Zobrazeno 1 - 10
of 1 823
pro vyhledávání: '"HISTAMINE H4 RECEPTOR"'
Autor:
Jung Won Kwon, Kihwang Lee, Sang Wha Kim, Jisu Park, Jung Joo Hong, Jeong-Hwan Che, Seung Hyeok Seok
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Diabetic retinopathy (DR) is a prevalent complication of diabetes, often resulting in vision loss and blindness. Existing treatments primarily aim to control blood sugar levels and inhibit angiogenesis. However, current therapies for DR, suc
Externí odkaz:
https://doaj.org/article/e057b41357284768b4a61dddc1045013
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Abdulaziz M. S. Alsaad, Mushtaq A. Ansari, Ahmed Nadeem, Sabry M. Attia, Saleh A. Bakheet, Hatun A. Alomar, Sheikh F. Ahmad
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12991 (2023)
We sought to assess the impact of 4-Methylhistamine (4-MeH), a specific agonist targeting the Histamine H4 Receptor (H4R), on the progression of experimental autoimmune encephalomyelitis (EAE) and gain insight into the underlying mechanism. EAE is a
Externí odkaz:
https://doaj.org/article/aaa6c3ddcfc44388af99f5b50c5d67c6
Autor:
Agnieszka Olejarz-Maciej, Szczepan Mogilski, Tadeusz Karcz, Tobias Werner, Katarzyna Kamińska, Jarosław Kupczyk, Ewelina Honkisz-Orzechowska, Gniewomir Latacz, Holger Stark, Katarzyna Kieć-Kononowicz, Dorota Łażewska
Publikováno v:
Molecules, Vol 28, Iss 10, p 4199 (2023)
Pain is a very unpleasant experience that makes life extremely uncomfortable. The histamine H4 receptor (H4R) is a promising target for the treatment of inflammatory and immune diseases, as well as pain. H4R ligands have demonstrated analgesic effect
Externí odkaz:
https://doaj.org/article/a1345330633546a088998c7589f4d043
Autor:
Jun Shoji
Publikováno v:
Allergology International, Vol 69, Iss 4, Pp 496-504 (2020)
Allergic conjunctival diseases (ACDs) are inflammatory diseases of the conjunctiva and cornea caused predominantly by the IgE-mediated immediate hypersensitivity response. Allergic conjunctival diseases include allergic conjunctivitis, vernal keratoc
Externí odkaz:
https://doaj.org/article/18a4f0ec32fd4396b08126d29b3510a4
Autor:
Hua Peng, Jian Wang, Xiao Yan Ye, Jie Cheng, Cheng Zhi Huang, Li Yue Li, Tian Ying Li, Chun Wei Li
Publikováno v:
Clinical and Translational Allergy, Vol 9, Iss 1, Pp 1-4 (2019)
Abstract Histamine H1 receptor (H1R) and histamine H4 receptor (H4R) are essential in allergic inflammation. The roles of H4R have been characterized in T cell subsets, whereas the functional properties of H4R in monocytes remain unclear. In the curr
Externí odkaz:
https://doaj.org/article/1e5be6328c8345c1874e5af931ac9c15
Autor:
Abdelhakim Salem, Tuula Salo
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/40d116a28cb54b56bd75138368a4fbe3
Autor:
Nhung Quynh Do, Shengdao Zheng, Sarang Oh, Quynh T. N. Nguyen, Minzhe Fang, Minseon Kim, Junhui Choi, Myeong-Ju Kim, Jeehaeng Jeong, Tae-Hoo Yi
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 104 (2021)
Although Myrciaria dubia (camu-camu) has been shown to exert anti-oxidant and anti-inflammatory effects in both in vitro and in vivo studies, its use in allergic responses has not been elucidated. In the present study, the anti-allergic effect of 70%
Externí odkaz:
https://doaj.org/article/3065739b56a94b6e8025412b657fd778
Autor:
Carina Höring, Marcus Conrad, Christian A. Söldner, Jinan Wang, Heinrich Sticht, Andrea Strasser, Yinglong Miao
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10047 (2021)
G protein-coupled receptors (GPCRs) are targets of extracellular stimuli and hence occupy a key position in drug discovery. By specific and not yet fully elucidated coupling profiles with α subunits of distinct G protein families, they regulate cell
Externí odkaz:
https://doaj.org/article/3fd1b6a9f3614a8d849c8510ffe9c43e