Zobrazeno 1 - 2
of 2
pro vyhledávání: '"HIV Infections/ drug therapy/immunology/transmission"'
Publikováno v:
Journal of Investigative Dermatology, Vol. 127, No 6 (2007) pp. 1436-43
Development of topical microbicides that prevent sexual transmission of HIV is an active area of investigation. The purpose of this study was to test the ability of the potent membrane fusion inhibitor C34, an HIV gp41 antagonist, to block HIV infect
Autor:
Ploenchan Chetchotisakd, Reto Nüesch, Claudette S. Satchell, David A. Cooper, Warangkana Munsakul, Kiat Ruxrungtham, Michelle Le Braz, Enos Bernasconi, Daniel Genné, Jintanat Ananworanich, Phitsanu Raksakulkarn, Sabine Yerly, Praphan Phanuphak, Urs Karrer, Matthias Cavassini, Dominic Leduc, Sunee Sirivichayakul, Andrew Hill, Wisit Prasithsirikul, Angèle Gayet-Ageron, Bernard Hirschel, Hansjakob Furrer, Sasisopin Kiertiburanakul, Thomas V. Perneger, Somboon Tansuphasawasdikul, Luc Perrin, Pietro Vernazza
Publikováno v:
The Lancet, Vol. 368, No 9534 (2006) pp. 459-465
Lancet, 368(9534), 459-465. Elsevier Limited
Lancet, 368(9534), 459-465. Elsevier Limited
BACKGROUND: Stopping antiretroviral therapy in patients with HIV-1 infection can reduce costs and side-effects, but carries the risk of increased immune suppression and emergence of resistance. METHODS: 430 patients with CD4-positive T-lymphocyte (CD