Zobrazeno 1 - 10
of 132
pro vyhledávání: '"HIRST, DAVID G."'
Autor:
Al-Assar, Osama, Robson, Tracy, McKeown, Stephanie R., Gardin, Isabelle, Wilson, George D., Hirst, David G.
Publikováno v:
Radiation Research, 2000 Nov 01. 154(5), 503-514.
Externí odkaz:
https://www.jstor.org/stable/3580660
Autor:
Jain, Suneil, Coulter, Jonathan A., Butterworth, Karl T., Hounsell, Alan R., McMahon, Stephen J., Hyland, Wendy B., Muir, Mark F., Dickson, Glenn R., Prise, Kevin M., Currell, Fred J., Hirst, David G., O’Sullivan, Joe M.
Publikováno v:
In Radiotherapy and Oncology February 2014 110(2):342-347
Autor:
Jain, Suneil, Coulter, Jonathan A., Hounsell, Alan R., Butterworth, Karl T., McMahon, Stephen J., Hyland, Wendy B., Muir, Mark F., Dickson, Glenn R., Prise, Kevin M., Currell, Fred J., O’Sullivan, Joe M., Hirst, David G.
Publikováno v:
In International Journal of Radiation Oncology, Biology, Physics 2011 79(2):531-539
The Modification of Hemoglobin Affinity for Oxygen and Tumor Radiosensitivity by Antilipidemic Drugs
Publikováno v:
Radiation Research, 1987 Oct 01. 112(1), 164-172.
Externí odkaz:
https://www.jstor.org/stable/3577087
Publikováno v:
Radiation Research, 1979 Feb 01. 77(2), 259-275.
Externí odkaz:
https://www.jstor.org/stable/3575138
Autor:
Sun, Zhonghua ∗, Winder, John R., Kelly, Barry E., Ellis, Peter K., Kennedy, Peter T., Hirst, David G.
Publikováno v:
In Computerized Medical Imaging and Graphics 2004 28(1):3-12
Autor:
McCrudden, Cian M., O’Rourke, Martin G., Cherry, Kim E., Yuen, Hiu-Fung, O’Rourke, Declan, Babur, Muhammad, Telfer, Brian A., Thomas, Huw D., Keane, Patrick, Nambirajan, Thiagarajan, Hagan, Chris, O’Sullivan, Joe M., Shaw, Chris, Williams, Kaye J., Curtin, Nicola J., Hirst, David G., Robson, Tracy
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118187 (2015)
McCrudden, C M, O'Rourke, M G, Cherry, K E, Yuen, H-F, O'Rourke, D, Babur, M, Telfer, B A, Thomas, H D, Keane, P, Nambirajan, T, Hagan, C, O'Sullivan, J M, Shaw, C, Williams, K J, Curtin, N J, Hirst, D G & Robson, T 2015, ' Vasoactivity of Rucaparib, a PARP-1 Inhibitor, is a Complex Process that Involves Myosin Light Chain Kinase, P2 Receptors, and PARP Itself ', PloS one, vol. 10, no. 2, e0118187 . https://doi.org/10.1371/journal.pone.0118187
PLoS ONE
McCrudden, C M, O'Rourke, M G, Cherry, K E, Yuen, H-F, O'Rourke, D, Babur, M, Telfer, B A, Thomas, H D, Keane, P, Nambirajan, T, Hagan, C, O'Sullivan, J M, Shaw, C, Williams, K J, Curtin, N J, Hirst, D G & Robson, T 2015, ' Vasoactivity of Rucaparib, a PARP-1 Inhibitor, is a Complex Process that Involves Myosin Light Chain Kinase, P2 Receptors, and PARP Itself ', PloS one, vol. 10, no. 2, e0118187 . https://doi.org/10.1371/journal.pone.0118187
PLoS ONE
Therapeutic inhibition of poly(ADP-ribose) polymerase (PARP), as monotherapy or to supplement the potencies of other agents, is a promising strategy in cancer treatment. We previously reported that the first PARP inhibitor to enter clinical trial, ru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d841cee3e4ddb244be3e5c43ea91727e
http://europepmc.org/articles/PMC4331495?pdf=render
http://europepmc.org/articles/PMC4331495?pdf=render
Autor:
Ali, Ahlam A., Coulter, Jonathan A., Ogle, Claire H., Migaud, Marie M., Hirst, David G., Robson, Tracy, McCarthy, Helen O.
Publikováno v:
Ali, A A, Coulter, J A, Ogle, C H, Migaud, M M, Hirst, D G, Robson, T & McCarthy, H O 2013, ' The contribution of N₂O₃ to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation ', Bioscience Reports, vol. 33, no. 2, pp. 333-349 . https://doi.org/10.1042/BSR20120120
The relationship between the biological activity of NO and its chemistry is complex. The objectives of this study were to investigate the influence of oxygen tension on the cytotoxicity of the NO• donor DETA/NO and to determine the effects of oxyge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2607::c7d67f9b4970d14fafc6486d3d7398d9
https://pure.qub.ac.uk/en/publications/the-contribution-of-no-to-the-cytotoxicity-of-the-nitric-oxide-donor-detano-an-emerging-role-for-snitrosylation(be608b1f-9c9f-4ed4-b14b-634c59e6316e).html
https://pure.qub.ac.uk/en/publications/the-contribution-of-no-to-the-cytotoxicity-of-the-nitric-oxide-donor-detano-an-emerging-role-for-snitrosylation(be608b1f-9c9f-4ed4-b14b-634c59e6316e).html
Akademický článek
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Autor:
Senra, Joana M., Telfer, Brian A., Cherry, Kim E., McCrudden, Cian M., Hirst, David G., O’Connor, Mark J., Wedge, Stephen R., Stratford, Ian J.
PARP-1 is a critical enzyme in the repair of DNA strand breaks. Inhibition of PARP-1 increases the effectiveness of radiation in killing tumor cells. However, although the mechanism(s) are well understood for these radiosensitizing effects in vitro,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2408fec13d076aec02bc237fb3a1c517
https://europepmc.org/articles/PMC3192032/
https://europepmc.org/articles/PMC3192032/