Zobrazeno 1 - 10
of 493
pro vyhledávání: '"HIROMI KUMON"'
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Objective The detection and monitoring of DNA methylation status in circulating tumor cell DNA (ctDNA) provides critical insights into cancer diagnosis and progression. The methylation status of the Dickkopf-related protein 3 (DKK3) promoter
Externí odkaz:
https://doaj.org/article/cb696a0d271440079a650fda97afdd26
Autor:
Ai Miyamoto, Tomoko Honjo, Mirei Masui, Rie Kinoshita, Hiromi Kumon, Kazuhiro Kakimi, Junichiro Futami
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Serum autoantibody to cancer/testis antigens (CTAs) is a critical biomarker that reflects the antitumor immune response. Quantitative and multiplexed anti-CTA detection arrays can assess the immune status in tumors and monitor therapy-induced antitum
Externí odkaz:
https://doaj.org/article/bcaf913dd4dd48b0abec09758607b6c5
Autor:
Yasuhiko Hattori, Kazuhiko Kurozumi, Yoshihiro Otani, Atsuhito Uneda, Nobushige Tsuboi, Keigo Makino, Shuichiro Hirano, Kentaro Fujii, Yusuke Tomita, Tetsuo Oka, Yuji Matsumoto, Yosuke Shimazu, Hiroyuki Michiue, Hiromi Kumon, Isao Date
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0273242 (2022)
Reduced expression in immortalized cells/Dickkopf-3 (REIC/Dkk-3) is a tumor suppressor and its overexpression has been shown to exert anti-tumor effects as a therapeutic target gene in many human cancers. Recently, we demonstrated the anti-glioma eff
Externí odkaz:
https://doaj.org/article/60c3b1065683424a95b1b96535ea3c5a
Autor:
Takeshi Hirata, Seung Chol Park, Michelle T. Muldong, Christina N. Wu, Tomonori Yamaguchi, Amy Strasner, Omer Raheem, Hiromi Kumon, Robert L. Sah, Nicholas A. Cacalano, Catriona H.M. Jamieson, Christopher J. Kane, Koichi Masuda, Anna A. Kulidjian, Christina A.M. Jamieson
Publikováno v:
Asian Journal of Urology, Vol 3, Iss 4, Pp 229-239 (2016)
Objective: Bone metastasis occurs in up to 90% of men with advanced prostate cancer and leads to fractures, severe pain and therapy-resistance. Bone metastases induce a spectrum of types of bone lesions which can respond differently to therapy even w
Externí odkaz:
https://doaj.org/article/d195ba8d9f63409e98fe8b47e7c19eb8
Autor:
Hiromi Kumon, Katsumi Sasaki, Yuichi Ariyoshi, Takuya Sadahira, Shin Ebara, Takao Hiraki, Susumu Kanazawa, Hiroyuki Yanai, Masami Watanabe, Yasutomo Nasu
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2015, Iss 9, Pp 31-38 (2015)
Externí odkaz:
https://doaj.org/article/67539e179e284204be58cb9e9111e50e
Autor:
Hideo Ozawa, Toyohiko Watanabe, Katsutoshi Uematsu, Katsumi Sasaki, Miyabi Inoue, Hiromi Kumon
Publikováno v:
Indian Journal of Urology, Vol 25, Iss 1, Pp 110-115 (2009)
Objectives: A totally non-invasive transperineal urodynamic technique using Doppler ultrasonography has been developed. Methods: Since normal urine does not have blood cells, urine was thought not to produce the Doppler effects. However, basic studie
Externí odkaz:
https://doaj.org/article/138f495fee424016848915b5fb345d19
Autor:
Kazuko Kobayashi, Takanori Sasaki, Fumiaki Takenaka, Hiromasa Yakushiji, Yoshihiro Fujii, Yoshiro Kishi, Shoichi Kita, Lianhua Shen, Hiromi Kumon, Eiji Matsuura
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Mesothelin (MSLN) is a 40-kDa cell differentiation-associated glycoprotein appearing with carcinogenesis and is highly expressed in many human cancers, including the majority of pancreatic adenocarcinomas, ovarian cancers, and mesotheliomas, while it
Externí odkaz:
https://doaj.org/article/aa317d0d67164e9c9b72e6c181ff31dd
Autor:
Kazuhiko Shien, Norimitsu Tanaka, Masami Watanabe, Junichi Soh, Masakiyo Sakaguchi, Keitaro Matsuo, Hiromasa Yamamoto, Masashi Furukawa, Hiroaki Asano, Kazunori Tsukuda, Yasutomo Nasu, Nam-Ho Huh, Shinichiro Miyoshi, Hiromi Kumon, Shinichi Toyooka
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87900 (2014)
REIC/Dkk-3 is down-regulated in a broad range of human cancer cells and is considered to function as a tumor suppressor. We previously reported that REIC/Dkk-3-expressing adenovirus vector (Ad-REIC) induced endoplasmic reticulum (ER) stress and cance
Externí odkaz:
https://doaj.org/article/ac58e6e1567d4e58828818b1e6530d1b
Autor:
Motoo Araki, Shinya Uehara, Katsumi Sasaki, Koichi Monden, Masaya Tsugawa, Toyohiko Watanabe, Manoji Monga, Yasutomo Nasu, Hiromi Kumon
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e36729 (2012)
OBJECTIVE: To analyze the short and long term safety and efficacy of ureteroscopic evaluation and management of chronic unilateral hematuria. METHODS: We retrospectively reviewed patients with chronic unilateral hematuria from 1987 to 2008. The dista
Externí odkaz:
https://doaj.org/article/3917676db28c46429aad06d60796a91c
Autor:
Mayuko Yamamoto, Eisaku Kondo, Makoto Takeuchi, Akira Harashima, Takeshi Otani, Kazue Tsuji-Takayama, Fumiyuki Yamasaki, Hiromi Kumon, Masayoshi Kibata, Shuji Nakamura
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16841 (2011)
MicroRNAs (miRNAs) play important roles in regulating post-transcriptional gene repression in a variety of immunological processes. In particular, much attention has been focused on their roles in regulatory T (Treg) cells which are crucial for maint
Externí odkaz:
https://doaj.org/article/0a88a4b275e441f98dc7bb1dfd6e91ae