Zobrazeno 1 - 10
of 1 419
pro vyhledávání: '"HIRONOBU SASANO"'
Autor:
Nattaya Duangthim, Thanpisit Lomphithak, Ryoko Saito-Koyama, Yasuhiro Miki, Chihiro Inoue, Ikuro Sato, Eisaku Miyauchi, Jiro Abe, Hironobu Sasano, Siriporn Jitkaew
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Lung cancer remains the leading cause of cancer death. Treatment with immune checkpoint inhibitor (ICI) alone or combination with chemotherapy served as first-line therapy in non-small cell lung cancer (NSCLC). However, only 20–50% of NSCL
Externí odkaz:
https://doaj.org/article/1ce6124ece9c48e5b0eda25e78fa7ddd
Autor:
Sawako Suzuki, Naoya Takahashi, Masafumi Sugo, Kazuki Ishiwata, Akiko Ishida, Suzuka Watanabe, Katsushi Igarashi, Yutaro Ruike, Kumiko Naito, Masanori Fujimoto, Hisashi Koide, Yusuke Imamura, Shinichi Sakamoto, Tomohiko Ichikawa, Yoshihiro Kubota, Takeshi Wada, Yuto Yamazaki, Hironobu Sasano, Jun-ichiro Ikeda, Ichiro Tatsuno, Koutaro Yokote
Publikováno v:
BMC Endocrine Disorders, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Primary adrenal leiomyosarcoma is a rare and aggressive mesenchymal tumor derived from the smooth muscle wall of a central adrenal vein or its tributaries; therefore, tumors tend to invade the inferior vena cava and cause thrombos
Externí odkaz:
https://doaj.org/article/8d25404402344005a38c945f26ae5732
Identifying primary aldosteronism patients who require adrenal venous sampling: a multi-center study
Autor:
Takumi Kitamoto, Tsuyoshi Idé, Yuta Tezuka, Norio Wada, Yui Shibayama, Yuya Tsurutani, Tomoko Takiguchi, Kosuke Inoue, Sachiko Suematsu, Kei Omata, Yoshikiyo Ono, Ryo Morimoto, Yuto Yamazaki, Jun Saito, Hironobu Sasano, Fumitoshi Satoh, Tetsuo Nishikawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Adrenal venous sampling (AVS) is crucial for subtyping primary aldosteronism (PA) to explore the possibility of curing hypertension. Because AVS availability is limited, efforts have been made to develop strategies to bypass it. However, it
Externí odkaz:
https://doaj.org/article/f80bebafd2a14fb49de24e560300bf9c
Autor:
Habibah Faroque, Nur Soleha Aria, Nor Amira Muzilah, Hamid Ali Nagi Al-Jamal, Mohd Fadliyazid Ab. Rahim, Yasuhiro Nakamura, Hironobu Sasano, Abdullah Azmahani
Publikováno v:
Indonesian Biomedical Journal, Vol 15, Iss 6, Pp 358-65 (2023)
BACKGROUND: The checkpoint kinase 1 (CHEK1) and glutamine-fructose-6-phosphate aminotransferase 1 (GFPT1) genes have been reported to have a crucial role in carcinogenesis in colorectal cancer (CRC). However, their association with the pathogenesis o
Externí odkaz:
https://doaj.org/article/6a22dc93dbe247f18a9de9dd57657e2c
Autor:
Kazutaka Nanba, Amy R. Blinder, Aaron M. Udager, Yuusuke Hirokawa, Takayoshi Miura, Hiroshi Okuno, Koki Moriyoshi, Yuto Yamazaki, Hironobu Sasano, Akihiro Yasoda, Noriko Satoh-Asahara, William E. Rainey, Tetsuya Tagami
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Double somatic mutations in CTNNB1 and GNA11/Q have recently been identified in a small subset of aldosterone-producing adenomas (APAs). As a possible pathogenesis of APA due to these mutations, an association with pregnancy, menopause, or puberty ha
Externí odkaz:
https://doaj.org/article/f946e9d2c19542a38c90af28d8ca3ed6
Autor:
Sarah Asemota, Wendy Effah, Kirsten L. Young, Jeremiah Holt, Linnea Cripe, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Dong-Jin Hwang, Yali He, Keely Mcnamara, Daniel Johnson, Yinan Wang, Brandy Grimes, Yekta Khosrosereshki, T.J. Hollingsworth, Martin D. Fleming, Frances E. Pritchard, Ashley Hendrix, Farhan Khan, Meiyun Fan, Liza Makowski, Zheng Yin, Hironobu Sasano, D. Neil Hayes, Lawrence M. Pfeffer, Duane D. Miller, Ramesh Narayanan
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113461- (2023)
Summary: Triple-negative breast cancer (TNBC) is an aggressive subtype with no targeted therapeutics. The luminal androgen receptor (LAR) subtype constitutes 15% of TNBC and is enriched for androgen receptor (AR) and AR target genes. Here, we show th
Externí odkaz:
https://doaj.org/article/ac241ea52bf347e5b56f2020cc95e398
Autor:
Keisuke Nonaka, Kaiyo Takubo, Junko Aida, Yoriko Watai, Akiko Komatsu, Fujiya Gomi, Yuuki Shichi, Yuto Yamazaki, Toshiyuki Ishiwata, Hironobu Sasano, Tomio Arai
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundThe number of patients with prolonged critical illness (PCI) has been increasing in many countries, and the adrenal gland plays an important role in maintaining homeostasis during PCI. Chronic disease burden is reportedly associated with sh
Externí odkaz:
https://doaj.org/article/8d3eff5b9ee346f5ba26e11f15240004
Autor:
Hirofumi Watanabe, Fumiyoshi Fujishima, Toru Motoi, Yayoi Aoyama, Tetsuya Niihori, Masanobu Takahashi, Sho Umegaki, Hisashi Oishi, Hiroshi Tada, Ryo Ichinohasama, Hironobu Sasano
Publikováno v:
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-6 (2022)
Abstract Background Germline TP53 mutations have been frequently reported in patients with Li–Fraumeni syndrome (LFS), resulting in a predisposition to various malignancies. Mutations other than germline TP53 mutations can also cause LFS-associated
Externí odkaz:
https://doaj.org/article/f5fd271aa8af47869ff2081aab790de4
Autor:
Shiori Kitaya, Ryoukichi Ikeda, Jun Suzuki, Hidetoshi Oshima, Yuri Nomura, Yusuke Kusano, Nobuo Ohta, Tetsuaki Kawase, Kazue Ise, Kazuhiro Murakami, Yasuhiro Nakamura, Hironobu Sasano, Yukio Katori
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 4, Pp 1155-1163 (2022)
Abstract Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue. We asses
Externí odkaz:
https://doaj.org/article/99793fe68d064d34a5df050e648858d0
Autor:
Chihiro Inoue, Sachiko Konosu-Fukaya, Kazuhiro Murakami, Ryoko Saito-Koyama, Hirofumi Watanabe, Hideki Mitomo, Naoya Ishibashi, Takafumi Sugawara, Toshiharu Tabata, Hironobu Sasano, Yasuhiro Nakamura
Publikováno v:
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background Pulmonary carcinoid tumors rarely coexist with non-small cell lung carcinoma, and only nine cases have been reported previously. The pathogenesis and origin of these combined tumors remain unclear because of its rarity. Case prese
Externí odkaz:
https://doaj.org/article/0c424fec637a4268ae873fdc81d38663