Zobrazeno 1 - 10
of 12
pro vyhledávání: '"HIV Protease/genetics"'
Autor:
Jens Verheyen, F Schöni-Affolter, Daniel Hoffmann, Vincent Aubert, Thomas Klimkait, Sabine Yerly, Jürg Böni, K Kletenkov, Daniel Struck
Publikováno v:
Journal of Antimicrobial Chemotherapy, Vol. 72, No 3 (2017) pp. 866-875
Background: HIV Gag mutations have been reported to confer PI drug resistance. However, clinical implications are still controversial and most current genotyping algorithms consider solely the protease gene for assessing PI resistance. Objectives: Ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af47a91554db3088ca2ab9849eebff57
https://archive-ouverte.unige.ch/unige:99804
https://archive-ouverte.unige.ch/unige:99804
Autor:
Anne Lavergne, Leila Adriouch, Félix Djossou, Myriam El Guedj, Mathieu Nacher, Vincent Lacoste, Alain Berlioz-Arthaud, Edith Darcissac, Pierre Couppié, Rachida Boukhari, Edouard Tanguy, Emmanuelle Papot, Vincent Vantilcke, Damien Donato, Jean-François Pouliquen
Publikováno v:
AIDS Research and Human Retroviruses
AIDS Research and Human Retroviruses, Mary Ann Liebert, 2016, 32 (8), pp.801-811. ⟨10.1089/aid.2016.0048⟩
AIDS Research and Human Retroviruses, Mary Ann Liebert, 2016, 32 (8), pp.801-811. ⟨10.1089/aid.2016.0048⟩
International audience; Little information is available on the molecular epidemiologic profile of HIV-1 in French Guiana, the French department with the highest HIV/AIDS incidence. To follow the evolution of HIV-1 diversity, we carried out a molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c3d49db146b0cdf439454ed11fc30d
https://hal-riip.archives-ouvertes.fr/pasteur-01583613
https://hal-riip.archives-ouvertes.fr/pasteur-01583613
Autor:
Nuriye Tasdelen Fisgin, Dilara Inan, Selda Sayin Kutlu, Atahan Cagatay, Fatma Sargin, Suda Tekin Koruk, Ilkay Karaoglan, Nurgul Ceran, Ayşe Inci, Murat Sayan, Volkan Korten, Bahadir Ceylan, Figen Kaptan, Aysel Kocagul Celikbas, Taner Yildirmak, Ayşe Willke, Halis Akalin, Kadriye Kart Yaşar, Dilek Yildiz Sevgi, Mustafa Kemal Çelen
HIV-1 replication is rapid and highly error-prone. Transmission of a drug-resistant HIV-1 strain is possible and occurs within the HIV-1-infected population. In this study, we aimed to determine the prevalence of transmitted drug resistance mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3beba6143c137de046d7f66cf93d79a1
Autor:
Alexandra U Scherrer, Bruno Ledergerber, Viktor von Wyl, Jürg Böni, Sabine Yerly, Thomas Klimkait, Cristina Cellerai, Hansjakob Furrer, Alexandra Calmy, Matthias Cavassini, Luigia Elzi, Pietro L Vernazza, Enos Bernasconi, Huldrych F Günthard, Swiss HIV Cohort Study
Publikováno v:
PLOS ONE, Vol. 7, No 6 (2012) P. e37983
PLoS ONE, Vol 7, Iss 6, p e37983 (2012)
PLoS ONE; Vol 7
PloS one
PLoS ONE
Scherrer, Alexandra U.; Ledergerber, Bruno; von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Cellerai, Cristina; Furrer, Hansjakob; Calmy, Alexandra; Cavassini, Matthias; Elzi, Luigia; Vernazza, Pietro L.; Bernasconi, Enos; Günthard, Huldrych F.; Swiss HIV Cohort Study, (2012). Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients. PLoS ONE, 7(6), e37983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0037983
Plos One, vol. 7, no. 6, pp. e37983
PLoS ONE, Vol 7, Iss 6, p e37983 (2012)
PLoS ONE; Vol 7
PloS one
PLoS ONE
Scherrer, Alexandra U.; Ledergerber, Bruno; von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Cellerai, Cristina; Furrer, Hansjakob; Calmy, Alexandra; Cavassini, Matthias; Elzi, Luigia; Vernazza, Pietro L.; Bernasconi, Enos; Günthard, Huldrych F.; Swiss HIV Cohort Study, (2012). Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients. PLoS ONE, 7(6), e37983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0037983
Plos One, vol. 7, no. 6, pp. e37983
Background Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naive patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7322ddc0fddb37cfc7322f0a1a05e5f5
https://doi.org/10.5167/uzh-67852
https://doi.org/10.5167/uzh-67852
Publikováno v:
Journal of Medical Virology, Vol. 81, No 4 (2009) pp. 573-7
Travel influences the spread of non-B subtypes of HIV in Europe. The aim of this study was to assess whether the spread of non-B subtypes occurred in Croatia, a country with a low level HIV infection. Phylogenetic analysis of the reverse transcriptas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729c8e7dbf745553d449648b179f71f4
https://pubmed.ncbi.nlm.nih.gov/19235840
https://pubmed.ncbi.nlm.nih.gov/19235840
Autor:
Anne Thérèse Vandenbroucke, Chris Verhofstede, Denis Pierard, Marie-Luce Delforge, Patrick Goubau, François Roman, Fedoua Echahidi, Katrien Fransen, Jean-Claude Schmit, Dolores Vaira, Kristel Van Laethem, Christine Lambert, J. Ruelle
Publikováno v:
BMC infectious diseases, 8
BMC Infectious Diseases
BMC Infectious Diseases, Vol 8, Iss 1, p 21 (2008)
Vrije Universiteit Brussel
BMC Infectious Diseases, Vol. 8, p. 21 (2008)
BMC INFECTIOUS DISEASES
BMC Infectious Diseases
BMC Infectious Diseases, Vol 8, Iss 1, p 21 (2008)
Vrije Universiteit Brussel
BMC Infectious Diseases, Vol. 8, p. 21 (2008)
BMC INFECTIOUS DISEASES
Guidelines established for the treatment of HIV-1 infection and genotype interpretation do not apply for HIV-2. Data about antiretroviral (ARV) drug efficacy and resistance mutations is scarce.
Journal Article
Research Support, Non-U.S. Gov
Journal Article
Research Support, Non-U.S. Gov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f2cb87440790a8413a680fb538f5ba
https://doi.org/10.1186/1471-2334-8-21
https://doi.org/10.1186/1471-2334-8-21
Autor:
Sasisopin Kiertiburanakul, Jintanat Ananworanich, Ploenchan Chetchotisakd, Phitsanu Raksakulkarn, Wisit Prasithsirikul, Sasiwimol Ubolyam, Bernard Hirschel, Somboon Tansuphasawadikul, Kiat Ruxrungtham, Warangkana Munsakul, Wendy Snowden, Malte Schutz, Sunee Sirivichayakul, Thidarat Jupimai
Publikováno v:
Antiviral therapy, 11(5), 631-635. International Medical Press Ltd
Antiviral Therapy, Vol. 11, No 5 (2006) pp. 631-635
Antiviral Therapy, Vol. 11, No 5 (2006) pp. 631-635
BackgroundThere are few data on the selection of resistance by ritonavir-boosted saquinavir (SQV/r), particularly in antiretroviral (ARV)-naive patients.ObjectiveTo assess the incidence of virological failure and evolution of resistance in ARV-naive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30001415b04b180aa5d6c23007966a5
https://pure.amc.nl/en/publications/absence-of-resistance-mutations-in-antiretroviralnaive-patients-treated-with-ritonavirboosted-saquinavir(937332ee-c397-4b29-b5b0-a014a2da870f).html
https://pure.amc.nl/en/publications/absence-of-resistance-mutations-in-antiretroviralnaive-patients-treated-with-ritonavirboosted-saquinavir(937332ee-c397-4b29-b5b0-a014a2da870f).html
Publikováno v:
Web of Science
Antiviral Therapy, Vol. 8, No 5 (2003) pp. 411-415
Antiviral Therapy, Vol. 8, No 5 (2003) pp. 411-415
Background We assessed whether treatment interruptions induce selection of mutations associated with drug resistance in the Swiss–Spanish Intermittent Treatment Trial (SSITT). Patients had been on HAART without previous failure and had undetectable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd39913d81a9250be2c39d8251a88e5c
https://pubmed.ncbi.nlm.nih.gov/14640388
https://pubmed.ncbi.nlm.nih.gov/14640388
Autor:
Arnaud Blondel, Técio G Benetti-Barbosa, Paulo R. Batista, Paulo Mascarello Bisch, Mauricio G. S. Costa, Nathan Desdouits, Pedro G. Pascutti
Publikováno v:
BMC Genomics
BMC Genomics, 2014, 15 (Suppl 7), pp.S5. ⟨10.1186/1471-2164-15-S7-S5⟩
BMC Genomics, BioMed Central, 2014, 15 (Suppl 7), pp.S5. ⟨10.1186/1471-2164-15-S7-S5⟩
BMC Genomics, 2014, 15 (Suppl 7), pp.S5. ⟨10.1186/1471-2164-15-S7-S5⟩
BMC Genomics, BioMed Central, 2014, 15 (Suppl 7), pp.S5. ⟨10.1186/1471-2164-15-S7-S5⟩
Background Over the last decades, a vast structural knowledge has been gathered on the HIV-1 protease (PR). Noticeably, most of the studies focused the B-subtype, which has the highest prevalence in developed countries. Accordingly, currently availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610234c729dfcb9ae24e0806a3632a13
http://europepmc.org/articles/PMC4243740
http://europepmc.org/articles/PMC4243740
Autor:
Manuel Battegay, J P Bru, Martin Rickenbach, J. P. Chave, Sabine Yerly, Luc Perrin, Amalio Telenti, P Rizzardi, Samir Vora, A L Veuthey, Bernard Hirschel, Markus Flepp, P. Vernazza
Publikováno v:
AIDS, Vol. 15, No 17 (2001) pp. 2287-2292
OBJECTIVE: To assess the impact of primary HIV infection (PHI) on the spread of HIV and the temporal trends in transmission of HIV drug resistance between 1996 and 1999 in Switzerland. METHODS: Sequencing of the genes for reverse transcriptase (RT) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997ed5f49df1837adbeb582e60a6f770
https://archive-ouverte.unige.ch/unige:7709
https://archive-ouverte.unige.ch/unige:7709