Zobrazeno 1 - 10
of 155
pro vyhledávání: '"HIF-1 signaling"'
Autor:
Haihua Liu, Zhijian Wang, Yanjun Li, Qian Chen, Sijia Jiang, Yue Gao, Jing Wang, Yali Chi, Jie Liu, Xiaoli Wu, Qiong Chen, Chaoqun Xiao, Mei Zhong, Chunlin Chen, Xinping Yang
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Recent studies have shown that several long non-coding RNAs (lncRNAs) in the placenta are associated with preeclampsia (PE). However, the extent to which lncRNAs may contribute to the pathological progression of PE is unclear. Res
Externí odkaz:
https://doaj.org/article/acefd4e979fe414cbf02b4bd87edae56
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Shenma Jingfu Granule, a traditional Chinese medicine formula, has been used clinically for the treatment of cerebral circulation insufficiency. However, the mechanism involved in alleviating cerebral ischemia has not yet been ful
Externí odkaz:
https://doaj.org/article/56fdea9ce67845c3940eaa5520f32b36
Autor:
Shunan Yu, Xiong Shu, Xinyu Wang, Yueyang Sheng, Shan Li, Ying Wang, Yanzhuo Zhang, Jiangfeng Tao, Xu Jiang, Chengai Wu
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e35603- (2024)
Osteoarthritis (OA) is a prevalent chronic degenerative disease that affects the bones and joints, particularly in middle-aged and elderly individuals. It is characterized by progressive joint pain, swelling, stiffness, and deformity. Notably, treatm
Externí odkaz:
https://doaj.org/article/4b88b37238454392a107d68b401d8b26
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The core of tumor cell metabolism is the management of energy metabolism due to the extremely high energy requirements of tumor cells. The purine nucleotide synthesis pathway in cells uses the purinosomes as an essential spatial structural complex. I
Externí odkaz:
https://doaj.org/article/2c84d500cd2b4bac96593d82c88936e1
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e23161- (2023)
Background: Colorectal cancer (CRC) is characterized by its aggressiveness and high fatality rate. Long noncoding RNAs (lncRNAs) as molecular scaffolding in CRC have received little attention. Methods: The TCGA database was used to find putative anti
Externí odkaz:
https://doaj.org/article/16786a7a4b8543f595f39a3638a9dee3
Akademický článek
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Akademický článek
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Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 5, Iss , Pp 100188- (2022)
ABSTRACT: Oligoasthenospermia (OAS) remains the leading cause of male infertility. Guilu-Erxian-Glue (GLEXG) is a traditional Chinese formula that exhibits beneficial effects in attenuating reproductive dysfunction. However, the mechanism of GLEXG ag
Externí odkaz:
https://doaj.org/article/068ba3a44dea409686e28fdc016bd7d8
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Ischemic stroke (IS) is a neurological condition associated with high mortality and disability rates. Although the molecular mechanisms underlying IS remain unclear, ferroptosis was shown to play an important role in its pathogenesis. Hence, we appli
Externí odkaz:
https://doaj.org/article/0711d42ad1ba4b76bb2eb8c8ecfa841e
Autor:
Xingxing Lai, Zhongxuan Zhong, Bing Lin, Yuxin Wu, Yonghao Ma, Cuiping Zhang, Yang Yang, Mingqing Zhang, Weijian Qin, Xiaoqin Fu, Hu Shu
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Hypoxia is a critical problem in intensive Epinephelus coioides aquaculture systems. In the present study, the physiological responses of E. coioides muscle to acute hypoxic stress (DO = 0.6 ± 0.1 mg/L) and reoxygenation (DO = 6.0 ± 0.1 mg/L) were
Externí odkaz:
https://doaj.org/article/6620e21e0de84e1c87d38e42e5560186