Zobrazeno 1 - 10
of 434
pro vyhledávání: '"HIROHISA YANO"'
Autor:
Kosuke Ueda, Keiichiro Uemura, Naoki Ito, Yuya Sakai, Satoshi Ohnishi, Hiroki Suekane, Hirofumi Kurose, Tasuku Hiroshige, Katsuaki Chikui, Kiyoaki Nishihara, Makoto Nakiri, Shigetaka Suekane, Sachiko Ogasawara, Hirohisa Yano, Tsukasa Igawa
Publikováno v:
Current Oncology, Vol 31, Iss 4, Pp 1701-1712 (2024)
Immuno-oncology (IO) combination therapy is the first-line treatment for advanced renal cell carcinoma (RCC). However, biomarkers for predicting the response to IO combination therapy are lacking. Here, we investigated the association between the exp
Externí odkaz:
https://doaj.org/article/11f53d13330b4e1285ae6a5190539e9a
Autor:
Hideki Iwamoto, Hiroyuki Suzuki, Atsutaka Masuda, Takahiko Sakaue, Toru Nakamura, Toshimitsu Tanaka, Miwa Sakai, Yasuko Imamura, Hirohisa Yano, Takuji Torimura, Hironori Koga, Kaori Yasuda, Masakatsu Tsurusaki, Takahiro Seki, Takumi Kawaguchi
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108797- (2024)
Summary: Current approved anti-angiogenic drugs (AAD) for hepatocellular carcinoma (HCC) inhibit tumor angiogenesis, but affect the hepatic vasculature resulting in adverse effects. Tumor endothelial cells (TECs) differ from normal endothelial cells.
Externí odkaz:
https://doaj.org/article/031aaec1a390453d82be69fc0ff3cd30
Autor:
Hiroyuki Suzuki, Hideki Iwamoto, Takahiro Seki, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Yasuko Imamura, Takashi Niizeki, Masahito Nakano, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Miwa Sakai, Kazutoyo Morita, Masamichi Nakayama, Tomoharu Yoshizumi, Ryoko Kuromatsu, Hirohisa Yano, Yihai Cao, Hironori Koga, Takuji Torimura
Publikováno v:
Cancer Communications, Vol 43, Iss 4, Pp 415-434 (2023)
Abstract Background Antiangiogenic tyrosine kinase inhibitors (TKIs) provide one of the few therapeutic options for effective treatment of hepatocellular carcinoma (HCC). However, patients with HCC often develop resistance toward antiangiogenic TKIs,
Externí odkaz:
https://doaj.org/article/b014bbfe6ace4455a5688b7b5212c659
Autor:
Kota Nakashima, Jun Akiba, Shinji Mizuochi, Masamichi Nakayama, Naohiro Yoshida, Kenichi Koushi, Takefumi Yoshida, Fumihiko Fujita, Hitoshi Obara, Tatsuyuki Kakuma, Yoshito Akagi, Hirohisa Yano
Publikováno v:
Human Pathology Reports, Vol 31, Iss , Pp 300690- (2023)
Aims: Although venous invasion is an important prognostic factor for colorectal cancer, it may be significantly underestimated in actual daily diagnosis. In this study, hematoxylin–eosin (HE)- and Elastica van Gieson (EVG)-stained specimens of colo
Externí odkaz:
https://doaj.org/article/5e80dfac81cd46fd8b61175f4a646c0f
Autor:
Hiroyuki Suzuki, Hideki Iwamoto, Ken Yamamoto, Mai Tsukaguchi, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Takashi Niizeki, Shusuke Okamura, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Ryoko Kuromatsu, Toru Hisaka, Hirohisa Yano, Hironori Koga, Takuji Torimura
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 4, Pp 555-562 (2022)
Background and Aims: Hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) progresses with a highly multicentric occurrence (MO) even after radical hepatectomy. Despite several efforts to clarify the pathogenesis of MO, the underlying molecu
Externí odkaz:
https://doaj.org/article/030a69a874c843fc9efe892d239bae68
Autor:
Masatoshi Kudo, Yusuke Kawamura, Kiyoshi Hasegawa, Ryosuke Tateishi, Kazuya Kariyama, Shuichiro Shiina, Hidenori Toyoda, Yasuharu Imai, Atsushi Hiraoka, Masafumi Ikeda, Namiki Izumi, Michihisa Moriguchi, Sadahisa Ogasawara, Yasunori Minami, Kazuomi Ueshima, Takamichi Murakami, Shiro Miyayama, Osamu Nakashima, Hirohisa Yano, Michiie Sakamoto, Etsuro Hatano, Mitsuo Shimada, Norihiro Kokudo, Satoshi Mochida, Tetsuo Takehara
Publikováno v:
Liver Cancer, Vol 10, Iss 3, Pp 181-223 (2021)
The Clinical Practice Manual for Hepatocellular Carcinoma was published based on evidence confirmed by the Evidence-based Clinical Practice Guidelines for Hepatocellular Carcinoma along with consensus opinion among a Japan Society of Hepatology (JSH)
Externí odkaz:
https://doaj.org/article/70183503931c478fbf775ba50c23951a
Autor:
Yoshiki Naito, Masayuki Tsuneki, Noriyoshi Fukushima, Yutaka Koga, Michiyo Higashi, Kenji Notohara, Shinichi Aishima, Nobuyuki Ohike, Takuma Tajiri, Hiroshi Yamaguchi, Yuki Fukumura, Motohiro Kojima, Kenichi Hirabayashi, Yoshihiro Hamada, Tomoko Norose, Keita Kai, Yuko Omori, Aoi Sukeda, Hirotsugu Noguchi, Kaori Uchino, Junya Itakura, Yoshinobu Okabe, Yuichi Yamada, Jun Akiba, Fahdi Kanavati, Yoshinao Oda, Toru Furukawa, Hirohisa Yano
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Histopathological diagnosis of pancreatic ductal adenocarcinoma (PDAC) on endoscopic ultrasonography-guided fine-needle biopsy (EUS-FNB) specimens has become the mainstay of preoperative pathological diagnosis. However, on EUS-FNB specimens,
Externí odkaz:
https://doaj.org/article/8efa37602ae04180b4b65201336e8c57
Autor:
Yoriko Nomura, Hisamune Sakai, Jun Akiba, Toru Hisaka, Toshihiro Sato, Yuichi Goto, Masanori Akashi, Shogo Fukutomi, Daisuke Muroya, Hiroki Kanno, Shusuke Okamura, Yuta Yano, Hirohisa Yano, Yoshito Akagi, Koji Okuda
Publikováno v:
BMC Surgery, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is primary cancer of the liver with poor prognosis because of its high potential for recurrence and metastasis. We experienced a rare case of ICC with hematogenous metastasis to the falciform
Externí odkaz:
https://doaj.org/article/5c0f414d59314538ac469a28be7b00b2
Autor:
Hiroyuki Suzuki, Teruko Arinaga-Hino, Tomoya Sano, Yutaro Mihara, Hironori Kusano, Tatsuki Mizuochi, Takao Togawa, Shogo Ito, Tatsuya Ide, Reiichiro Kuwahara, Keisuke Amano, Toshihiro Kawaguchi, Hirohisa Yano, Masayoshi Kage, Hironori Koga, Takuji Torimura
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Benign recurrent intrahepatic cholestasis type 1 (BRIC1) is a rare autosomal recessive disorder that is characterized by intermittent episodes of jaundice and intense pruritus and caused by pathogenic variants of adenosine triphosphatase phospholipid
Externí odkaz:
https://doaj.org/article/273337d8cf2a4d5f9cc9e33997d0884e
Autor:
Akihiko Kawahara, Jun Akiba, Hirohisa Yano, Ambrogio Fassina, Rocco Cappellesso, Yoshiki Naito, Maria Guido, Paolo Simioni, Giuliana Cortese, Lorenzo Nicolè, Tiziana Sanavia, Valeria Maffeis, Claudia Maria Radu, Davide Serafin, Giacomo Zanus
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Hepatocellular carcinoma (HCC) is a highly lethal cancer and the second leading cause of cancer-related deaths worldwide. As demonstrated in other solid neoplasms and HCC, infiltrating CD8+ T cells seem to be related to a better prognosis,
Externí odkaz:
https://doaj.org/article/0a285e23f19c4f498713d63cb388c4d4