Zobrazeno 1 - 10
of 214
pro vyhledávání: '"HIROSHI NONOGUCHI"'
Publikováno v:
Molecules, Vol 28, Iss 11, p 4446 (2023)
Detection of erythropoietin (Epo) was difficult until a method was developed by the World Anti-Doping Agency (WADA). WADA recommended the Western blot technique using isoelectric focusing (IEF)-PAGE to show that natural Epo and injected erythropoiesi
Externí odkaz:
https://doaj.org/article/222b398af8554ed08a7072b269486924
Autor:
Yukiko Yasuoka, Takashi Fukuyama, Yuichiro Izumi, Tetsuro Yamashita, Yushi Nakayama, Hideki Inoue, Kengo Yanagita, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Masashi Mukoyama, Yuichi Sato, Jeff M. Sands, Katsumasa Kawahara, Hiroshi Nonoguchi
Publikováno v:
Heliyon, Vol 6, Iss 11, Pp e05389- (2020)
Doping tests for the illegal use of erythropoiesis-stimulating agents (ESAs) have been developed. We developed a new Western blotting method to detect and distinguish endogenous erythropoietin (Epo, 35-38 kDa) and exogenous ESAs (epoetin α and β, 3
Externí odkaz:
https://doaj.org/article/e4e48d4cbd494a719c9eb3d4572c3279
Autor:
Yukiko Yasuoka, Takashi Fukuyama, Yuichiro Izumi, Yushi Nakayama, Hideki Inoue, Kengo Yanagita, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Masashi Mukoyama, Tetsuro Yamashita, Yuichi Sato, Jeff M. Sands, Katsumasa Kawahara, Hiroshi Nonoguchi
Publikováno v:
Physiological Reports, Vol 8, Iss 12, Pp n/a-n/a (2020)
Abstract The detection of erythropoietin (Epo) protein by Western blotting has required pre‐purification of the sample. We developed a new Western blot method to detect plasma and urinary Epo using deglycosylation. Epo in urine and tissue, and eryt
Externí odkaz:
https://doaj.org/article/5ec73d617102476aa3f117aab7606d78
Autor:
Yukiko Yasuoka, Yuichiro Izumi, Takashi Fukuyama, Haruki Omiya, Truyen D. Pham, Hideki Inoue, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Tetsuro Yamashita, Masashi Mukoyama, Yuichi Sato, Susan M. Wall, Jeff M. Sands, Noriko Takahashi, Katsumasa Kawahara, Hiroshi Nonoguchi
Publikováno v:
Molecules, Vol 27, Iss 3, p 1119 (2022)
Anemia is a major complication of chronic renal failure. To treat this anemia, prolylhydroxylase domain enzyme (PHD) inhibitors as well as erythropoiesis-stimulating agents (ESAs) have been used. Although PHD inhibitors rapidly stimulate erythropoiet
Externí odkaz:
https://doaj.org/article/454c38365a2d421d94587e564812c29b
Autor:
Yukiko Yasuoka, Yuichiro Izumi, Takashi Fukuyama, Hideki Inoue, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Masashi Mukoyama, Yuichi Sato, Jeff M Sands, Katsumasa Kawahara, Hiroshi Nonoguchi
Publikováno v:
Molecules, Vol 26, Iss 17, p 5399 (2021)
The kidney is a main site of erythropoietin production in the body. We developed a new method for the detection of Epo protein by deglycosylation-coupled Western blotting. Detection of deglycosylated Epo enables the examination of small changes in Ep
Externí odkaz:
https://doaj.org/article/53b4ec3a22984384821c45b5bf2f1e37
Autor:
Yuichiro Izumi, Hideki Inoue, Yushi Nakayama, Koji Eguchi, Yukiko Yasuoka, Naomi Matsuo, Hiroshi Nonoguchi, Yutaka Kakizoe, Takashige Kuwabara, Masashi Mukoyama
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0184185 (2017)
Metabolic acidosis often results from chronic kidney disease; in turn, metabolic acidosis accelerates the progression of kidney injury. The mechanisms for how acidosis facilitates kidney injury are not fully understood. To investigate whether low pH
Externí odkaz:
https://doaj.org/article/287c862eae4b4dd69d0528585e3cbfbe
Autor:
Hiroshi Nonoguchi, Yuichiro Izumi, Yushi Nakayama, Takanobu Matsuzaki, Yukiko Yasuoka, Takeaki Inoue, Hideki Inoue, Tomohiko Mouri, Katsumasa Kawahara, Hideyuki Saito, Kimio Tomita
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83146 (2013)
Atrial natriuretic peptide (ANP) is known to influence NaCl transport in the medullary thick ascending limbs (MAL), where the largest NaCl reabsorption occurs among distal nephron segments in response to arginine vasopressin (AVP). In the present stu
Externí odkaz:
https://doaj.org/article/f3aa19cdced24004a64f30917646aa0a
Autor:
Makoto Ono, Yuichiro Izumi, Kosuke Maruyama, Yukiko Yasuoka, Akiko Hiramatsu, Jose Aramburu, López-Rodríguez, Cristina, Hiroshi Nonoguchi, Yutaka Kakizoe, Masataka Adachi, Takashige Kuwabara, Masashi Mukoyama
Publikováno v:
American Journal of Physiology: Renal Physiology; Mar2024, Vol. 326 Issue 3, pF394-F410, 17p
Autor:
Akiko Hiramatsu, Hyun-Wook Lee, Takashige Kuwabara, Makoto Ono, Yutaka Kakizoe, Terumasa Nakagawa, Kosuke Maruyama, Masashi Mukoyama, Koji Eguchi, Hideki Inoue, Hiroshi Nonoguchi, Yukiko Yasuoka, Yushi Nakayama, Naomi Matsuo, Yuichiro Izumi, I. David Weiner
Publikováno v:
J Endocrinol
Rhesus C glycoprotein (Rhcg), an ammonia transporter, is a key molecule in urinary acid excretion and is expressed mainly in the intercalated cells (ICs) of the renal collecting duct. In the present study we investigated the role of aldosterone in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb991a2544f6277ef6c904a6984e0d30
https://doi.org/10.1530/joe-20-0267
https://doi.org/10.1530/joe-20-0267
Autor:
Yuichiro Izumi, Akiko Hiramatsu, Koji Eguchi, Naomi Matsuo, Qinyuan Deng, Hideki Inoue, Yushi Nakayama, Hiroshi Nonoguchi, Jose Aramburu, Cristina Lopez Rodriguez, Yutaka Kakizoe, Masataka Adachi, Takashige Kuwabara, Shokei Kim Mitsuyama, Masashi Mukoyama
Publikováno v:
Journal of Hypertension. 41:e289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f909655f59916b20daaae4ba0c37f81
https://doi.org/10.1097/01.hjh.0000915680.17528.f3
https://doi.org/10.1097/01.hjh.0000915680.17528.f3