Zobrazeno 1 - 10
of 187
pro vyhledávání: '"HIROAKI OZASA"'
Autor:
Ryo Miyata, MD, PhD, Masatsugu Hamaji, MD, PhD, Akiyoshi Nakakura, MSc, Hiroaki Ozasa, MD, PhD, Masashi Kobayashi, MD, PhD, Makoto Sonobe, MD, PhD, Ryo Miyahara, MD, PhD, Akihiro Aoyama, MD, PhD, Ryutaro Kikuchi, MD, PhD, Hiroshi Date, MD, PhD
Publikováno v:
Annals of Thoracic Surgery Short Reports, Vol 2, Iss 3, Pp 469-473 (2024)
Background: There is a dearth of data on outcomes of postoperative chemotherapy after neoadjuvant therapy followed by surgery in patients with locally advanced non-small cell lung cancer (NSCLC). The objective of this study was to compare survival ou
Externí odkaz:
https://doaj.org/article/9e6289b6dc304de799f4eeb0f1c1ff31
Autor:
Mari Yokoi, Atsushi Yonezawa, Daiki Hira, Tomohiro Handa, Kiminobu Tanizawa, Shunsaku Nakagawa, Masahiro Tsuda, Yasuaki Ikemi, Ryo Itotani, Hironori Yoshida, Motoo Nomura, Junichi Matsubara, Kosaku Murakami, Hiroaki Ozasa, Manabu Muto, Tomohiro Terada
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Background Interstitial lung disease (ILD) is one of the most common fatal immune-related adverse events (irAEs). ILD development adversely affects the continuation of anticancer drug therapy, including immune checkpoint inhibitor (ICI) ther
Externí odkaz:
https://doaj.org/article/f2314e6a38524863a43f8bf9cf08fa33
Autor:
Kazutaka Hosoya, Hiroaki Ozasa, Masahiro Tanji, Hiroshi Yoshida, Hitomi Ajimizu, Takahiro Tsuji, Hironori Yoshida, Yukinori Terada, Noritaka Sano, Yohei Mineharu, Susumu Miyamoto, Toyohiro Hirai, Yoshiki Arakawa
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Brain metastasis (BrM) is prevalent among patients with NSCLC, and surgical resection of BrM constitutes a promising treatment strategy for local management and histopathological diagnosis, although it is offered for a select grou
Externí odkaz:
https://doaj.org/article/f3bf40f9ddff4063840a65ebc9bc60ca
Autor:
Hiroshi Yoshida, Hiroaki Ozasa, Kentaro Hashimoto, Yusuke Shima, Keiichiro Suminaga, Hitomi Ajimizu, Takashi Nomizo, Hironori Yoshida, Masahiro Yoshioka, Masashi Kanai, Takehito Shukuya, Manabu Muto, Toyohiro Hirai
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 14, Iss , Pp 100286- (2024)
Among cases of non-small cell lung cancer (NSCLC) with EGFR mutations, NSCLC with deletions in EGFR exon 19 or 21 L858R account for 85 %. Frequency of NSCLC with minor mutations in EGFR is about 9 %, whilst EGFR exon 20 insertion mutation account for
Externí odkaz:
https://doaj.org/article/9c163bc24b6e4a9181dc97cc3c256896
Autor:
Yuki Katayama, Tadaaki Yamada, Keiko Tanimura, Shinsaku Tokuda, Kenji Morimoto, Soichi Hirai, Yohei Matsui, Ryota Nakamura, Masaki Ishida, Hayato Kawachi, Kazue Yoneda, Kazutaka Hosoya, Takahiro Tsuji, Hiroaki Ozasa, Akihiro Yoshimura, Masahiro Iwasaku, Young Hak Kim, Mano Horinaka, Toshiyuki Sakai, Takahiro Utsumi, Shinsuke Shiotsu, Takayuki Takeda, Ryohei Katayama, Koichi Takayama
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-13 (2023)
Abstract Anaplastic lymphoma kinase (ALK)-tyrosine kinase inhibitors rarely elicit complete responses in patients with advanced ALK-rearranged non-small cell lung cancer (NSCLC), as a small population of tumor cells survives due to adaptive resistanc
Externí odkaz:
https://doaj.org/article/583207af794a452d86780039dd00b9de
Autor:
Hitomi Ajimizu, Hiroaki Ozasa, Susumu Sato, Tomoko Funazo, Yuichi Sakamori, Takashi Nomizo, Kiyomitsu Kuninaga, Tatsuya Ogimoto, Kazutaka Hosoya, Masatoshi Yamazoe, Takahiro Tsuji, Hironori Yoshida, Ryo Itotani, Kentaro Ueno, Young Hak Kim, Shigeo Muro, Toyohiro Hirai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) may coexist with lung cancer, but the impact on prognosis is uncertain. Moreover, it is unclear whether pharmacological treatment for COPD improves the patient’s prognosis. We retrospectively in
Externí odkaz:
https://doaj.org/article/f3c791af74a046499c35180097eeba07
Autor:
Hitomi Ajimizu, Hiroaki Ozasa, Susumu Sato, Tomoko Funazo, Yuichi Sakamori, Takashi Nomizo, Kiyomitsu Kuninaga, Tatsuya Ogimoto, Kazutaka Hosoya, Masatoshi Yamazoe, Takahiro Tsuji, Hironori Yoshida, Ryo Itotani, Kentaro Ueno, Young Hak Kim, Shigeo Muro, Toyohiro Hirai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/54a067459b054ee180ce6a077620ee5a
Autor:
Takahiro Tsuji, Hiroaki Ozasa, Wataru Aoki, Shunsuke Aburaya, Tomoko Yamamoto Funazo, Koh Furugaki, Yasushi Yoshimura, Masatoshi Yamazoe, Hitomi Ajimizu, Yuto Yasuda, Takashi Nomizo, Hironori Yoshida, Yuichi Sakamori, Hiroaki Wake, Mitsuyoshi Ueda, Young Hak Kim, Toyohiro Hirai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Relapse is a limitation for the efficacy of the anaplastic lymphoma kinase (ALK)-inhibitor alectinib in ALK-rearranged lung cancer. Here, the authors show that YAP1 activation upon alectinib treatment leads to therapy resistance and that inhibiting b
Externí odkaz:
https://doaj.org/article/3f80ddddea7640be87705e31f5e46a2a
Autor:
Takahiro Tsuji, Young Hak Kim, Hiroaki Ozasa, Yuichi Sakamori, Hiroki Nagai, Hitomi Ajimizu, Yoshitaka Yagi, Atsuyuki Furukawa, Hironori Haga, Michiaki Mishima
Publikováno v:
Respiratory Medicine Case Reports, Vol 15, Iss C, Pp 48-50 (2015)
Introduction: Pulmonary spindle cell carcinoma (SpCC) is a rare subtype of non-small-cell lung cancer (NSCLC) and, in general, is chemoresistance. Case: A sixty-five year-old male patient with metastatic pulmonary SpCC was initially treated with cisp
Externí odkaz:
https://doaj.org/article/072e36e2b7f54ce7a275f59bb9829aa0
Disease Flare after Discontinuation of Crizotinib in Anaplastic Lymphoma Kinase-Positive Lung Cancer
Publikováno v:
Case Reports in Oncology, Vol 6, Iss 2, Pp 430-433 (2013)
We report the case of a 50-year-old male former smoker. He was diagnosed as having lung adenocarcinoma and treated with induction chemoradiation therapy followed by surgery and adjuvant chemotherapy. Molecular testing revealed that his tumor had an e
Externí odkaz:
https://doaj.org/article/c5ea3e10daac4a3ebf2a033169b87290