Zobrazeno 1 - 10 of 83 pro vyhledávání: '"HIV Infections / virology"'
1
Detection of antisense protein (ASP) RNA transcripts in individuals infected with human immunodeficiency virus type 1 (HIV-1)
Autor: Brian T. Foley, A. Mancarella, E. de Crignis, Giampietro Corradin, Tilmann Achsel, Giuseppe Pantaleo, Francesco A. Procopio, Claudia Bagni, Cecilia Graziosi
Publikováno v: Journal of General Virology, 100(5), 863-876. Microbiology Society
The Journal of general virology, vol. 100, no. 5, pp. 863-876
The detection of antisense RNA is hampered by reverse transcription (RT) non-specific priming, due to the ability of RNA secondary structures to prime RT in the absence of specific primers. The detection of antisense RNA by conventional RT-PCR does n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef64eb2637e0b1c67c64e47128777d4b
https://doi.org/10.1099/jgv.0.001244
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2
Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis
Autor: Armani-Tourret, Marie, Zhou, Zhicheng, Gasser, Romain, Staropoli, Isabelle, Cantaloube-Ferrieu, Vincent, Benureau, Yann, Garcia-Perez, Javier, Pérez-Olmeda, Mayte, Lorin, Valérie, Puissant-Lubrano, Bénédicte, Assoumou, Lambert, Delaugerre, Constance, Lelièvre, Jean-Daniel, Lévy, Yves, Mouquet, Hugo, Martin-Blondel, Guillaume, Alcami, Jose, Arenzana-Seisdedos, Fernando, Izopet, Jacques, Colin, Philippe, Lagane, Bernard
Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2021, 17 (4), pp.e1009526. ⟨10.1371/journal.ppat.1009526⟩
PLoS Pathogens, Vol 17, Iss 4, p e1009526 (2021)
PLoS Pathogens, 2021, 17 (4), pp.e1009526. ⟨10.1371/journal.ppat.1009526⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
HIV-1 infects CD4 T lymphocytes (CD4TL) through binding the chemokine receptors CCR5 or CXCR4. CXCR4-using viruses are considered more pathogenic, linked to accelerated depletion of CD4TL and progression to AIDS. However, counterexamples to this para
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::81b742e2a985b3fcdc056844ca0386d7
https://hal.sorbonne-universite.fr/hal-03204143/document
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3
Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART
Autor: Laura N Walti, Susana Posada Céspedes, Enos Bernasconi, Pietro Vernazza, Chenjie Wan, Matthieu Perreau, Huldrych F. Günthard, François Blanquart, Nadine Bachmann, Sabine Yerly, Teja Turk, Jacques Fellay, Volker Roth, Thomas Klimkait, Manuel Battegay, Jasmina Bogojeska, Niko Beerenwinkel, Venelin Mitov, Karin J. Metzner, Kathrin Neumann, Matthias Cavassini, Jürg Böni, Alexandra Calmy, Roger D. Kouyos
Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-19198-7⟩
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications, Vol. 11, No 1 (2020) P. 5542
Nature communications, vol. 11, no. 1, pp. 5542
Wan, Chenjie; Bachmann, Nadine; Mitov, Venelin; Blanquart, François; Céspedes, Susana Posada; Turk, Teja; Neumann, Kathrin; Beerenwinkel, Niko; Bogojeska, Jasmina; Fellay, Jacques; Roth, Volker; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Battegay, Manuel; Walti, Laura; Calmy, Alexandra; Vernazza, Pietro; Bernasconi, Enos; ... (2020). Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART. Nature communications, 11(1), p. 5542. Nature Publishing Group 10.1038/s41467-020-19198-7
The HIV-1 reservoir is the major hurdle to curing HIV-1. However, the impact of the viral genome on the HIV-1 reservoir, i.e. its heritability, remains unknown. We investigate the heritability of the HIV-1 reservoir size and its long-term decay by an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b95dcfa260f3545209002c69a89fff3
https://hal.archives-ouvertes.fr/hal-03066281/document
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4
HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection
Autor: Enos Bernasconi, Cyril Shah, Pietro Vernazza, Andri Rauch, Dominique L Braun, Jürg Böni, Luisa Salazar-Vizcaya, Sabine Yerly, Huldrych F. Günthard, Roger D. Kouyos, Jan Fehr, Aude Nguyen, Marcel Stoeckle, Teja Turk, Herbert A Mbunkah, Michael Huber, Matthias Cavassini, Karin J. Metzner, Louisa A Carlisle
Publikováno v: Viruses, vol. 12, no. 11, pp. E1241
Viruses, Vol. 12, No 11 (2020) P. 1241
Viruses
Volume 12
Issue 11
Carlisle, Louisa A; Turk, Teja; Metzner, Karin J; Mbunkah, Herbert A; Shah, Cyril; Böni, Jürg; Huber, Michael; Braun, Dominique L; Fehr, Jan; Salazar-Vizcaya, Luisa; Rauch, Andri; Yerly, Sabine; Nguyen, Aude; Cavassini, Matthias; Stoeckle, Marcel; Vernazza, Pietro; Bernasconi, Enos; Günthard, Huldrych F; Kouyos, Roger D (2020). HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection. Viruses, 12(11) Molecular Diversity Preservation International MDPI 10.3390/v12111241
Viruses, Vol 12, Iss 1241, p 1241 (2020)
HIV-1 genetic diversity can be used to infer time since infection (TSI) and infection recency. We adapted this approach for HCV and identified genomic regions with informative diversity. We included 72 HCV/HIV-1 coinfected participants of the Swiss H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb46f82db2a2ede9082d5e551bf4a903
https://serval.unil.ch/resource/serval:BIB_D73F11FC1FB6.P001/REF.pdf
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6
Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals
Autor: Guillaume Martin-Blondel, Jacques Izopet, Mary Requena, Bertrand Suc, Laurent Alric, Manon Nayrac, Nicolas Carrere, Pierre Delobel, Karl Barange, Claire Loiseau, Michelle Cazabat
Publikováno v: Mucosal Immunology
Mucosal Immunology, 2020, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
International audience; Gut CD4+ T cells are incompletely restored in most HIV-1-infected individuals on antiretroviral therapy, notably Th17 cells, a key subset in mucosal homeostasis. By contrast, gut Th22 cells are usually restored at normal frequ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7063cc54ac3d26c97d0c23435a80444c
https://ut3-toulouseinp.hal.science/hal-03157449
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7
HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation
Autor: Mary Carrington, Tobias L. Lenz, Federica Pierini, Jacques Fellay, Paul J. McLaren, Jatin Arora
Publikováno v: Molecular biology and evolution, vol. 37, no. 3, pp. 639-650
Molecular Biology and Evolution
Pathogen-mediated balancing selection is regarded as a key driver of host immunogenetic diversity. A hallmark for balancing selection in humans is the heterozygote advantage at genes of the human leukocyte antigen (HLA), resulting in improved HIV-1 c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996687938bd13cc63fdb99d363b53a5f
https://serval.unil.ch/resource/serval:BIB_4A4E20C0A676.P001/REF.pdf
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8
HIV-1 Vpr mediates the depletion of the cellular repressor CTIP2 to counteract viral gene silencing
Autor: Forouzanfar, F., Ali, S., Wallet, C., De Rovere, M., Ducloy, C., El Mekdad, H., El Maassarani, M., Aït-Ammar, A., Van Assche, J., Boutant, E., Daouad, F., Margottin-Goguet, F., Moog, C., Van Lint, C., Schwartz, C., Rohr, O.
Publikováno v: Scientific reports, 9 (1
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-48689-x⟩
Mammals have evolved many antiviral factors impacting different steps of the viral life cycle. Associated with chromatin-modifying enzymes, the cellular cofactor CTIP2 contributes to HIV-1 gene silencing in latently infected reservoirs that constitut
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8dc4e9eb948bcfbf0e2442fbd58e3f2f
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/296885
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9
New HIV-1 circulating recombinant form 94: from phylogenetic detection of a large transmission cluster to prevention in the age of geosocial-networking apps in France, 2013 to 2017
Autor: Ali Si-Mohammed, Jean-Dominique Poveda, Theresa Rabenja, B Visseaux, Karl Stefic, Fabienne De Oliveira, Anne Signori-Schmuck, Audrey Mirand, Magali Bouvier-Alias, Stéphanie Raymond, Vincent Calvez, Pantxika Bellecave, Coralie Pallier, Anne-Geneviève Marcelin, Véronique Schneider, Sidonie Lambert-Niclot, Chakib Alloui, Marie-Laure Chaix, Jean-Christophe Plantier, Diane Descamps, Elisabeth André-Garnier, Brice Malve, Marc Wirden
Publikováno v: Eurosurveillance
Eurosurveillance, 2019, 24 (39), ⟨10.2807/1560-7917.ES.2019.24.39.1800658⟩
Eurosurveillance, European Centre for Disease Prevention and Control, 2019, 24 (39), ⟨10.2807/1560-7917.ES.2019.24.39.1800658⟩
Background Ending the HIV pandemic must involve new tools to rapidly identify and control local outbreaks and prevent the emergence of recombinant strains with epidemiological advantages. Aim This observational study aimed to investigate in France a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0233a14ab344faf42353ccd877de8829
https://hal-normandie-univ.archives-ouvertes.fr/hal-02383043
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10
Performance evaluation of the Vela Dx Sentosa next-generation sequencing system for HIV-1 DNA genotypic resistance
Autor: Pierre Delobel, Caroline Lefebvre, Stéphanie Raymond, Jacques Izopet, Florence Nicot, Luce Minier, Guillaume Martin-Blondel, Romain Carcenac, Florence Abravanel, Agnès Harter
Publikováno v: Journal of Clinical Virology
Journal of Clinical Virology, Elsevier, 2020, 122, pp.104229-104233. ⟨10.1016/j.jcv.2019.104229⟩
Journal of Clinical Virology, 2020, 122, pp.104229. ⟨10.1016/j.jcv.2019.104229⟩
International audience; Background: Patients on antiretroviral therapy could benefit from HIV-1 DNA resistance genotyping for exploring virological failure with low viral load or to guide treatment simplification. Few new generation sequencing data a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8d87573370c8f71dd0b86b647b317a
https://pubmed.ncbi.nlm.nih.gov/31809945
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