Zobrazeno 1 - 10
of 56
pro vyhledávání: '"HITOSHI KOJO"'
Autor:
Hitoshi Kojo, Masao Fukagawa, Kaoru Tajima, Akiko Suzuki, Takao Fujimura, Ichiro Aramori, Ken-ichi Hayashi, Shintaro Nishimura
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 3, Pp 347-355 (2003)
ABSTRACT: The nuclear receptor PPAR (peroxisome proliferator-activated receptor) has three subtypes named α, δ(β), and γ that may act as receptors for a range of compounds including antihyperglycaemic drugs, insulin sensitizers, and non-steroidal
Externí odkaz:
https://doaj.org/article/143313b742014705beb6f954d5c8a6c8
Publikováno v:
Chem-Bio Informatics Journal. 16:13-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da0c5b5d26f57aa0cdcdf32806590fce
https://doi.org/10.1273/cbij.16.13
https://doi.org/10.1273/cbij.16.13
Autor:
Kiyoshi Aita, Dobun Hayashi, Hideyuki Koide, Kenichi Sato, Hitoshi Kojo, Tsugumi Okuzawa, Tetsuro Nakamura, Wakako Suhara, Satoru Nakano
Publikováno v:
Journal of Food Biochemistry. 35:776-791
A saponin-enriched soybean extract was tested for agonistic activities against a series of nuclear receptors including peroxisome proliferator-activated receptors (PPARs) and cholesterol metabolism-related, retinoid-related, hormone-related and detox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b5e433d6f227a9fa2e0bd0e8a6614d
https://doi.org/10.1111/j.1745-4514.2010.00416.x
https://doi.org/10.1111/j.1745-4514.2010.00416.x
Publikováno v:
Biochemical Pharmacology. 71:1184-1197
Adipocyte dysfunction is strongly associated with the development of obesity and insulin resistance. It is accepted that the regulation of adipocytokine secretion or the adipocyte specific gene expression is one of the most important targets for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d7bb7e25d475b8247adc063c222db9
https://doi.org/10.1016/j.bcp.2005.12.042
https://doi.org/10.1016/j.bcp.2005.12.042
Autor:
Shigeki Satoh, Hiroe Sawai, Hitoshi Kojo, Noriyuki Morikawa, Teruo Oku, Yoshitada Notsu, Tsuyoshi Mizutani, Noriaki Inamura, Ichiro Aramori, Yuki Sawada, Chie Hatori, Yoshito Abe, Hiroshi Kayakiri, Takayuki Inoue, Masayuki Asano, Junko Zenkoh, Kunio Nakahara
Publikováno v:
Molecular Pharmacology. 52:16-20
Kinins, members of a family of peptides released from kininogens by the action of kallikreins, exhibit a variety of biological activities including vasodilation, increased vascular permeability, contraction of smooth muscle cells, and activation of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7744af6d1d431b32ecbd75a2f1182eb6
https://doi.org/10.1124/mol.52.1.16
https://doi.org/10.1124/mol.52.1.16
Autor:
Yoshitada Notsu, Jiro Hirosumi, Satoru Takahashi, Osamu Nakayama, Kozo Sawada, Hitoshi Kojo, Noboru Chida
Publikováno v:
The Prostate. 31:241-249
BACKGROUND Steroid 5α-reductase is implicated in the pathogenesis of benign prostatic hyperplasia (BPH). We studied the in vitro and in vivo effects of FR146687, a new inhibitor of 5α-reductase. METHODS Two isozymes of rat and human 5α-reductases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46c1b98d587669a74648d2c776bf8890
https://doi.org/10.1002/(sici)1097-0045(19970601)31:4<241::aid-pros5>3.0.co
https://doi.org/10.1002/(sici)1097-0045(19970601)31:4<241::aid-pros5>3.0.co
Autor:
Hitoshi Kojo, Junko Zenkoh, Ichiro Aramori, Morita Iwami, Kozo Nakamura, Masayuki Asano, Noriyuki Morikawa, Nuala O’Donnell, Yoshitada Notsu
Publikováno v:
Molecular Pharmacology. 51:171-176
We describe the receptor binding and antagonistic properties of two novel nonpeptide antagonists, FR167344 (3-bromo-8-[2,6-dichloro-3-[ N -[( E )-4-( N , N -dimethylcarbamoyl)cinnamidoacetyl]- N -methylamino]benzyloxy]-2-methylimidazo[1,2-a]pyridine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0390722fac76a6658d2a118792aab7f4
https://doi.org/10.1124/mol.51.2.171
https://doi.org/10.1124/mol.51.2.171
Publikováno v:
PAIN RESEARCH. 12:131-137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1218026dba7ee1c5f4576851ef215f50
https://doi.org/10.11154/pain.12.131
https://doi.org/10.11154/pain.12.131
Publikováno v:
PAIN RESEARCH. 12:15-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c61307ad37b56f17b43570de73a6a2d3
https://doi.org/10.11154/pain.12.15
https://doi.org/10.11154/pain.12.15
Autor:
M. Okuhara, O. Nakayama, M. Inami, Y. Notsu, S. Takahashi, K. Sawada, Hitoshi Kojo, J. Hirosumi, T. Fagan, N. Chida
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 52:357-363
Steroid 5 alpha-reductase is an enzyme which converts testosterone into 5 alpha-dihydrotestosterone (DHT) and is implicated in the pathogenesis of benign prostatic hyperplasia (BPH) in men. We studied in vitro effects of FK143, a nonsteroidal new com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa6e2081103fe0237119632e0e9a022
https://doi.org/10.1016/0960-0760(94)00187-q
https://doi.org/10.1016/0960-0760(94)00187-q