HIV Skews a Balanced Mtb-Specific Th17 Response in Latent Tuberculosis Subjects to a Pro-inflammatory Profile Independent of Viral Load:HIV alters the nature of the Mtb-specific Th17 response

Autor: Rakshit, Srabanti, Hingankar, Nitin, Alampalli, Shuba Varshini, Adiga, Vasista, Sundararaj, Bharath K., Sahoo, Pravat Nalini, Finak, Greg, Uday Kumar J, Anto Jesuraj, Dhar, Chirag, D'Souza, George, Virkar, Rashmi Govind, Ghate, Manisha, Thakar, Madhuri R., Paranjape, Ramesh S., De Rosa, Stephen C., Ottenhoff, Tom H.M., Vyakarnam, Annapurna

Publikováno v: Rakshit, S, Hingankar, N, Alampalli, S V, Adiga, V, Sundararaj, B K, Sahoo, P N, Finak, G, Uday Kumar J, A J, Dhar, C, D'Souza, G, Virkar, R G, Ghate, M, Thakar, M R, Paranjape, R S, De Rosa, S C, Ottenhoff, T H M & Vyakarnam, A 2020, ' HIV Skews a Balanced Mtb-Specific Th17 Response in Latent Tuberculosis Subjects to a Pro-inflammatory Profile Independent of Viral Load : HIV alters the nature of the Mtb-specific Th17 response ', Cell Reports, vol. 33, no. 9, 108451 . https://doi.org/10.1016/j.celrep.2020.108451

This study provides insight on how HIV may drive tuberculosis (TB). Rakshit et al. demonstrate that HIV infection of latent TB subjects profoundly alters specific immune subsets implicated in anti-TB immunity, which is independent of cellular viral b

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https://kclpure.kcl.ac.uk/en/publications/ee8128ea-f8eb-4168-932a-61c84628d1e8

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