Zobrazeno 1 - 10
of 144
pro vyhledávání: '"HIF3a"'
Autor:
Jakub Slawski, Maciej Jaśkiewicz, Anna Barton, Sylwia Kozioł, James F. Collawn, Rafał Bartoszewski
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151386- (2024)
Hypoxia-inducible factors (HIFs) are transcription factors that reprogram the transcriptome for cells to survive hypoxic insults and oxidative stress. They are important during embryonic development and reprogram the cells to utilize glycolysis when
Externí odkaz:
https://doaj.org/article/a8db4514b4f84c12839ff955b08e8b07
Publikováno v:
International Dental Journal, Vol 73, Iss 5, Pp 636-644 (2023)
ABSTRACT: Background: The dysregulated long noncoding RNAs (lncRNAs) are implicated in progression of various diseases, including pulpitis. Double homeobox A pseudogene 8 (DUXAP8) has been found to be upregulated in pulpitis. Herein, the functional m
Externí odkaz:
https://doaj.org/article/e4336d8e845f4a43b80f9ed6728f6c62
Publikováno v:
Genetics and Molecular Biology, Vol 46, Iss 3 suppl 1 (2024)
Abstract Aquatic mammals (marine and freshwater species) share significant and similar adaptations, enabling them to tolerate hypoxia during regular breath-hold diving. Despite the established importance of HIF1A, a master regulator in the molecular
Externí odkaz:
https://doaj.org/article/4bdd3264cf9043c583c8b6c5e4f2f746
Akademický článek
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Autor:
Maciej Jaśkiewicz, Adrianna Moszyńska, Marcin Serocki, Jarosław Króliczewski, Sylwia Bartoszewska, James F. Collawn, Rafal Bartoszewski
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 21, Pp 454-469 (2022)
The adaptive response to hypoxia involves the transcriptional induction of three transcription factors called hypoxia inducible factor alpha 1, 2 and 3 (HIF-1α, HIF-2α, and HIF-3α) which dimerize with constitutively expressed beta chains that toge
Externí odkaz:
https://doaj.org/article/fe0213f64af444338ce08c32f8a9c6ed
Autor:
Toby Mansell, David Burgner, Anne-Louise Ponsonby, Fiona Collier, Angela Pezic, Peter Vuillermin, Markus Juonala, Joanne Ryan, Richard Saffery
Publikováno v:
Epigenetics, Vol 15, Iss 12, Pp 1361-1369 (2020)
Methylation levels at the hypoxia-inducible factor 3α gene (HIF3A) in blood have been linked to body mass index (BMI) in adults. Despite evidence implicating HIF3A in angiogenesis and metabolism, no studies have examined links between HIF3A methylat
Externí odkaz:
https://doaj.org/article/b4e432d55484463f9f3900be838fc5da
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
Spinal cord injury (SCI) is caused by an external force, leading to severe dysfunction of the limbs below the injured segment. The inflammatory response plays a vital role in the prognosis of SCI. Human umbilical cord mesenchymal stem cell (hUCMSC) t
Externí odkaz:
https://doaj.org/article/e31459b468374d4daf7a53adf84841fa
Akademický článek
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Autor:
Lihui Wang, Jinjin Cao, Qianqian Xu, Xiaomei Lu, Xin Yang, Qiong Song, Shuai Chen, Kechen Du, Renbin Huang, Chunlin Zou
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Diabetes mellitus (DM) is an independent risk factor for cognitive impairment. Although the etiology of diabetic cognitive impairment is complex and multifactorial, the hippocampus neuronal apoptosis is recognized as a main cause of diabetes-induced
Externí odkaz:
https://doaj.org/article/40b8ab9f921942908929ac06820740ac
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Gestational diabetes mellitus (GDM) is a disease that changes the function of microvascular of placenta. MicroRNA (miRNA) expression in placenta may contribute to the pathogenesis of GDM. Here, we evaluate the role and function of miR-29b in the deve
Externí odkaz:
https://doaj.org/article/334f34d1f7b9424480501d2a84f671c6