Zobrazeno 1 - 10
of 312
pro vyhledávání: '"HIROYUKI AOKI"'
Autor:
May G. Akl, Lei Li, Raquel Baccetto, Sadhna Phanse, Qingzhou Zhang, Michael J. Trites, Sherin McDonald, Hiroyuki Aoki, Mohan Babu, Scott B. Widenmaier
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112872- (2023)
Externí odkaz:
https://doaj.org/article/5bb871cfb9264e10b2711ed1ac3c4ac2
Autor:
Michael J. Trites, Brynne M. Stebbings, Hiroyuki Aoki, Sadhna Phanse, May G. Akl, Lei Li, Mohan Babu, Scott B. Widenmaier
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
High density lipoproteins (HDL) promote homeostasis and counteract stressful tissue damage that underlie cardiovascular and other diseases by mediating reverse cholesterol transport, reducing inflammation, and abrogating oxidative damage. However, me
Externí odkaz:
https://doaj.org/article/2ccfdfc990194e93bf9d94ebaf85d8ba
Autor:
Alla Gagarinova, Ali Hosseinnia, Matineh Rahmatbakhsh, Zoe Istace, Sadhna Phanse, Mohamed Taha Moutaoufik, Mara Zilocchi, Qingzhou Zhang, Hiroyuki Aoki, Matthew Jessulat, Sunyoung Kim, Khaled A. Aly, Mohan Babu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The bacterium E. coli has around 300 transcriptional factors, but the functions of many of them, and the interactions between their respective regulatory networks, are unclear. Here, the authors study genetic interactions among all transcription fact
Externí odkaz:
https://doaj.org/article/e26b507a74f145268dd8fb6fa76b67a2
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Neutron reflectometry (NR) allows us to probe into the structure of the surfaces and interfaces of various materials such as soft matters and magnetic thin films with a contrast mechanism dependent on isotopic and magnetic states. The neutro
Externí odkaz:
https://doaj.org/article/d168e5a353f1460c89ea1c0ecd10bf71
Autor:
Vladimir Vélez-Segarra, Sahily González-Crespo, Ednalise Santiago-Cartagena, Luis E. Vázquez-Quiñones, Nelson Martínez-Matías, Yamirelis Otero, Julián J. Zayas, Rafael Siaca, Jeanmadi del Rosario, Inoushka Mejías, José J. Aponte, Noelani C. Collazo, Francisco J. Lasso, Jamie Snider, Matthew Jessulat, Hiroyuki Aoki, Brian C. Rymond, Mohan Babu, Igor Stagljar, José R. Rodríguez-Medina
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3121-3135 (2020)
Antifungal drug discovery and design is very challenging because of the considerable similarities in genetic features and metabolic pathways between fungi and humans. However, cell wall composition represents a notable point of divergence. Therefore,
Externí odkaz:
https://doaj.org/article/213888786ea440eeb78f0cdc64041d9e
Autor:
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
Publikováno v:
iScience, Vol 19, Iss , Pp 1114-1132 (2019)
Summary: Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-ba
Externí odkaz:
https://doaj.org/article/c6301e8c20a347908830d745496bf253
Autor:
Ednalise Santiago-Cartagena, Sahily González-Crespo, Vladimir Vélez, Nelson Martínez, Jamie Snider, Matthew Jessulat, Hiroyuki Aoki, Zoran Minic, Pearl Akamine, Inoushka Mejías, Luis M. Pérez, Brian C. Rymond, Mohan Babu, Igor Stagljar, José R. Rodríguez-Medina
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 4, Pp 1085-1102 (2019)
Wsc1p and Mid2p are transmembrane signaling proteins of cell wall stress in the budding yeast Saccharomyces cerevisiae. When an environmental stress compromises cell wall integrity, they activate a cell response through the Cell Wall Integrity (CWI)
Externí odkaz:
https://doaj.org/article/f845c816eff5461386fe7b01eea6966f
Autor:
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 3, Pp 1-19 (2017)
Abstract G‐protein‐coupled receptors (GPCRs) are the largest family of integral membrane receptors with key roles in regulating signaling pathways targeted by therapeutics, but are difficult to study using existing proteomics technologies due to
Externí odkaz:
https://doaj.org/article/8967c8058cf7455eb51b7bdd45452e18
Autor:
Alla Gagarinova, Geordie Stewart, Bahram Samanfar, Sadhna Phanse, Carl A. White, Hiroyuki Aoki, Viktor Deineko, Natalia Beloglazova, Alexander F. Yakunin, Ashkan Golshani, Eric D. Brown, Mohan Babu, Andrew Emili
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 904-916 (2016)
Bacterial protein synthesis is an essential, conserved, and environmentally responsive process. Yet, many of its components and dependencies remain unidentified. To address this gap, we used quantitative synthetic genetic arrays to map functional rel
Externí odkaz:
https://doaj.org/article/dac41ea360a046c5a5f5850ed06d8be2
Autor:
Ednalise Santiago, Pearl Akamine, Jamie Snider, Victoria Wong, Matthew Jessulat, Viktor Deineko, Alla Gagarinova, Hiroyuki Aoki, Zoran Minic, Sadhna Phanse, Andrea San Antonio, Luis A. Cubano, Brian C. Rymond, Mohan Babu, Igor Stagljar, Jose R. Rodriguez-Medina
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 5, Pp 1469-1474 (2016)
Nonmuscle myosin type II (Myo1p) is required for cytokinesis in the budding yeast Saccharomyces cerevisiae. Loss of Myo1p activity has been associated with growth abnormalities and enhanced sensitivity to osmotic stress, making it an appealing antifu
Externí odkaz:
https://doaj.org/article/57d4a251d67b42f4ab2e949e60cb2267