Zobrazeno 1 - 10
of 390
pro vyhledávání: '"HIROKI ISHIKAWA"'
Autor:
Melissa M. Matthews, Tae Gyun Kim, Keon Young Kim, Vladimir Meshcheryakov, Higor Alves Iha, Miho Tamai, Daiki Sasaki, Paola Laurino, Saacnicteh Toledo-Patiño, Mary Collins, Tzung-Yang Hsieh, Satoshi Shibata, Noriko Shibata, Fumiko Obata, Jun Fujii, Toshihiro Ito, Hiroshi Ito, Hiroki Ishikawa, Matthias Wolf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Initial studies on the immunogenicity of SARS-CoV-2 (CoV-2) S glycoprotein (“spike”) as a protein subunit vaccine suggested sub-optimal efficacy in mammals. Although protein engineering efforts have produced CoV-2 spike protein sequences
Externí odkaz:
https://doaj.org/article/0177c76b3d834a7fb816ba77c81efaed
Autor:
Hiroki Okamura, Hiroki Ishikawa, Takuya Ohno, Kei Nagasaki, Shogo Fujita, Shigeo Yamakami, Shota Yamamoto, Yoshifumi Kudo
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background This study aimed to examine whether the non-weight-bearing tunnel view X-ray is effective for short-term evaluation of medial meniscus posterior root tear (MMPRT) by assessing the X-ray characteristics at the initial and follow-up
Externí odkaz:
https://doaj.org/article/26a01f1e8fe14b83be89bc891b3a5724
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Fenestranes, in which four rings share one carbon atom, have garnered much attention because of their flattened quaternary carbon centers. In addition, the rigid and nonplanar structures of heteroatom-containing fenestranes are attractive sc
Externí odkaz:
https://doaj.org/article/33f73d63735e4f7e9fd7ca5cec392bb3
Autor:
Ryota Okazaki, Shino Arita, Hinako Hoshio, Naoki Uetani, Genki Inui, Hiroki Ishikawa, Takafumi Nonaka, Hiroki Kohno, Yoshihiro Funaki, Tomoya Harada, Masato Morita, Akira Watanabe, Akira Yamasaki
Publikováno v:
Respiratory Medicine Case Reports, Vol 51, Iss , Pp 102092- (2024)
A 61-year-old woman, hospitalized for a persistent cough and dyspnea, had no history of bronchial asthma, but was undergoing chemotherapy for methotrexate-related lymphoproliferative disorder due to rheumatoid arthritis. Her peripheral blood eosinoph
Externí odkaz:
https://doaj.org/article/470fe1b8ffa5410d83e953ceb304626c
Autor:
Tomoya Harada, Naoki Uetani, Genki Inui, Hiroki Ishikawa, Yoshihiro Funaki, Miki Takata, Ryota Okazaki, Kosuke Yamaguchi, Masato Morita, Shin Kitatani, Akira Yamasaki
Publikováno v:
Respiratory Medicine Case Reports, Vol 49, Iss , Pp 102035- (2024)
Pembrolizumab is an anti-programmed cell death-1 (PD-1) antibody used to treat various cancer types. Treatments with such immune checkpoint inhibitors cause immune-related adverse events. However, airway inflammation caused by immune-related adverse
Externí odkaz:
https://doaj.org/article/502951899a09431bbebdd12385644ead
Autor:
Masato Hirota, Miho Tamai, Sachie Yukawa, Naoyuki Taira, Melissa M. Matthews, Takeshi Toma, Yu Seto, Makiko Yoshida, Sakura Toguchi, Mio Miyagi, Tomoari Mori, Hiroaki Tomori, Osamu Tamai, Mitsuo Kina, Eishin Sakihara, Chiaki Yamashiro, Masatake Miyagi, Kentaro Tamaki, Matthias Wolf, Mary K. Collins, Hiroaki Kitano, Hiroki Ishikawa
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract COVID-19 mRNA vaccines induce protective adaptive immunity against SARS-CoV-2 in most individuals, but there is wide variation in levels of vaccine-induced antibody and T-cell responses. However, the mechanisms underlying this inter-individu
Externí odkaz:
https://doaj.org/article/9fb7d2d5967948fd8e666550ffc357a4
Autor:
Aditya Sri Listyoko, Ryota Okazaki, Tomoya Harada, Miki Takata, Masato Morita, Hiroki Ishikawa, Yoshihiro Funaki, Akira Yamasaki
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 712 (2024)
Background: Tocotrienols exhibit antioxidant and anti-inflammatory activities. RhoA, a small GTPase protein, plays a crucial role in regulating contractility in airway smooth muscle (ASM). Previous studies have demonstrated that γ-tocotrienols reduc
Externí odkaz:
https://doaj.org/article/dc76527479f94127a7ce3c32270963fc
Autor:
Chikara Kohda, Satoshi Ino, Hiroki Ishikawa, Yoshihiro Kuno, Ryuichi Nagashima, Masayuki Iyoda
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Human cytomegalovirus (HCMV) is a member of Herpesviridae. It has been reported that HCMV is reactivated in the breast milk of HCMV-seropositive lactating women. As we have reported various aspects of the roles of indigenous microbiota, its
Externí odkaz:
https://doaj.org/article/09db64fb845c403bb0168dbd1800fd87
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Hypoxia-inducible factor-prolyl hydroxylase (HIF-PHD) inhibitors are therapeutic agents for renal anemia that work through HIF2-mediated upregulation of erythropoietin (EPO) and have also been reported to suppress renal fibrosis. Group 2 inn
Externí odkaz:
https://doaj.org/article/664a47abb5be49738020ad4af95f8038
Autor:
Naoyuki Taira, Sakura Toguchi, Mio Miyagi, Tomoari Mori, Hiroaki Tomori, Koichi Oshiro, Osamu Tamai, Mitsuo Kina, Masatake Miyagi, Kentaro Tamaki, Mary K Collins, Hiroki Ishikawa
Publikováno v:
Clinical Immunology Communications, Vol 2, Iss , Pp 6-11 (2022)
Pre-existing SARS-CoV-2-specific T cells, but not antibodies, have been detected in some unexposed individuals. This may account for some of the diversity in clinical outcomes ranging from asymptomatic infection to severe COVID-19. Although age is a
Externí odkaz:
https://doaj.org/article/7637bee6a98342198adfe285be5888d3