy
Publikováno v: Southern African Journal of HIV Medicine, Vol 14, Iss 1, Pp 34-35 (2013)
A range of studies have demonstrated that symptomatic hyperlactataemia and lactic acidosis are associated with antiretroviral combinations containing stavudine. Following a meta-analysis showing that lower doses of stavudine are safer and as effectiv
Externí odkaz: https://doaj.org/article/a6581b47ce9d48eeb94753be04088f96
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