Výsledky vyhledávání - "HISAKO YAMAGUCHI"

Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease

Autor: Mauro Fa, Ariel Hidalgo, Hong Zhang, Shumin Liu, Paul M. Mathews, Ottavio Arancio, Narihiko Yoshii, Ralph A. Nixon, Hisako Yamaguchi, Stephen D. Schmidt, Fabrizio Trinchese

Publikováno v: Journal of Clinical Investigation. 118:2796-2807

Calpains are calcium-dependent enzymes that determine the fate of proteins through regulated proteolytic activity. Calpains have been linked to the modulation of memory and are key to the pathogenesis of Alzheimer disease (AD). When abnormally activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94e7afcf0c679b4ae50db3fc1921fe4
https://doi.org/10.1172/jci34254

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Effects of Long Term Administration of 2-Amino-4,5-Diphenylthiazole on Kidneys in Rats and N-Ethyl-N-Hydroxyethylnitrosamine-Treated Rats

Autor: Yoshihiro Motomiya, Yoshiteru Kitahori, Seiichiro Ozono, Eigoro Okajima, Yoshio Hiasa, Kenichi Tsumatani, Hirotsugu Uemura, Yoshihiko Hirao, Hiroaki Okabe, Hisako Yamaguchi, Yoshinori Uji

Publikováno v: Journal of Toxicologic Pathology. 9:151-159

Changes in the kidneys were studied histopathologically and biochemically in F344 rats treated for long periods with 2-amino-4, 5-diphenylthiazole (DPT), with and without prior application of the renal carcinogen N-ethyl-N-hydroxyethylnitrosamine (EH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31e05f1428b5015875bce171922de168
https://doi.org/10.1293/tox.9.151

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Inhibitory effects of combination chemotherapeutic regimens on mouse bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine

Autor: Hisayo Kitagawa, Seiichiro Ozono, Yoshiki Hayashi, M Yoshikawa, Matsuki H, Tatsuo Yoneda, Kenji Takashima, Eigoro Okajima, Yoshihiko Hirao, Hisako Yamaguchi

Publikováno v: Journal of Toxicologic Pathology. 9:43-49

Experiment I was conducted to examine the optimum duration of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) for studying promoters and inhibitors of mouse bladder carcinogenesis in mice. When the mice were treated with 0.05% BBN for 12 weeks and subse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46eb63d43d0fbdfc0849461aa28f8df8
https://doi.org/10.1293/tox.9.43

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Basic Fibroblast Growth Factor as a Candidate Tumor Marker for Renal Cell Carcinoma

Autor: Masaaki Terada, Tadao Kakizoe, Eigoro Okajima, Takashi Futami, Seiichiro Ozono, Hisako Yamaguchi, Yuzo Ichimori, Kunihiko Arai, Yoshihiko Hirao, Kiyohide Fujimoto

Publikováno v: Japanese Journal of Cancer Research : Gann

The present investigation was conducted to determine serum levels of basic fibroblast growth factor (FGF) by enzyme immunoassay in patients with various urogenital tumors. Renal cell carcinoma had a higher tendency (28 of 52, 53.8%) toward increased

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fdd34c7979c55a6fa8fea30bdce0f9
https://doi.org/10.1111/j.1349-7006.1995.tb03037.x

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Histopathological findings of the urinary bladder epithelium in aged dogs

Autor: Babaya K, Yoshiki Hayashi, Kunihiko Tsunemi, Shoji Fukushima, Yoshihiko Hirao, Hisako Yamaguchi, Eigoro Okajima, Seiichiro Ozono, Rikio Niki

Publikováno v: Journal of Toxicologic Pathology. 7:73-80

Apparently normal urinary bladder of beagle dogs of both sexes were examined histopathologically. Materials were obtained from fifty autopsied aged beagle dogs and six autopsied young beagle dogs. Changes of urinary bladder epithelium were classified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcf8127e4d4ca30c763de1efd23c85f0
https://doi.org/10.1293/tox.7.73

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Effects of combination chemotherapy including cyclophosphamide, thpadriamycin, and cisplatin on the development of urinary bladder carcinoma induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in rats

Autor: Tabata S, Seiichiro Ozono, Shoji Samma, Yoshihiko Hirao, Eigoro Okajima, Kunihiko Tsunemi, Matsuki H, Yoshiki Hayashi, Hisayo Kitagawa, Hisako Yamaguchi

Publikováno v: Journal of Toxicologic Pathology. 5:61-66

The present investigation was conducted to examine the effects of combination chemotherapy including Cyclophosphamide (CPM), THP-adriamycin (THP), and Cisplatin (CDDP) (CTP regimen) on the development of urinary bladder carcinoma induced by N-butyl-N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d434eff59ddf1f827043400bfafb0bc
https://doi.org/10.1293/tox.5.61

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Effects of various chemicals on the development of mouse urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine

Autor: Seiichiro Ozono, Hisako Yamaguchi, Matsuki H, Eigoro Okajima, Masato Ohshima, Yoshio Hiasa, Yoshihiko Hirao, Yoshiteru Kitahori, Kunihiko Tsunemi

Publikováno v: Journal of Toxicologic Pathology. 5:55-60

Effects of various chemicals on the development of urinary bladder tumors in mouse treated with N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) were examined, Male C3H/He mice received 0.05% BBN in drinking water for 8 weeks, and were subsequently treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03ef183d2226c8904bc22283cf9ddad0
https://doi.org/10.1293/tox.5.55

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