Zobrazeno 1 - 10
of 2 892
pro vyhledávání: '"HIF1a"'
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-12 (2024)
Abstract Ovarian cancer is an extremely malignant gynaecological tumour with a poor patient prognosis and is often associated with chemoresistance. Thus, exploring new therapeutic approaches to improving tumour chemosensitivity is important. The expr
Externí odkaz:
https://doaj.org/article/be53e7bc0bfc4e008f5f6f7633f52758
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-4 (2024)
Abstract With great interest, we have read the recent article “Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery” published by Lyu et al. in Annals of the Rheumatic Dis
Externí odkaz:
https://doaj.org/article/4f9ef201e7504681b3f9d058752051d1
Autor:
Seungyoon Nam, Yeeun Lee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract To elucidate the correlation of HIF1A with clinicopathologic characteristics in patients with gastric cancer (GC), we conducted a systematic review and meta-analysis. We searched PubMed, Embase and Web of Science for studies on GC and HIF1A,
Externí odkaz:
https://doaj.org/article/6c15b51c8dec489aaeb5efcbfe1532b1
Autor:
Chuncheng Liu, Gehui Liu, Xinyang Zuo, Donghui Qu, Yefeng Sun, Linan Liu, Xiujuan Zhao, Jun Li, Lu Cai
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Hypoxia can cause a variety of diseases, including ischemic stroke and neurodegenerative diseases. Within a certain range of partial pressure of oxygen, cells can respond to changes in oxygen. Changes in oxygen concentration beyond a thresho
Externí odkaz:
https://doaj.org/article/063b014f9ed44f58aa4b3cff02b523a1
Publikováno v:
Patologìâ, Vol 21, Iss 1, Pp 23-27 (2024)
In modern medical science great attention is paid to the clarification of the molecular mechanisms, which are the basis of adaptation to environmental factors of unusual origin and/or extraordinary strength. The aim of the study is to determine th
Externí odkaz:
https://doaj.org/article/1344080d03214266b804dfd84a333858
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37739- (2024)
Lung adenocarcinoma (LUAD) remains a challenge within the realm of non-small cell lung cancer (NSCLC), demanding innovative diagnostic and therapeutic solutions. In this study, we systematically detected the correlation between the expression of hypo
Externí odkaz:
https://doaj.org/article/3eee39a50ac849c49f63eac8b3cedebc
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37349- (2024)
Background: Lumbar disc degeneration (LDD) is a prevalent condition characterized by the decreased viability and functional impairment of nucleus pulposus mesenchymal stem cells (NPMSCs). Shaoyao-Gancao decoction (SGD), a traditional Chinese medicine
Externí odkaz:
https://doaj.org/article/18892074c9284a3d9e805828156e963b
Autor:
Yarong Ding, Chenlei Xie, Shuihua Feng, Zhonghang Yuan, Wei Wang, Mulin Liu, Zhongzhi Zhou, Li Chen
Publikováno v:
Digital Chinese Medicine, Vol 7, Iss 1, Pp 79-89 (2024)
Objective: To explore the mechanism of Wenyang Shengji Ointment (温阳生肌膏, WYSJO) in the treatment of diabetic wounds from the perspective of network pharmacology, and to verify it by animal experiments. Methods: The Traditional Chinese Medici
Externí odkaz:
https://doaj.org/article/268172fd953b43beab1801a20753194d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Globally, breast cancer is the second most common cause of cancer-related deaths among women. In breast cancer, microRNAs (miRNAs) are essential for both the initiation and development of tumors. It has been suggested that the tumor suppress
Externí odkaz:
https://doaj.org/article/8add4c6218bc49eeb7b633109b81323c
Autor:
Jakub Slawski, Maciej Jaśkiewicz, Anna Barton, Sylwia Kozioł, James F. Collawn, Rafał Bartoszewski
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151386- (2024)
Hypoxia-inducible factors (HIFs) are transcription factors that reprogram the transcriptome for cells to survive hypoxic insults and oxidative stress. They are important during embryonic development and reprogram the cells to utilize glycolysis when
Externí odkaz:
https://doaj.org/article/a8db4514b4f84c12839ff955b08e8b07