Zobrazeno 1 - 10
of 43
pro vyhledávání: '"HITOMI AJIMIZU"'
Autor:
Kazutaka Hosoya, Hiroaki Ozasa, Masahiro Tanji, Hiroshi Yoshida, Hitomi Ajimizu, Takahiro Tsuji, Hironori Yoshida, Yukinori Terada, Noritaka Sano, Yohei Mineharu, Susumu Miyamoto, Toyohiro Hirai, Yoshiki Arakawa
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Brain metastasis (BrM) is prevalent among patients with NSCLC, and surgical resection of BrM constitutes a promising treatment strategy for local management and histopathological diagnosis, although it is offered for a select grou
Externí odkaz:
https://doaj.org/article/f3bf40f9ddff4063840a65ebc9bc60ca
Autor:
Hiroshi Yoshida, Hiroaki Ozasa, Kentaro Hashimoto, Yusuke Shima, Keiichiro Suminaga, Hitomi Ajimizu, Takashi Nomizo, Hironori Yoshida, Masahiro Yoshioka, Masashi Kanai, Takehito Shukuya, Manabu Muto, Toyohiro Hirai
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 14, Iss , Pp 100286- (2024)
Among cases of non-small cell lung cancer (NSCLC) with EGFR mutations, NSCLC with deletions in EGFR exon 19 or 21 L858R account for 85 %. Frequency of NSCLC with minor mutations in EGFR is about 9 %, whilst EGFR exon 20 insertion mutation account for
Externí odkaz:
https://doaj.org/article/9c163bc24b6e4a9181dc97cc3c256896
Autor:
Yusuke Kataoka, Naoya Tanabe, Masahiro Shirata, Nobuyoshi Hamao, Issei Oi, Tomoki Maetani, Yusuke Shiraishi, Kentaro Hashimoto, Masatoshi Yamazoe, Hiroshi Shima, Hitomi Ajimizu, Tsuyoshi Oguma, Masahito Emura, Kazuo Endo, Yoshinori Hasegawa, Tadashi Mio, Tetsuhiro Shiota, Hiroaki Yasui, Hitoshi Nakaji, Michiko Tsuchiya, Keisuke Tomii, Toyohiro Hirai, Isao Ito
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background The substantial heterogeneity of clinical presentations in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia still requires robust chest computed tomography analysis to identify high-risk patient
Externí odkaz:
https://doaj.org/article/dcd0d6febee64d4f9c3eff8fa47c24fd
Autor:
Hitomi Ajimizu, Hiroaki Ozasa, Susumu Sato, Tomoko Funazo, Yuichi Sakamori, Takashi Nomizo, Kiyomitsu Kuninaga, Tatsuya Ogimoto, Kazutaka Hosoya, Masatoshi Yamazoe, Takahiro Tsuji, Hironori Yoshida, Ryo Itotani, Kentaro Ueno, Young Hak Kim, Shigeo Muro, Toyohiro Hirai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) may coexist with lung cancer, but the impact on prognosis is uncertain. Moreover, it is unclear whether pharmacological treatment for COPD improves the patient’s prognosis. We retrospectively in
Externí odkaz:
https://doaj.org/article/f3c791af74a046499c35180097eeba07
Autor:
Hitomi Ajimizu, Hiroaki Ozasa, Susumu Sato, Tomoko Funazo, Yuichi Sakamori, Takashi Nomizo, Kiyomitsu Kuninaga, Tatsuya Ogimoto, Kazutaka Hosoya, Masatoshi Yamazoe, Takahiro Tsuji, Hironori Yoshida, Ryo Itotani, Kentaro Ueno, Young Hak Kim, Shigeo Muro, Toyohiro Hirai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/54a067459b054ee180ce6a077620ee5a
Autor:
Takahiro Tsuji, Hiroaki Ozasa, Wataru Aoki, Shunsuke Aburaya, Tomoko Yamamoto Funazo, Koh Furugaki, Yasushi Yoshimura, Masatoshi Yamazoe, Hitomi Ajimizu, Yuto Yasuda, Takashi Nomizo, Hironori Yoshida, Yuichi Sakamori, Hiroaki Wake, Mitsuyoshi Ueda, Young Hak Kim, Toyohiro Hirai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Relapse is a limitation for the efficacy of the anaplastic lymphoma kinase (ALK)-inhibitor alectinib in ALK-rearranged lung cancer. Here, the authors show that YAP1 activation upon alectinib treatment leads to therapy resistance and that inhibiting b
Externí odkaz:
https://doaj.org/article/3f80ddddea7640be87705e31f5e46a2a
Autor:
Takahiro Tsuji, Young Hak Kim, Hiroaki Ozasa, Yuichi Sakamori, Hiroki Nagai, Hitomi Ajimizu, Yoshitaka Yagi, Atsuyuki Furukawa, Hironori Haga, Michiaki Mishima
Publikováno v:
Respiratory Medicine Case Reports, Vol 15, Iss C, Pp 48-50 (2015)
Introduction: Pulmonary spindle cell carcinoma (SpCC) is a rare subtype of non-small-cell lung cancer (NSCLC) and, in general, is chemoresistance. Case: A sixty-five year-old male patient with metastatic pulmonary SpCC was initially treated with cisp
Externí odkaz:
https://doaj.org/article/072e36e2b7f54ce7a275f59bb9829aa0
Autor:
Young Hak Kim, Toyohiro Hirai, Mitsuyoshi Ueda, Yuichi Sakamori, Hiroki Nagai, Yoshitaka Yagi, Hironori Yoshida, Koichi Hasegawa, Kiyoshi Uemasu, Takashi Nomizo, Yuto Yasuda, Ryoko Okutani, Hitomi Ajimizu, Yasushi Yoshimura, Koh Furugaki, Tomoko Funazo, Shunsuke Aburaya, Wataru Aoki, Hiroaki Ozasa, Takahiro Tsuji
Fig. S1. Supplementary data for Fig. 1 Fig. S2. Supplementary drug sensitivity data to ALK inhibitors in KTOR1 and KTOR1-RE. Fig. S3. Supplementary results of the phosphoproteome analysis Fig. S4. Saracatinib sensitized KTOR1-RE cells to crizotinib F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f8b92c4e090d208d1fd9cf32555131
https://doi.org/10.1158/1541-7786.22515762
https://doi.org/10.1158/1541-7786.22515762
Autor:
Young Hak Kim, Toyohiro Hirai, Mitsuyoshi Ueda, Yuichi Sakamori, Hiroki Nagai, Yoshitaka Yagi, Hironori Yoshida, Koichi Hasegawa, Kiyoshi Uemasu, Takashi Nomizo, Yuto Yasuda, Ryoko Okutani, Hitomi Ajimizu, Yasushi Yoshimura, Koh Furugaki, Tomoko Funazo, Shunsuke Aburaya, Wataru Aoki, Hiroaki Ozasa, Takahiro Tsuji
Supplementary Figure S1-S6 and Table S1-S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5281c8717743da816c7fd5fb10b85788
https://doi.org/10.1158/1541-7786.22515759
https://doi.org/10.1158/1541-7786.22515759
Autor:
Toyohiro Hirai, Young Hak Kim, Hironori Yoshida, Yuichi Sakamori, Takashi Nomizo, Yuto Yasuda, Hitomi Ajimizu, Tetsuya Oguri, Yasushi Yoshimura, Koh Furugaki, Hiroaki Ozasa, Takahiro Tsuji, Tomoko Funazo
Alectinib is used as a first-line treatment for anaplastic lymphoma kinase (ALK)-rearranged non–small cell lung cancer (NSCLC). Whereas other ALK inhibitors have been reported to be involved in resistance to ATP-binding cassette (ABC) transporters,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7a854b2d31d7a986a69421d9175fec
https://doi.org/10.1158/1535-7163.c.6542827
https://doi.org/10.1158/1535-7163.c.6542827