Výsledky vyhledávání

Akademický článek

Developmental plasticity of human foetal femur-derived cells in pellet culture: self assembly of an osteoid shell around a cartilaginous core

Autor: AT El-Serafi, DI Wilson, HI Roach, ROC Oreffo

Publikováno v: European Cells & Materials, Vol 21, Pp 558-567 (2011)

This study has examined the osteogenic and chondrogenic differentiation of human foetal femur-derived cells in 3-dimensional pellet cultures. After culture for 21-28 days in osteogenic media, the pellets acquired a unique configuration that consisted

Externí odkaz: https://doaj.org/article/badea83b70964494b6b23cd7e23dc284

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Akademický článek

Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis

Autor: MB Goldring, M Otero, DA Plumb, C Dragomir, M Favero, K El Hachem, K Hashimoto, HI Roach, E Olivotto, RM Borzì, KB Marcu

Publikováno v: European Cells & Materials, Vol 21, Pp 202-220 (2011)

Human cartilage is a complex tissue of matrix proteins that vary in amount and orientation from superficial to deep layers and from loaded to unloaded zones. A major challenge to efforts to repair cartilage by stem cell-based and other tissue enginee

Externí odkaz: https://doaj.org/article/f10e4bfb4f6e45649c439f176540e21d

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Changes in immunolocalisation of beta-dystroglycan and specific degradative enzymes in the osteoarthritic synovium

Autor: GD Harper, Sanjay Sharma, Dariusz C. Górecki, Chun Fu Lien, Peter A. Brennan, S Wimsey, HI Roach

Publikováno v: Osteoarthritis and cartilage. 14(11)

Objective: To investigate the immunolocalisation of β-dystroglycan (β-DG) and specific matrix metalloproteinases (MMPs)-3, -9, -13 and a disintegrin like and metalloproteinase thrombospondin type 1 motif 4 (ADAMTS-4) within the joint tissues of pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f65f00e2b484d4ed574abda2420825
https://pubmed.ncbi.nlm.nih.gov/16759884

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