Zobrazeno 1 - 10
of 299
pro vyhledávání: '"HISASHI UHARA"'
Autor:
Yuji Kan, Hisashi Uhara
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/c8b3f32781b54b8c9563f23697e802c2
Autor:
Tokimasa Hida, Masashi Idogawa, Junji Kato, Yukiko Kiniwa, Kohei Horimoto, Sayuri Sato, Masahide Sawada, Shoichiro Tange, Masae Okura, Ryuhei Okuyama, Takashi Tokino, Hisashi Uhara
Publikováno v:
Cancer Medicine, Vol 13, Iss 22, Pp n/a-n/a (2024)
ABSTRACT Background Acral and mucosal melanomas are more prevalent in Asians than in Caucasians, unlike cutaneous melanomas, which are predominant in Caucasians. Recent studies have suggested that non‐Caucasian cutaneous melanomas responded less to
Externí odkaz:
https://doaj.org/article/652c93914c344ec983391bfbd33d763b
Autor:
Hiroshi Ohguro, Megumi Watanabe, Tatsuya Sato, Nami Nishikiori, Araya Umetsu, Megumi Higashide, Toshiyuki Yano, Hiromu Suzuki, Akihiro Miyazaki, Kohichi Takada, Hisashi Uhara, Masato Furuhashi, Fumihito Hikage
Publikováno v:
Cells, Vol 13, Iss 18, p 1549 (2024)
Cell culture methods are indispensable strategies for studies in biological sciences and for drug discovery and testing. Most cell cultures have been developed using two-dimensional (2D) culture methods, but three-dimensional (3D) culture techniques
Externí odkaz:
https://doaj.org/article/009e28d5818a4aa78f74be027397bc70
Autor:
Kenjiro Namikawa, Takamichi Ito, Shusuke Yoshikawa, Koji Yoshino, Yukiko Kiniwa, Shuichi Ohe, Taiki Isei, Tatsuya Takenouchi, Hiroshi Kato, Satoru Mizuhashi, Satoshi Fukushima, Yosuke Yamamoto, Takashi Inozume, Yasuhiro Fujisawa, Osamu Yamasaki, Yasuhiro Nakamura, Jun Asai, Takeo Maekawa, Takeru Funakoshi, Shigeto Matsushita, Eiji Nakano, Kohei Oashi, Junji Kato, Hisashi Uhara, Takuya Miyagawa, Hiroshi Uchi, Naohito Hatta, Keita Tsutsui, Taku Maeda, Taisuke Matsuya, Hiroto Yanagisawa, Ikko Muto, Mao Okumura, Dai Ogata, Naoya Yamazaki
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 17967-17980 (2023)
Abstract Background Anti‐PD‐1‐based immunotherapy is considered a preferred first‐line treatment for advanced BRAF V600‐mutant melanoma. However, a recent international multi‐center study suggested that the efficacy of immunotherapy is po
Externí odkaz:
https://doaj.org/article/7bd38e76e920444a8356acd6025d9a4c
Autor:
Hajime Nakamura, Aika Shionoya, Yohei Arihara, Naotaka Hayasaka, Tomohiro Kubo, Makoto Usami, Shintaro Sugita, Hisashi Uhara, Kohichi Takada
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Ipilimumab plus nivolumab therapy is approved for patients with unresectable advanced esophageal squamous cell carcinoma (ESCC). Although a combination of immune checkpoint inhibitors (ICIs), compared to conventional chemotherapy, can improve overall
Externí odkaz:
https://doaj.org/article/a32a04531e6a4771a5e78302cc7dbcb6
Autor:
Takuto Ogasawara, Fumimasa Fukuta, Miri Fujita, Hitoshi Tachiki, Tetsuya Shindo, Junji Kato, Hisashi Uhara, Naoya Masumori
Publikováno v:
IJU Case Reports, Vol 5, Iss 5, Pp 410-414 (2022)
Introduction Pyoderma gangrenosum is a rare dermatological disease associated with underlying inflammatory conditions. Case presentation A 59‐year‐old man was diagnosed with right renal cancer cT1aN0M0 and laparoscopic right radical nephrectomy w
Externí odkaz:
https://doaj.org/article/ff9f093b7b4d41249f2e02afb111511e
Publikováno v:
Allergology International, Vol 71, Iss 3, Pp 409-411 (2022)
Externí odkaz:
https://doaj.org/article/cf32f4bcaa0e40b9b85a7819e9bb8a76
Autor:
Terufumi Kubo, Sayuri Sato, Tokimasa Hida, Tomoyuki Minowa, Yoshihiko Hirohashi, Tomohide Tsukahara, Takayuki Kanaseki, Kenji Murata, Hisashi Uhara, Toshihiko Torigoe
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 3, Pp 734-745 (2021)
Abstract Background Barrier disruption and an excessive immune response in keratinocytes are now considered to have important roles in the pathophysiology of atopic dermatitis (AD). Furthermore, disturbed keratinocyte differentiation is considered to
Externí odkaz:
https://doaj.org/article/38156c2cf35646e2b075010a091cfa70
Publikováno v:
Dermatology Practical & Conceptual, Vol 12, Iss 3 (2022)
Externí odkaz:
https://doaj.org/article/f7a5e84412b848dfa9da627e21d8e87b
Autor:
Hiroshi Ohguro, Megumi Watanabe, Tatsuya Sato, Fumihito Hikage, Masato Furuhashi, Masae Okura, Tokimasa Hida, Hisashi Uhara
Publikováno v:
Cells, Vol 12, Iss 5, p 759 (2023)
To study the molecular mechanisms responsible for inducing the spatial proliferation of malignant melanomas (MM), three-dimension (3D) spheroids were produced from several MM cell lines including SK-mel-24, MM418, A375, WM266-4, and SM2-1, and their
Externí odkaz:
https://doaj.org/article/329985a6072342a6a4559b90f7746be7